Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Tora Ida Henriksen"'
Autor:
Cajsa Davegårdh, Johanna Säll, Anna Benrick, Christa Broholm, Petr Volkov, Alexander Perfilyev, Tora Ida Henriksen, Yanling Wu, Line Hjort, Charlotte Brøns, Ola Hansson, Maria Pedersen, Jens U. Würthner, Klaus Pfeffer, Emma Nilsson, Allan Vaag, Elisabet Stener-Victorin, Karolina Pircs, Camilla Scheele, Charlotte Ling
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Insulin resistance and lower muscle strength in relation to mass are hallmarks of type 2 diabetes. Here, the authors report alterations in muscle stem cells from individuals with type 2 diabetes that may contribute to these phenotypes through VPS39 m
Externí odkaz:
https://doaj.org/article/7112e41c1e98491c8e3cfe67e2e5bdd8
Autor:
Cajsa Davegårdh, Elin Hall Wedin, Christa Broholm, Tora Ida Henriksen, Maria Pedersen, Bente Klarlund Pedersen, Camilla Scheele, Charlotte Ling
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-17 (2019)
Abstract Background Sex differences are known to impact muscle phenotypes, metabolism, and disease risk. Skeletal muscle stem cells (satellite cells) are important for muscle repair and to maintain functional skeletal muscle. Here we studied, for the
Externí odkaz:
https://doaj.org/article/49d48526969346c1a9737934f74b257f
Autor:
Leif Väremo, Tora Ida Henriksen, Camilla Scheele, Christa Broholm, Maria Pedersen, Mathias Uhlén, Bente Klarlund Pedersen, Jens Nielsen
Publikováno v:
Genome Medicine, Vol 9, Iss 1, Pp 1-12 (2017)
Abstract Background Skeletal muscle is one of the primary tissues involved in the development of type 2 diabetes (T2D). The close association between obesity and T2D makes it difficult to isolate specific effects attributed to the disease alone. Ther
Externí odkaz:
https://doaj.org/article/a3a7569f082e465e906b6429196810e6
Autor:
Tipwadee Bunprajun, Tora Ida Henriksen, Camilla Scheele, Bente Klarlund Pedersen, Charlotte Jane Green
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66628 (2013)
Both aging and physical inactivity are associated with increased development of insulin resistance whereas physical activity has been shown to promote increased insulin sensitivity. Here we investigated the effects of physical activity level on aging
Externí odkaz:
https://doaj.org/article/a3fe593fb23d4200ade8842e377ed8dc
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2448
Brown adipose tissue (BAT) is a thermoregulatory fat with energy-consuming properties. The location and heterogeneity of this tissue makes it complicated to sample before and after interventions in humans, and an in vitro model for mechanistic and mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::63041bf185b078cdc9c2e7af9e05453a
https://pubmed.ncbi.nlm.nih.gov/35167100
https://pubmed.ncbi.nlm.nih.gov/35167100
Publikováno v:
Methods in Molecular Biology ISBN: 9781071620861
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60315b985796a7adcb7651bbfbe8a920
https://doi.org/10.1007/978-1-0716-2087-8_14
https://doi.org/10.1007/978-1-0716-2087-8_14
Autor:
Bente Klarlund Pedersen, M. Sandri, Jens Nielsen, Leif Wigge, Camilla Scheele, Tora Ida Henriksen
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Henriksen, T I, Wigge, L V, Nielsen, J, Pedersen, B K, Sandri, M & Scheele, C 2019, ' Dysregulated autophagy in muscle precursor cells from humans with type 2 diabetes ', Scientific Reports, vol. 9 . https://doi.org/10.1038/s41598-019-44535-2
Scientific Reports
Henriksen, T I, Wigge, L V, Nielsen, J, Pedersen, B K, Sandri, M & Scheele, C 2019, ' Dysregulated autophagy in muscle precursor cells from humans with type 2 diabetes ', Scientific Reports, vol. 9 . https://doi.org/10.1038/s41598-019-44535-2
Autophagy is active during cellular remodeling including muscle differentiation. Muscle differentiation is dysregulated in type 2 diabetes and we therefore hypothesize that muscle precursor cells from people with type 2 diabetes (T2DM) have a dysregu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2f06a7760c9a8c25fcaadc1f8ed8701
http://link.springer.com/article/10.1038/s41598-019-44535-2
http://link.springer.com/article/10.1038/s41598-019-44535-2
Autor:
Tora Ida Henriksen, Ninna S. Hansen, Bente Klarlund Pedersen, Heidi S. Schultz, Maria Pedersen, Camilla Scheele, Therese Juhlin Larsen, Peter K. Davidsen, Allan Vaag, Søren Nielsen
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 6, Iss 7, Pp 770-779 (2017)
Henriksen, T I, Davidsen, P K, Pedersen, M, Schultz, H S, Hansen, N S, Larsen, T J, Vaag, A, Pedersen, B K, Nielsen, S & Scheele, C 2017, ' Dysregulation of a novel miR-23b/27b-p53 axis impairs muscle stem cell differentiation of humans with type 2 diabetes ', Molecular Metabolism, vol. 6, no. 7, pp. 770-779 . https://doi.org/10.1016/j.molmet.2017.04.006
Molecular Metabolism, Vol 6, Iss 7, Pp 770-779 (2017)
Henriksen, T I, Davidsen, P K, Pedersen, M, Schultz, H S, Hansen, N S, Larsen, T J, Vaag, A, Pedersen, B K, Nielsen, S & Scheele, C 2017, ' Dysregulation of a novel miR-23b/27b-p53 axis impairs muscle stem cell differentiation of humans with type 2 diabetes ', Molecular Metabolism, vol. 6, no. 7, pp. 770-779 . https://doi.org/10.1016/j.molmet.2017.04.006
Objective MicroRNAs (miRNAs) are increasingly recognized as fine-tuning regulators of metabolism, and are dysregulated in several disease conditions. With their capacity to rapidly change gene expression, miRNAs are also important regulators of devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d729ca494936aa68fc820bd3fd2b66f
https://doi.org/10.1016/j.molmet.2017.04.006
https://doi.org/10.1016/j.molmet.2017.04.006
Autor:
Emma Nilsson, Tora Ida Henriksen, Allan Vaag, Charlotte Brøns, Ola Hansson, Cajsa Davegårdh, Klaus Pfeffer, Petr Volkov, Jens U. Wurthner, Alexander Perfilyev, Yanling Wu, Christa Broholm, Karolina Pircs, Anna Benrick, Elisabet Stener-Victorin, Johanna Säll, Camilla Scheele, Charlotte Ling, Maria Pedersen, Line Hjort
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Davegårdh, C, Säll, J, Benrick, A, Broholm, C, Volkov, P, Perfilyev, A, Henriksen, T I, Wu, Y, Hjort, L, Brøns, C, Hansson, O, Pedersen, M, Würthner, J U, Pfeffer, K, Nilsson, E, Vaag, A, Stener-Victorin, E, Pircs, K, Scheele, C & Ling, C 2021, ' VPS39-deficiency observed in type 2 diabetes impairs muscle stem cell differentiation via altered autophagy and epigenetics ', Nature Communications, vol. 12, no. 1, 2431 . https://doi.org/10.1038/s41467-021-22068-5
Nature Communications
Davegårdh, C, Säll, J, Benrick, A, Broholm, C, Volkov, P, Perfilyev, A, Henriksen, T I, Wu, Y, Hjort, L, Brøns, C, Hansson, O, Pedersen, M, Würthner, J U, Pfeffer, K, Nilsson, E, Vaag, A, Stener-Victorin, E, Pircs, K, Scheele, C & Ling, C 2021, ' VPS39-deficiency observed in type 2 diabetes impairs muscle stem cell differentiation via altered autophagy and epigenetics ', Nature Communications, vol. 12, no. 1, 2431 . https://doi.org/10.1038/s41467-021-22068-5
Nature Communications
Insulin resistance and lower muscle quality (strength divided by mass) are hallmarks of type 2 diabetes (T2D). Here, we explore whether alterations in muscle stem cells (myoblasts) from individuals with T2D contribute to these phenotypes. We identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2312f9b2a8a0660bcad24ec724df50
https://pubmed.ncbi.nlm.nih.gov/33976394
https://pubmed.ncbi.nlm.nih.gov/33976394
Autor:
Tora Ida Henriksen, Charlotte Ling, Elin Hall Wedin, Bente Klarlund Pedersen, Christa Broholm, Camilla Scheele, Cajsa Davegårdh, Maria Pedersen
Publikováno v:
Stem Cell Research & Therapy
Davegardh, C, Wedin, E H, Broholm, C, Henriksen, T I, Pedersen, M, Pedersen, B K, Scheele, C & Ling, C 2019, ' Sex influences DNA methylation and gene expression in human skeletal muscle myoblasts and myotubes ', Stem Cell Research & Therapy, vol. 10 . https://doi.org/10.1186/s13287-018-1118-4
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-17 (2019)
Davegardh, C, Wedin, E H, Broholm, C, Henriksen, T I, Pedersen, M, Pedersen, B K, Scheele, C & Ling, C 2019, ' Sex influences DNA methylation and gene expression in human skeletal muscle myoblasts and myotubes ', Stem Cell Research & Therapy, vol. 10 . https://doi.org/10.1186/s13287-018-1118-4
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-17 (2019)
Background Sex differences are known to impact muscle phenotypes, metabolism, and disease risk. Skeletal muscle stem cells (satellite cells) are important for muscle repair and to maintain functional skeletal muscle. Here we studied, for the first ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b899c217b832aab58c694cab799ae27
http://europepmc.org/articles/PMC6332625
http://europepmc.org/articles/PMC6332625