Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Tor-Christian Aase Johannessen"'
Autor:
Shigeo Ohba, Tor-Christian Aase Johannessen, Kamalakar Chatla, Xiaodong Yang, Russell O. Pieper, Joydeep Mukherjee
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114314- (2024)
Externí odkaz:
https://doaj.org/article/5f2d54b730974ff891ca95e5951a116d
Autor:
Inge C Olsen, Thomas Henry, Corina Silvia Rueegg, Asgeir S Jakola, Hanne Blakstad, Petter Brandal, Liv Cathrine Heggebø, Ida Maria Henriksen Borgen, Hillevi Rylander, Cecilie Kiserud, Tonje Haug Nordenmark, Taran Paulsen Hellebust, Morten Egeberg Evensen, Magnus Gustavsson, Christina Ramberg, Mette Sprauten, Henriette Magelssen, Janani Moorthy, Karin Andersson, Ingela Raunert, Cecilie Moe, Carin Granlund, Dorota Goplen, Jorunn Brekke, Tor-Christian Aase Johannessen, Tora Skeidsvoll Solheim, Kirsten Marienhagen, Øyvind Humberset, Per Bergström, Måns Agrup, Ludvig Dahl, Michael Gubanski, Helene Gojon, Carl-Johan Brahme, Isabelle Rydén, Einar O Vik-Mo, Hanne C. Lie, Lars Asphaug, Maziar Hervani, Ingrid Kristensen, Rolf J Ledal, Eskil Degsell, Katja Werlenius, Malin Blomstrand
Publikováno v:
BMJ Open, Vol 13, Iss 3 (2023)
Introduction The use of proton therapy increases globally despite a lack of randomised controlled trials demonstrating its efficacy and safety. Proton therapy enables sparing of non-neoplastic tissue from radiation. This is principally beneficial and
Externí odkaz:
https://doaj.org/article/a71f1463c05244a9a4ac7eb02407367a
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
PKM2 is a phosphotyrosine-binding glycolytic enzyme upregulated in many cancers, including glioma, and contributes to tumor growth by regulating cell cycle progression. We noted, however, that in multiple glioma cell lines, PKM2 knock-down resulted i
Externí odkaz:
https://doaj.org/article/a1305208df1a41ea9ae4ec8ca6e8777c
Publikováno v:
Molecular & Cellular Oncology, Vol 8, Iss 2 (2021)
The glycolytic enzyme PGAM1 is overexpressed in gliomas where it efficiently facilitates the repair of DNA damage. Mechanistically, PGAM1 prevents inactivation of the ataxia-telangiectasia mutated (ATM) signaling pathway by sequestering the wild-type
Externí odkaz:
https://doaj.org/article/2157ac1cb76a48b296b954019542cc9b
Autor:
Terje Sundstrøm, Leif Oltedal, Anette Storstein, Hrvoje Miletic, Tor-Christian Aase Johannessen, Frits Thorsen, Stephanie Schipmann-Miletic, Erlend Moen Taule
Publikováno v:
Tidsskrift for Den norske legeforening.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3ba225d9d3f9dcb01dcdda5ea865fad
https://doi.org/10.4045/tidsskr.21.0809
https://doi.org/10.4045/tidsskr.21.0809
Autor:
Liv Cathrine Heggebø, Ida Maria Henriksen Borgen, Hillevi Rylander, Cecilie Kiserud, Tonje Haug Nordenmark, Taran Paulsen Hellebust, Morten Egeberg Evensen, Magnus Gustavsson, Christina Ramberg, Mette Sprauten, Henriette Magelssen, Hanne Blakstad, Janani Moorthy, Karin Andersson, Ingela Raunert, Thomas Henry, Cecilie Moe, Carin Granlund, Dorota Goplen, Jorunn Brekke, Tor-Christian Aase Johannessen, Tora Skeidsvoll Solheim, Kirsten Marienhagen, Øyvind Humberset, Per Bergström, Måns Agrup, Ludvig Dahl, Michael Gubanski, Helene Gojon, Carl-Johan Brahme, Isabelle Rydén, Asgeir S Jakola, Einar O Vik-Mo, Hanne C. Lie, Lars Asphaug, Maziar Hervani, Ingrid Kristensen, Corina Silvia Rueegg, Inge C Olsen, Rolf J Ledal, Eskil Degsell, Katja Werlenius, Malin Blomstrand, Petter Brandal
Publikováno v:
BMJ Open. 13:e070071
IntroductionThe use of proton therapy increases globally despite a lack of randomised controlled trials demonstrating its efficacy and safety. Proton therapy enables sparing of non-neoplastic tissue from radiation. This is principally beneficial and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb6ad25830030f8f23a285481e10dc8a
https://doi.org/10.1136/bmjopen-2022-070071
https://doi.org/10.1136/bmjopen-2022-070071
Autor:
Russell O. Pieper, Ajay Pandita, Joydeep Mukherjee, Chatla Kamalakar, Rolf Bjerkvig, Yongjian Tang, Tor-Christian Aase Johannessen, Cecilia Dalle-Ore, Shigeo Ohba
Publikováno v:
Science Translational Medicine. 13
About 10% of all tumors, including most lower-grade astrocytoma, rely on the alternative lengthening of telomere (ALT) mechanism to resolve telomeric shortening and avoid limitations on their growth. Here, we found that dependence on the ALT mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaccb8969a98aee6540b27761c0007f4
https://doi.org/10.1126/scitranslmed.abc7211
https://doi.org/10.1126/scitranslmed.abc7211
Autor:
Joydeep Mukherjee, Russell O. Pieper, Tor-Christian Aase Johannessen, Shigeo Ohba, Xiaodong Yang, Kamalakar Chatla
Publikováno v:
Cell Reports
The metabolic enzyme phosphoglycerate mutase 1 (PGAM1) is overexpressed in several types of cancer, suggesting an additional function beyond its established role in the glycolytic pathway. We here report that PGAM1 is overexpressed in gliomas where i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a72baabb019d4dc427fcff91d8d3ef4
https://hdl.handle.net/11250/2760979
https://hdl.handle.net/11250/2760979
Publikováno v:
Neuro Oncol
BACKGROUND: Glioblastoma (GBM) is the most common primary malignant adult brain tumor. Temozolomide (TMZ) is the standard of care and is most effective in GBMs that lack the DNA repair protein O(6)-methylguanine-DNA methyltransferase (MGMT). Moreover
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a294936bf8bf94177cd8471268ed916e
https://doi.org/10.1093/neuonc/noz196
https://doi.org/10.1093/neuonc/noz196
Publikováno v:
Mol Cell Oncol
The glycolytic enzyme PGAM1 is overexpressed in gliomas where it efficiently facilitates the repair of DNA damage. Mechanistically, PGAM1 prevents inactivation of the ataxia-telangiectasia mutated (ATM) signaling pathway by sequestering the wild-type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dacf7d4859e672d8e297000a529f329
https://doi.org/10.1080/23723556.2021.1875804
https://doi.org/10.1080/23723556.2021.1875804