Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Tor C Savidge"'
Autor:
Jonathan Ström, Johan Tham, Fredrik Månsson, Jonas Ahl, Tor C Savidge, Sara M Dann, Fredrik Resman
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169386 (2017)
Recently, metabolomics studies have suggested that the neurotransmitter γ-amino butyric acid (GABA) may modulate C. difficile infection (CDI) pathogenesis. In the present study, we investigated the association between GABA-modulating pharmaceuticals
Externí odkaz:
https://doaj.org/article/089079c2cc1b4ca69f9cad86a3bf62b5
Autor:
Hua Yu, Kevin Chen, Jianguo Wu, Zhiyong Yang, Lianfa Shi, Lydia L Barlow, David M Aronoff, Kevin W Garey, Tor C Savidge, Erik C von Rosenvinge, Ciaran P Kelly, Hanping Feng
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124235 (2015)
Toxemia can develop in Clostridium difficile-infected animals, and correlates with severe and fulminant disease outcomes. Circumstantial evidence suggests that toxemia may occur in patients with C. difficile infection (CDI), but positive diagnosis is
Externí odkaz:
https://doaj.org/article/5d7fdee08f9a40f0a8fc5ec46501e838
Autor:
Qinglong Wu, Prapaporn Boonma, Shyam Badu, Nazli Yalcinkaya, Sik Yu So, Kevin W. Garey, Kent Williams, L. Eugene Arnold, Robert J. Shulman, Richard Kellermayer, Tor C. Savidge
Publikováno v:
npj Biofilms and Microbiomes, Vol 9, Iss 1, Pp 1-13 (2023)
Abstract Fecal microbiota transplantation (FMT) has proven to be an effective treatment for recurrent Clostridioides difficile infection (rCDI) in both adult and pediatric patients. However, as microbiome development is a critical factor in children,
Externí odkaz:
https://doaj.org/article/8b7a58a0d8e749a7b279205e86da31e7
Autor:
Laura D. Hughes, Ginger Tsueng, Jack DiGiovanna, Thomas D. Horvath, Luke V. Rasmussen, Tor C. Savidge, Thomas Stoeger, Serdar Turkarslan, Qinglong Wu, Chunlei Wu, Andrew I. Su, Lars Pache, the NIAID Systems Biology Data Dissemination Working Group
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-7 (2023)
Externí odkaz:
https://doaj.org/article/c65ba8cb83f0451b9d283f3f55ebeb19
Autor:
Ginger Tsueng, Marco A. Alvarado Cano, José Bento, Candice Czech, Mengjia Kang, Lars Pache, Luke V. Rasmussen, Tor C. Savidge, Justin Starren, Qinglong Wu, Jiwen Xin, Michael R. Yeaman, Xinghua Zhou, Andrew I. Su, Chunlei Wu, Liliana Brown, Reed S. Shabman, Laura D. Hughes, the NIAID Systems Biology Data Dissemination Working Group
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-13 (2023)
Abstract Biomedical datasets are increasing in size, stored in many repositories, and face challenges in FAIRness (findability, accessibility, interoperability, reusability). As a Consortium of infectious disease researchers from 15 Centers, we aim t
Externí odkaz:
https://doaj.org/article/9a98c238656940ee8cc5844ae1782732
Autor:
Ying Xiao, Haifeng Lian, Xiaoying S. Zhong, Srikruthi S. Krishnachaitanya, Yingzi Cong, Roderick H. Dashwood, Tor C. Savidge, Don W. Powell, Xiaowei Liu, Qingjie Li
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundPrevious studies implicated matrix metalloproteinases (MMPs), such as MMP-7, in inflammatory bowel diseases (IBD) by showing increased activity during inflammation of the gut. However, the pathophysiological roles of MMP-7 have not been cle
Externí odkaz:
https://doaj.org/article/670bbb529b8447fea1bf5c6bdeff3bf2
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 321:G639-G655
Emerging evidence links dietary fiber with altered gut microbiota composition and bile acid signaling in maintaining metabolic health. Yeast β-glucan (Y-BG) is a dietary supplement known for its immunomodulatory effect, yet its impact on the gut mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58fcab170b020a8a50285524ff873f02
https://doi.org/10.1152/ajpgi.00226.2021
https://doi.org/10.1152/ajpgi.00226.2021
Publikováno v:
J Pediatric Infect Dis Soc
Clostridioides difficile has become the most common healthcare-associated pathogen in the United States, leading the US Centers for Disease Control and Prevention (CDC) to classify C. difficile as an “urgent” public health threat that requires
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963bf6376f5cab0b39ca3156247e1225
https://doi.org/10.1093/jpids/piab089
https://doi.org/10.1093/jpids/piab089
Autor:
Abria R. Magee, Tor C. Savidge, Richard Kellermayer, Claire E. Bocchini, Faith D. Ihekweazu, James Versalovic, Qinglong Wu, Numan Oezguen, Dorottya Nagy-Szakal, Emily B. Hollister, Jennifer K. Spinler, Karen Queliza, Robert J. Shulman, Ruth Ann Luna
Publikováno v:
J Pediatr Gastroenterol Nutr
OBJECTIVES: Fecal microbiota transplantation (FMT) is arguably the most effective treatment for recurrent Clostridioides difficile infection (rCDI). Clinical reports on pediatric FMT have not systematically evaluated microbiome restoration in patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f86902c0d7a858ad5a38415e9644fa45
https://doi.org/10.1097/mpg.0000000000003336
https://doi.org/10.1097/mpg.0000000000003336
Autor:
Cristian Coarfa, Matthew J. Robertson, James R. Broughman, Mark Donowitz, Mary K. Estes, Carolyn Bomidi, Sue E. Crawford, Sarah E. Blutt, Xi-Lei Zeng, Mary Elizabeth M. Tessier, F. Blaine Hollinger, Steven A. Curley, Tor C. Savidge
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
The use of human tissue stem cell-derived organoids has advanced our knowledge of human physiological and pathophysiological processes that are unable to be studied using other model systems. Increased understanding of human epithelial tissues includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b0b6b9b948ccedd94ba5eece7ce879d
https://doi.org/10.1152/ajpgi.00177.2021
https://doi.org/10.1152/ajpgi.00177.2021