Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Toqa El Nahhas"'
Publikováno v:
Saudi Pharmaceutical Journal, Vol 28, Iss 4, Pp 381-386 (2020)
Foretinib, an oral multikinase inhibitor, is known to have anti-tumor effects against cancers. The doses and the levels of foretinib vary based on the type of cancer to be treated. An accurate and precise method is required to determine the level of
Externí odkaz:
https://doaj.org/article/f815802691824a6f9849d5a1573d5da2
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 1, Pp 70-78 (2022)
Abstract Tacrolimus is the key component of most contemporary immunosuppressive drug regimens for the prevention of transplant rejection. Area under the concentration time curve over 24 h (AUC0–24) predicts efficacy, but predose (trough) tacrolimus
Externí odkaz:
https://doaj.org/article/7293ea966731495badd8b36e815d2f8d
Publikováno v:
Molecules, Vol 25, Iss 7, p 1600 (2020)
Baricitinib, is a selective and reversible Janus kinase inhibitor, is commonly used to treat adult patients with moderately to severely active rheumatoid arthritis (RA). A fast, reproducible and sensitive method of liquid chromatography-tandem mass s
Externí odkaz:
https://doaj.org/article/4f31f7fbc22848a7954d92839b2cbd31
Publikováno v:
Clinical and Translational Science
Clinical and Translational Science, Vol 15, Iss 1, Pp 70-78 (2022)
Clinical and Translational Science, Vol 15, Iss 1, Pp 70-78 (2022)
Tacrolimus is the key component of most contemporary immunosuppressive drug regimens for the prevention of transplant rejection. Area under the concentration time curve over 24 h (AUC0–24) predicts efficacy, but predose (trough) tacrolimus blood co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172268806e32ff4614f5ba0b8562036d
https://pubmed.ncbi.nlm.nih.gov/34780122
https://pubmed.ncbi.nlm.nih.gov/34780122
Publikováno v:
Molecules
Volume 25
Issue 7
Molecules, Vol 25, Iss 1600, p 1600 (2020)
Volume 25
Issue 7
Molecules, Vol 25, Iss 1600, p 1600 (2020)
Baricitinib, is a selective and reversible Janus kinase inhibitor, is commonly used to treat adult patients with moderately to severely active rheumatoid arthritis (RA). A fast, reproducible and sensitive method of liquid chromatography-tandem mass s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f8ee353bd4d3887d8523e68b1364fb
Autor:
Gamal Ae Mostafa, Khalid A. Al-Rashood, Muzaffar Iqbal, Yousef Asiri, Toqa El-Nahhas, Essam Ezzeldin
Publikováno v:
Bioanalysis. 10:1077-1086
Aim: Mozavaptan is a nonpeptide vasopressin receptor antagonist approved for the treatment of ectopic antidiuretic hormone secretion syndrome. Methods & results: A simple, rapid and fully validated UPLC/MS–MS method was developed for the quantitati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b23124ebc5fb1fc25f41d6911adb56bc
https://doi.org/10.4155/bio-2018-0092
https://doi.org/10.4155/bio-2018-0092
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 1143
Pimavanserin is a new drug approved by the FDA for Parkinson's disease psychosis and other neurological disorders such as Alzheimer's disease. In this study, we developed a UPLC-MS/MS method to quantify pimavanserin disposition in the brain and its p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ebcaf4a6cfe535ccf5915ebe3921e1a
https://pubmed.ncbi.nlm.nih.gov/32174544
https://pubmed.ncbi.nlm.nih.gov/32174544
Autor:
Atholl Johnston, Verity Bainbridge, Lewis Couchman, Valentyna Povstyan, Karin Kipper, David W. Holt, Toqa El-Nahhas, Mohammed Rahman
Publikováno v:
Therapeutic drug monitoring. 41(3)
Measurement of flecainide is useful to optimize dosage and minimize risks of toxicity. Furthermore, there is a need for urgent sample analysis when flecainide is used in transplacental therapy for fetal tachycardia. To this end, we have developed and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b93ce79eb82a286e954f8fffd744043
https://pubmed.ncbi.nlm.nih.gov/30520831
https://pubmed.ncbi.nlm.nih.gov/30520831
Publikováno v:
Journal of Chromatography B. 1136:121851
A rapid, sensitive and reproducible ultra-high performance liquid chromatography mass spectrometry method was developed and validated for simultaneous determination of seven tyrosine kinase inhibitors (dasatinib, foretinib, osimertinib, gefitinib, ib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5110cd5948ffc671791191aaddb468b
https://doi.org/10.1016/j.jchromb.2019.121851
https://doi.org/10.1016/j.jchromb.2019.121851
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 166
Motesanib is a potent angiokinase inhibitor, has shown potential therapeutic effects against various cancers. An accurate, reproducible, rapid, specific, sensitive, and valid ultraperformance liquid chromatography-tandem mass spectrometry method was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f788de57c8dcf1c7e4e4995c13968d8f
https://pubmed.ncbi.nlm.nih.gov/30665192
https://pubmed.ncbi.nlm.nih.gov/30665192