Discovery of a Novel Class of Imidazo[1,2-a]Pyridines with Potent PDGFR Activity and Oral Bioavailability.

Autor: Hicken EJ; Department of Drug Discovery, Array BioPharma , 3200 Walnut Street, Boulder, Colorado 80301, United States., Marmsater FP; Department of Drug Discovery, Array BioPharma , 3200 Walnut Street, Boulder, Colorado 80301, United States., Munson MC; Department of Drug Discovery, Array BioPharma , 3200 Walnut Street, Boulder, Colorado 80301, United States., Schlachter ST; Department of Drug Discovery, Array BioPharma , 3200 Walnut Street, Boulder, Colorado 80301, United States., Robinson JE; Department of Drug Discovery, Array BioPharma , 3200 Walnut Street, Boulder, Colorado 80301, United States., Allen S; Department of Drug Discovery, Array BioPharma , 3200 Walnut Street, Boulder, Colorado 80301, United States., Burgess LE; Department of Drug Discovery, Array BioPharma , 3200 Walnut Street, Boulder, Colorado 80301, United States., DeLisle RK; Department of Drug Discovery, Array BioPharma , 3200 Walnut Street, Boulder, Colorado 80301, United States., Rizzi JP; Department of Drug Discovery, Array BioPharma , 3200 Walnut Street, Boulder, Colorado 80301, United States., Topalov GT; Department of Drug Discovery, Array BioPharma , 3200 Walnut Street, Boulder, Colorado 80301, United States., Zhao Q; Department of Drug Discovery, Array BioPharma , 3200 Walnut Street, Boulder, Colorado 80301, United States., Hicks JM; Department of Drug Discovery, Array BioPharma , 3200 Walnut Street, Boulder, Colorado 80301, United States., Kallan NC; Department of Drug Discovery, Array BioPharma , 3200 Walnut Street, Boulder, Colorado 80301, United States., Tarlton E; Department of Drug Discovery, Array BioPharma , 3200 Walnut Street, Boulder, Colorado 80301, United States., Allen A; Department of Drug Discovery, Array BioPharma , 3200 Walnut Street, Boulder, Colorado 80301, United States., Callejo M; Department of Drug Discovery, Array BioPharma , 3200 Walnut Street, Boulder, Colorado 80301, United States., Cox A; Department of Drug Discovery, Array BioPharma , 3200 Walnut Street, Boulder, Colorado 80301, United States., Rana S; Department of Drug Discovery, Array BioPharma , 3200 Walnut Street, Boulder, Colorado 80301, United States., Klopfenstein N; Department of Drug Discovery, Array BioPharma , 3200 Walnut Street, Boulder, Colorado 80301, United States., Woessner R; Department of Drug Discovery, Array BioPharma , 3200 Walnut Street, Boulder, Colorado 80301, United States., Lyssikatos JP; Department of Drug Discovery, Array BioPharma , 3200 Walnut Street, Boulder, Colorado 80301, United States.

Publikováno v: ACS medicinal chemistry letters [ACS Med Chem Lett] 2013 Nov 12; Vol. 5 (1), pp. 78-83. Date of Electronic Publication: 2013 Nov 12 (Print Publication: 2014).