Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Tooze R"'
Publikováno v:
In International Journal of Hydrogen Energy 16 October 2020 45(51):27210-27220
Upon encounter with Ag, B cells undergo a sequential process of differentiation to become Ab-secreting plasma cells. Although the key drivers of differentiation have been identified, research has been limited by the lack of in vitro models recapitula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::80c00b50cbe2815fd13572a2f0c6db6e
https://eprints.whiterose.ac.uk/181140/18/514.full.pdf
https://eprints.whiterose.ac.uk/181140/18/514.full.pdf
Akademický článek
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Autor:
Barbosa, RR, Xu, AQ, D’Andrea, D, Copley, F, Patel, H, Chakravarty, P, Clear, A, Calaminici, M, Janz, M, Zhang, B, Schmidt-Supprian, M, Wang, J, Gribben, JG, Tooze, R, Fitzgibbon, J, Franzoso, G, Rajewsky, K, Calado, DP
NF-κB and MYC are found co-deregulated in human B and plasma-cell cancers. In physiology, NF-κB is necessary for terminal B-to-plasma cell differentiation, whereas MYC repression is required. It is thus unclear if NF-κB/MYC co-deregulation is deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::6e34f141fe72f56ed17233373d92e4b2
http://hdl.handle.net/10044/1/99736
http://hdl.handle.net/10044/1/99736
Autor:
El‐Sherbiny, YM, Yusof, MYM, Psarras, A, Hensor, EMA, Kabba, KZ, Dutton, K, Mohamed, AAA, Elewaut, D, McGonagle, D, Tooze, R, Doody, G, Wittmann, M, Emery, P, Vital, EM
Publikováno v:
ARTHRITIS & RHEUMATOLOGY
Objective:Type I interferon (IFN-I) responses are broadly associated with autoimmune disease including SLE. Given the cardinal role of autoantibodies in SLE, we investigated whether a B cell-specific IFN assay might correlate with SLE activity. METHO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::812c0e5267d7eae0209c7400c61ec305
https://biblio.ugent.be/publication/8650528
https://biblio.ugent.be/publication/8650528
Autor:
Lupino, L, Perry, T, Margielewska, S, Hollows, R, Ibrahim, M, Care, M, Allegood, J, Tooze, R, Sabbadini, R, Reynolds, G, Bicknell, R, Rudzki, Z, Lin Hock, Y, Zanetto, U, Wei, W, Simmons, W, Spiegel, S, Woodman, CBJ, Rowe, M, Vrzalikova, K, Murray, PG
Publikováno v:
Leukemia
Although the over-expression of angiogenic factors is reported in diffuse large B-cell lymphoma (DLBCL), the poor response to anti-VEGF drugs observed in clinical trials suggests that angiogenesis in these tumours might be driven by VEGF-independent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f4efedfe9253bd02ee585b9f35de1296
https://eprints.whiterose.ac.uk/147267/1/s41375-019-0478-9.pdf
https://eprints.whiterose.ac.uk/147267/1/s41375-019-0478-9.pdf
Akademický článek
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Autor:
Davies, A, Cummin, TE, Barrans, S, Maishman, T, Mamot, C, Novak, U, Caddy, J, Stanton, L, Kazmi-Stokes, S, McMillan, A, Fields, P, Pocock, C, Collins, GP, Stephens, R, Cucco, F, Clipson, A, Sha, C, Tooze, R, Care, MA, Griffiths, G, Du, M-Q, Westhead, DR, Burton, C, Johnson, PWM
Publikováno v:
Davies, Andrew; Cummin, Thomas E; Barrans, Sharon; Maishman, Tom; Mamot, Christoph; Novak, Urban; Caddy, Josh; Stanton, Louise; Kazmi-Stokes, Shamim; McMillan, Andrew; Fields, Paul; Pocock, Christopher; Collins, Graham P; Stephens, Richard; Cucco, Francesco; Clipson, Alexandra; Sha, Chulin; Tooze, Reuben; Care, Matthew A; Griffiths, Gareth; ... (2019). Gene-expression profiling of bortezomib added to standard chemoimmunotherapy for diffuse large B-cell lymphoma (REMoDL-B): an open-label, randomised, phase 3 trial. The lancet oncology, 20(5), pp. 649-662. Elsevier 10.1016/S1470-2045(18)30935-5
BACKGROUND: Biologically distinct subtypes of diffuse large B-cell lymphoma can be identified using gene-expression analysis to determine their cell of origin, corresponding to germinal centre or activated B cell. We aimed to investigate whether addi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0ca200ca0986b184f9bd9d47ac4e133
Autor:
Sha, C, Barrans, S, Cucco, F, Bentley, MA, Care, MA, Cummin, T, Kennedy, H, Thompson, JS, Uddin, R, Worrillow, L, Chalkley, R, van Hoppe, M, Ahmed, S, Maishman, T, Caddy, J, Schuh, A, Mamot, C, Burton, C, Tooze, R, Davies, A, Du, MQ, Johnson, PWM, Westhead, DR
Purpose: Biologic heterogeneity is a feature of diffuse large B-cell lymphoma (DLBCL), and the existence of a subgroup with poor prognosis and phenotypic proximity to Burkitt lymphoma is well known. Conventional cytogenetics identifies some patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::9f124f785fb6f5f4abacacd2791c7a90
https://eprints.whiterose.ac.uk/138128/17/jco.18.01314.pdf
https://eprints.whiterose.ac.uk/138128/17/jco.18.01314.pdf