Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Toong Seng Tan"'
Autor:
Isaac Ngare, Toong Seng Tan, Mako Toyoda, Takeo Kuwata, Soichiro Takahama, Eriko Nakashima, Naoya Yamasaki, Chihiro Motozono, Teruhisa Fujii, Rumi Minami, Godfrey Barabona, Takamasa Ueno
Publikováno v:
Viruses, Vol 16, Iss 4, p 555 (2024)
People living with HIV (PLWH) could be at risk of blunted immune responses to COVID-19 vaccination. We investigated factors associated with neutralizing antibody (NAb) responses against SARS-CoV-2 and variants of concern (VOCs), following two-dose an
Externí odkaz:
https://doaj.org/article/d9b177832abd4f37a6f87ecae205625e
Autor:
Chihiro Motozono, Mako Toyoda, Toong Seng Tan, Hiroshi Hamana, Yoshihiko Goto, Yoshiki Aritsu, Yusuke Miyashita, Hiroyuki Oshiumi, Kimitoshi Nakamura, Seiji Okada, Keiko Udaka, Mizuki Kitamatsu, Hiroyuki Kishi, Takamasa Ueno
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Mutations in the spike of SARS-CoV-2 can result in the escape of the neutralising antibody response but may retain susceptibility to the cellular immune response. Here the authors show the G446S mutation in the spike protein of Omicron BA.1 is associ
Externí odkaz:
https://doaj.org/article/8c5c5a990c0e4b02b5f94e360a145608
Autor:
Mako Toyoda, Toong Seng Tan, Chihiro Motozono, Godfrey Barabona, Akiko Yonekawa, Nobuyuki Shimono, Rumi Minami, Yoji Nagasaki, Yusuke Miyashita, Hiroyuki Oshiumi, Kimitoshi Nakamura, Shuzo Matsushita, Takeo Kuwata, Takamasa Ueno
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Neutralizing potency of humoral immune responses induced by prior infection or vaccination is vital for protecting of individuals and population against severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2). However, the emerg
Externí odkaz:
https://doaj.org/article/37968d628b524c769370eace706954a2
Autor:
Izumi Kimura, Daichi Yamasoba, Hesham Nasser, Jiri Zahradnik, Yusuke Kosugi, Jiaqi Wu, Kayoko Nagata, Keiya Uriu, Yuri L. Tanaka, Jumpei Ito, Ryo Shimizu, Toong Seng Tan, Erika P. Butlertanaka, Hiroyuki Asakura, Kenji Sadamasu, Kazuhisa Yoshimura, Takamasa Ueno, Akifumi Takaori-Kondo, Gideon Schreiber, Mako Toyoda, Kotaro Shirakawa, Takashi Irie, Akatsuki Saito, So Nakagawa, Terumasa Ikeda, Kei Sato
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105720- (2022)
Summary: Recent studies have revealed the unique virological characteristics of Omicron, particularly those of its spike protein, such as less cleavage efficacy in cells, reduced ACE2 binding affinity, and poor fusogenicity. However, it remains uncle
Externí odkaz:
https://doaj.org/article/68c61f21418441b58860e4f5398388dc
Autor:
Seiya Ozono, Yanzhao Zhang, Hirotaka Ode, Kaori Sano, Toong Seng Tan, Kazuo Imai, Kazuyasu Miyoshi, Satoshi Kishigami, Takamasa Ueno, Yasumasa Iwatani, Tadaki Suzuki, Kenzo Tokunaga
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
SARS-CoV-2 D614G spike protein mutation is one of the predominant circulating vital mutants. Here, Ozono et al. demonstrate that D614G mutation increases in vitro cell entry by acquiring higher affinity to ACE2.
Externí odkaz:
https://doaj.org/article/acf66950162a40c68bcc2ed12d14299c
Autor:
George P. Judicate, Godfrey Barabona, Doreen Kamori, Macdonald Mahiti, Toong Seng Tan, Seiya Ozono, Amina Shaban Mgunya, Takeo Kuwata, Shuzo Matsushita, Bruno Sunguya, Eligius Lyamuya, Kenzo Tokunaga, Takamasa Ueno
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
HIV human immunodeficiency virus type I (HIV-1) entry inhibitor potency is dependent on viral co-receptor tropisms and thereby tropism determination is clinically important. However, phenotypic tropisms of HIV-1 non-B subtypes have been poorly invest
Externí odkaz:
https://doaj.org/article/499c7fa3d48e4fb5b497bd6d6ae2e7af
Autor:
Toong Seng Tan, Mako Toyoda, Hirotaka Ode, Godfrey Barabona, Hiroshi Hamana, Mizuki Kitamatsu, Hiroyuki Kishi, Chihiro Motozono, Yasumasa Iwatani, Takamasa Ueno
Publikováno v:
J Virol
Mutations at spike protein L452 are recurrently observed in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOC), including omicron lineages. It remains elusive how amino acid substitutions at L452 are selected in VO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9ddba75c400136af8a96bcdf7a75c87
https://doi.org/10.1128/jvi.01737-22
https://doi.org/10.1128/jvi.01737-22
Autor:
Toong Seng Tan, Mako Toyoda, Hirotaka Ode, Godfrey Barabona, Hiroshi Hamana, Mizuki Kitamatsu, Hiroyuki Kishi, Chihiro Motozono, Yasumasa Iwatani, Takamasa Ueno
Publikováno v:
Journal of Virology. 96
In a span of less than 3 years since the declaration of the coronavirus pandemic, numerous SARS-CoV-2 variants of concern have emerged all around the globe, fueling a surge in the number of cases and deaths that caused severe strain on the health car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::093e173599fada85a393a4e0a27af557
https://doi.org/10.1128/jvi.01162-22
https://doi.org/10.1128/jvi.01162-22
Autor:
Chihiro Motozono, Mako Toyoda, Toong Seng Tan, Hiroshi Hamana, Yoshiki Aritsu, Yusuke Miyashita, Hiroyuki Oshiumi, Kimitoshi Nakamura, Seiji Okada, Keiko Udaka, Mizuki Kitamatsu, Hiroyuki Kishi, Takamasa Ueno
Although the Omicron variant of the SARS-CoV-2 virus is resistant to neutralizing antibodies, it retains susceptibility to cellular immunity. Here, we characterized vaccine-induced T cells specific for various SARS-CoV-2 variants and identified HLA-A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89cc85fc48b817a51dd9ac519b59476f
https://doi.org/10.1101/2022.04.17.488095
https://doi.org/10.1101/2022.04.17.488095
Autor:
Macdonald Mahiti, Doreen Kamori, Bruno F. Sunguya, Toong Seng Tan, Kenzo Tokunaga, Takeo Kuwata, Shuzo Matsushita, Eligius Lyamuya, Amina Shaban Mgunya, Takamasa Ueno, Godfrey Barabona, Seiya Ozono, George P. Judicate
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, Vol 12 (2021)
Frontiers in Microbiology, Vol 12 (2021)
HIV human immunodeficiency virus type I (HIV-1) entry inhibitor potency is dependent on viral co-receptor tropisms and thereby tropism determination is clinically important. However, phenotypic tropisms of HIV-1 non-B subtypes have been poorly invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b6fa1317d4b75ad05ed9de41cc614c
https://pubmed.ncbi.nlm.nih.gov/34305873
https://pubmed.ncbi.nlm.nih.gov/34305873