Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Toomas Runnel"'
Autor:
Freddy Lättekivi, Külli Kingo, Gemma Carreras-Badosa, Beate Rückert, Toomas Runnel, Mario Plaas, Sulev Kõks, Jaanika Kärner, Cezmi A. Akdis, Ana Rebane
Publikováno v:
Allergy. 73:2400-2403
Background: Atopic dermatitis (AD) is a chronic and complex inflammatory skin disease. At least two AD subtypes have been described: allergic (characterized by Type‐2‐cell‐mediated immunity and increased immunoglobulin E [IgE]) and non‐allerg
Autor:
Egon Urgard, Helen Vaher, Gemma Carreras Badosa, Alar Aab, Kristi Abram, Bret Kaldvee, Ana Rebane, Julia Maslovskaja, Tarmo Annilo, Cezmi A. Akdis, Toomas Runnel, Külli Kingo, Liisi Raam, Eric R. Tkaczyk, Toivo Maimets
Publikováno v:
Allergy
Background miR-10a-5p has been shown to regulate cancer cell proliferation and invasiveness and endothelial cell inflammatory responses. The function of miR-10a-5p in the skin has not been previously studied. The aim of the current study was to exami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3432a2ad9832dcdd7bedd9cc4d4e907b
https://doi.org/10.5167/uzh-184083
https://doi.org/10.5167/uzh-184083
Autor:
Richard C. Trembath, H. Hermann, Alar Aab, Michael Weichenthal, Kristi Abram, Ana Rebane, Lam C. Tsoi, Mark Boldin, Beate Rückert, Ele Prans, Paulina Wawrzyniak, Egon Urgard, Ulrich Mrowietz, Jonathan Barker, Toomas Runnel, Liisi Šahmatova, Julia Maslovskaja, James T. Elder, Eric R. Tkaczyk, Uku Haljasorg, Kai Kisand, Cezmi A. Akdis, Pärt Peterson, Maire Karelson, Nathaniel Magilnick, Elke Rodriguez, Külli Kingo, Hansjörg Baurecht, Paula Reemann, Christian Gieger, Bret Kaldvee, Stephan Weidinger, Andre Franke
Publikováno v:
Hermann, H, Runnel, T, Aab, A, Baurecht, H, Rodriguez, E, Magilnick, N, Urgard, E, Šahmatova, L, Prans, E, Maslovskaja, J, Abram, K, Karelson, M, Kaldvee, B, Reemann, P, Haljasorg, U, Rückert, B, Wawrzyniak, P, Weichenthal, M, Mrowietz, U, Franke, A, Gieger, C, Barker, J, Trembath, R, Tsoi, L C, Elder, J T, Tkaczyk, E R, Kisand, K, Peterson, P, Kingo, K, Boldin, M, Weidinger, S, Akdis, C A & Rebane, A 2017, ' miR-146b probably assists miRNA-146a in the suppression of keratinocyte proliferation and inflammatory responses in psoriasis ', Journal of Investigative Dermatology . https://doi.org/10.1016/j.jid.2017.05.012
J. Invest. Dermatol. 137, 1945-1954 (2017)
J. Invest. Dermatol. 137, 1945-1954 (2017)
miR-146a inhibits inflammatory responses in human keratinocytes and in different mouse models of skin inflammation. Little is known about the role of miR-146b in the skin. In this study, we confirmed the increased expression of miR-146a and miR-146b
Autor:
Julia Maslovskaja, Anet Kivihall, Liisi Raam, Kristi Abram, Helen Vaher, Külli Kingo, Ana Rebane, Bret Kaldvee, Ele Prans, Ulrich Mrowietz, Toomas Runnel, Stephan Weidinger
Publikováno v:
Experimental dermatologyREFERENCES. 29(1)
Psoriasis is a chronic inflammatory skin disease with numerous involved factors. miR-146a and miR-146b (miR-146a/b) are anti-inflammatory miRNAs that are increased in psoriatic skin. SERPINB2 has been shown to be upregulated in the inflammation and i
Autor:
Ana Rebane, Egon Urgard, Mariliis Klaas, Eric R. Tkaczyk, Kent Langel, Janeli Viil, Toivo Maimets, Viljar Jaks, Ülo Langel, Kärt Padari, Toomas Runnel, Annely Lorents, Margus Pooga, Külli Kingo
Publikováno v:
Journal of Controlled Release. 235:195-204
The skin is a difficult to access tissue for efficient delivery of large and/or charged macromolecules, including therapeutic DNA and RNA oligonucleotides. Cell-penetrating peptide PepFect6 (PF6) has been shown to be suitable transport vehicle for si
Autor:
Jaanika Kärner, Ana Rebane, Marcin Wawrzyniak, Külli Kingo, Toomas Runnel, Cezmi A. Akdis, Alan Altraja, Kai Kisand, Mübeccel Akdis, A. Aints, Stoyan Tankov
Publikováno v:
Europe PubMed Central
Background IL-22- and IL-17-producing T cells have important roles in allergic diseases. MicroRNAs (miRNAs) are posttranscriptional regulators of gene expression and modulate numerous biological processes. Little is known about the functions of miRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5611ae08af1ad3743855b7fa6c0f54bf
https://www.zora.uzh.ch/id/eprint/129740/
https://www.zora.uzh.ch/id/eprint/129740/
Autor:
Hedi Peterson, Jaak Vilo, Liina Tserel, Maire Pihlap, Toomas Runnel, Lairi Bakhoff, Raivo Kolde, Kai Kisand, Ana Rebane, Pärt Peterson
Publikováno v:
Journal of Biological Chemistry. 286:26487-26495
Dendritic cells (DCs) and macrophages (MFs) are important multifunctional immune cells. Like other cell types, they express hundreds of different microRNAs (miRNAs) that are recently discovered post-transcriptional regulators of gene expression. Here
Autor:
Egon Urgard, Eric R. Tkaczyk, H. Hermann, Külli Kingo, Alar Aab, Kristi Abram, Bret Kaldvee, Toomas Runnel, Ana Rebane, L. ahmatova, Cezmi A. Akdis
Publikováno v:
Journal of Investigative Dermatology. 138:B15
Autor:
Bret Kaldvee, Kristi Abram, Toomas Runnel, S. Weidinger, H. Hermann, Ana Rebane, Liisi Šahmatova, E. Prants, Külli Kingo, Ulrich Mrowietz
Publikováno v:
Journal of Investigative Dermatology. 137:S259
Autor:
Maya Zimmermann, Nikoletta Nagy, Beate Rückert, Külli Kingo, Mario Plaas, Mei Li, Julia Maslovskaja, Angela Treis, Alar Aab, Cezmi A. Akdis, Uku Haljasorg, H. Hermann, Triin Erm, Lajos Kemény, Maire Pihlap, Jaanika Kärner, Mark Boldin, Ana Rebane, Toomas Runnel
Publikováno v:
Journal of Allergy and Clinical Immunology
Europe PubMed Central
ResearcherID
Journal of Allergy and Clinical Immunology, Elsevier, 2014, 134 (4), pp.836-847.e11. ⟨10.1016/j.jaci.2014.05.022⟩
Europe PubMed Central
ResearcherID
Journal of Allergy and Clinical Immunology, Elsevier, 2014, 134 (4), pp.836-847.e11. ⟨10.1016/j.jaci.2014.05.022⟩
Background Chronic skin inflammation in atopic dermatitis (AD) is associated with elevated expression of proinflammatory genes and activation of innate immune responses in keratinocytes. microRNAs (miRNAs) are short, single-stranded RNA molecules tha