Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Toomas Mets"'
Autor:
Karin Ernits, Chayan Kumar Saha, Tetiana Brodiazhenko, Bhanu Chouhan, Aditi Shenoy, Julian J Duque-Pedraza, Veda Bojar, Jose A Nakamoto, Tatsuaki Kurata, Artyom Egorov, Lena Shyrokova, Marcus J. O. Johansson, Toomas Mets, Aytan Rustamova, Jelisaveta Dzigurski, Tanel Tenson, Abel Garcia-Pino, Arne Elofsson, Vasili Hauryliuk, Gemma Catherine Atkinson
Toxin-antitoxin (TA) systems are a large group of small genetic modules found in prokaryotes and their mobile genetic elements. Type II TAs are encoded as bicistronic (two-gene) operons that encode two proteins: a toxin and neutralising antitoxin. Us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19bb730b2ee9c3d9501b3ecede3018f2
https://doi.org/10.1101/2023.03.22.533649
https://doi.org/10.1101/2023.03.22.533649
Autor:
Janani Durairaj, Andrew M. Waterhouse, Toomas Mets, Tetiana Brodiazhenko, Minhal Abdullah, Gabriel Studer, Mehmet Akdel, Antonina Andreeva, Alex Bateman, Tanel Tenson, Vasili Hauryliuk, Torsten Schwede, Joana Pereira
Driven by the development and upscaling of fast genome sequencing and assembly pipelines, the number of protein-coding sequences deposited in public protein sequence databases is increasing exponentially. Recently, the dramatic success of deep learni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::786c91e64c9be50392c773c3fedf4cda
https://doi.org/10.1101/2023.03.14.532539
https://doi.org/10.1101/2023.03.14.532539
Autor:
Tatsuaki, Kurata, Chayan Kumar, Saha, Jessica A, Buttress, Toomas, Mets, Tetiana, Brodiazhenko, Kathryn J, Turnbull, Ololade F, Awoyomi, Sofia Raquel Alves, Oliveira, Steffi, Jimmy, Karin, Ernits, Maxence, Delannoy, Karina, Persson, Tanel, Tenson, Henrik, Strahl, Vasili, Hauryliuk, Gemma C, Atkinson
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(6)
Toxin-antitoxin (TA) gene pairs are ubiquitous in microbial chromosomal genomes and plasmids as well as temperate bacteriophages. They act as regulatory switches, with the toxin limiting the growth of bacteria and archaea by compromising diverse esse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::44c8344a78a0e48975dd3dfc8a88427d
https://pubmed.ncbi.nlm.nih.gov/35121656
https://pubmed.ncbi.nlm.nih.gov/35121656
Autor:
Anton Paier, Toomas Mets, David Schryer, Tanel Tenson, Jaanus Remme, Markus Lippus, Ülo Maiväli, Aivar Liiv, Villu Kasari, Niilo Kaldalu
Publikováno v:
RNA Biology
The endoribonuclease toxins of the E. coli toxin-antitoxin systems arrest bacterial growth and protein synthesis by targeting cellular mRNAs. As an exception, E. coli MazF was reported to cleave also 16S rRNA at a single site and separate an anti-Shi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85882fccdb8681871b84aded994220f4
https://doi.org/10.1080/15476286.2016.1259784
https://doi.org/10.1080/15476286.2016.1259784
Publikováno v:
Biochimie
MazEF and MqsRA are toxin-antitoxin systems, where the toxins MazF and MqsR sequence-specifically cleave single-stranded RNA, thereby shutting down protein synthesis and cell growth. However, it has been proposed that MazF functions in a highly speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d17e62a35c396cb8a65f63922e079c63
https://pubmed.ncbi.nlm.nih.gov/30315853
https://pubmed.ncbi.nlm.nih.gov/30315853
Publikováno v:
BMC Microbiology
Background Bacterial toxin-antitoxin (TA) systems are formed by potent regulatory or suicide factors (toxins) and their short-lived inhibitors (antitoxins). Antitoxins are DNA-binding proteins and auto-repress transcription of TA operons. Transcripti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94abbfc2ec62b0e0b4e40c438088fa8c
http://europepmc.org/articles/PMC3598666
http://europepmc.org/articles/PMC3598666