Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Toolsie Ramlal"'
Autor:
Romel SOMWAR, David Y. KIM, Gary SWEENEY, Carol HUANG, Wenyan NIU, Crina LADOR, Toolsie RAMLAL, Amira KLIP
Publikováno v:
Biochemical Journal. 359:639-649
We previously reported that SB203580, an inhibitor of p38 mitogen-activated protein kinase (p38 MAPK), attenuates insulin-stimulated glucose uptake without altering GLUT4 translocation. These results suggested that insulin might activate GLUT4 via a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cb1cb72becd6e0c9a185e66f1928e78
https://doi.org/10.1042/bj3590639
https://doi.org/10.1042/bj3590639
Autor:
Toolsie Ramlal, Daniel Konrad, Amira Klip, Romel Somwar, Michiko Hayashi, Gary Sweeney, Karen Yaworsky
Publikováno v:
Diabetes. 50:1464-1471
The cofactor of mitochondrial dehydrogenase complexes and potent antioxidant alpha-lipoic acid has been shown to lower blood glucose in diabetic animals. alpha-Lipoic acid enhances glucose uptake and GLUT1 and GLUT4 translocation in 3T3-L1 adipocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3d7ae3f21a3df392f109eb3a10dd7d3
https://doi.org/10.2337/diabetes.50.6.1464
https://doi.org/10.2337/diabetes.50.6.1464
Publikováno v:
Journal of Biological Chemistry. 274:10071-10078
The precise mechanisms underlying insulin-stimulated glucose transport still require investigation. Here we assessed the effect of SB203580, an inhibitor of the p38 MAP kinase family, on insulin-stimulated glucose transport in 3T3-L1 adipocytes and L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb90a4e67f1ace20826e4ce9c26c4fca
https://doi.org/10.1074/jbc.274.15.10071
https://doi.org/10.1074/jbc.274.15.10071
Publikováno v:
Endocrinology. 138:1029-1034
vp165, a recently described member of the family of zinc-dependent membrane aminopeptidases, is a major constituent of glucose transporter-4 (GLUT4)-containing vesicles in adipocytes and skeletal muscle. Here we show that vp165 is expressed in L6 myo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acafa9670f563a882922a1e24663c6db
https://doi.org/10.1210/endo.138.3.5010
https://doi.org/10.1210/endo.138.3.5010
Autor:
H S Ewart, Amira Klip, Theodoros Tsakiridis, H. J. Tritschler, Allen Volchuk, D. E. Estrada, Toolsie Ramlal
Publikováno v:
Diabetes. 45:1798-1804
Thioctic acid (α-lipoic acid), a natural cofactor in dehydrogenase complexes, is used in Germany in the treatment of symptoms of diabetic neuropathy. Thioctic acid improves insulin-responsive glucose utilization in rat muscle preparations and during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d920f75701d8c2ac765bdc467ab85b1
https://doi.org/10.2337/diab.45.12.1798
https://doi.org/10.2337/diab.45.12.1798
Autor:
L. Lavoie, André Marette, L. Dombrowski, Amira Klip, Denis Roy, J. L. Carpentier, Toolsie Ramlal, P. Martn-Vasallo
Publikováno v:
American Journal of Physiology-Cell Physiology. 270:C1421-C1429
We have previously shown that an acute insulin treatment induces redistribution of the alpha 2- and beta 1- isoforms of the Na(+)-K(+)-ATPase from intracellular membranes to plasma membranes detected on subcellular fractionation of mixed muscles and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b0de9036342915a6ff6dc8e7d6a6e1a
https://doi.org/10.1152/ajpcell.1996.270.5.c1421
https://doi.org/10.1152/ajpcell.1996.270.5.c1421
Publikováno v:
Biochemical and Biophysical Research Communications. 213:462-468
Syntaxins are a family of membrane proteins believed to participate in docking/fusing of arriving vesicles during membrane sorting and secretion. Of the six mammalian syntaxins known, only brain syntaxin 1A/1B has been biochemically characterized in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3940513cedd6543b7b632d7989c7bda4
https://doi.org/10.1006/bbrc.1995.2154
https://doi.org/10.1006/bbrc.1995.2154
Publikováno v:
Biochemical and Biophysical Research Communications. 199:662-670
Murine models of insulin resistance and diabetes are versatile and have been used to investigate genetic and metabolic disorders. However, the principal assays to assess insulin action, i.e., the euglycemic-hyperinsulinemic clamp and subcellular dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ee40c851218ae5f076ed9d24a650cd4
https://doi.org/10.1006/bbrc.1994.1279
https://doi.org/10.1006/bbrc.1994.1279
Publikováno v:
FEBS Letters. 328:253-258
Hindlimb skeletal muscles of the rat express two isoforms of the alpha (alpha 1 and alpha 2) and two isoforms of the beta (beta 1 and beta 2) subunits of the Na+,K(+)-ATPase. Because several muscles constitute the hindlimb, we investigated if specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d6cd9dd77b9b14f59d12345c996954
https://doi.org/10.1016/0014-5793(93)80938-q
https://doi.org/10.1016/0014-5793(93)80938-q
Publikováno v:
Journal of Applied Physiology. 70:1593-1600
Hypoxia caused a progressive cytochalasin B-inhibitable increase in the rate of 3-O-methylglucose transport in rat epitrochlearis muscles to a level approximately six-fold above basal. Muscle ATP concentration was well maintained during hypoxia, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b38e6ab26a69a58d8254c4c7613e60fa
https://doi.org/10.1152/jappl.1991.70.4.1593
https://doi.org/10.1152/jappl.1991.70.4.1593