Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Tools for Protein Science"'
Autor:
Janet M. Thornton, Roman A. Laskowski
Publikováno v:
Protein Science : A Publication of the Protein Society
The PDBsum web server provides structural analyses of the entries in the Protein Data Bank (PDB). Two recent additions are described here. The first is the detailed analysis of the SARS‐CoV‐2 virus protein structures in the PDB. These include the
Autor:
Gabriel Wright, Tijana Milenkovic, Patricia L. Clark, Scott J. Emrich, Anabel Rodriguez, Jun Li
Publikováno v:
Protein Sci
There is a growing appreciation that synonymous codon usage, although historically regarded as phenotypically silent, can instead alter a wide range of mechanisms related to functional protein production, a term we use here to describe the net effect
Publikováno v:
Protein Sci
Cellular protrusions, invaginations, and many intracellular organelles have strongly curved membrane regions. Transmembrane and peripheral membrane proteins that induce, sense, or stabilize such regions cannot be properly fitted into a single flat bi
Autor:
Stephen K. Burley, Zukang Feng, John D. Westbrook, Andrej Sali, Justin W Flatt, Rachel Kramer Green, Chenghua Shao, Sai J. Ganesan, Sutapa Ghosh, Brinda Vallat, David S. Goodsell, Jeremy Henry, Christine Zardecki, Joan Segura, Ezra Peisach, Charmi Bhikadiya, Catherine L. Lawson, Jose M. Duarte, Brian P. Hudson, Irina Persikova, Chunxiao Bi, Gregg V. Crichlow, Robert Lowe, Monica Sekharan, Jasmine Young, Shamara Whetstone, Li Chen, Vladimir Guranovic, Yu-He Liang, Dennis W Piehl, Maryam Fayazi, Maria Voigt, Sebastian Bittrich, Shuchismita Dutta, Yana Rose
Publikováno v:
Protein Sci
The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB), funded by the US National Science Foundation, National Institutes of Health, and Department of Energy, has served structural biologists and Protein Data Bank (PDB)
Autor:
Gert-Jan Bekker, Takahiro Kudou, Yasuyo Ikegawa, Takeshi Kawabata, Masashi Yokochi, Genji Kurisu, Hirofumi Suzuki, Kei Yura, Toshimichi Fujiwara, Takeshi Iwata
Publikováno v:
Protein Science : A Publication of the Protein Society
Protein Data Bank Japan (PDBj), a founding member of the worldwide Protein Data Bank (wwPDB) has accepted, processed and distributed experimentally determined biological macromolecular structures for 20 years. During that time, we have continuously m
Autor:
Robert Lowe, Shuchismita Dutta, Christine Zardecki, Maria Voigt, Stephen K. Burley, David S. Goodsell
Publikováno v:
Protein Sci
The Protein Data Bank (PDB) archive is a rich source of information in the form of atomic-level 3D structures of biomolecules experimentally determined using macromolecular crystallography (MX), nuclear magnetic resonance (NMR) spectroscopy, and elec
Autor:
Martin Zacharias
Publikováno v:
Protein Science : A Publication of the Protein Society
In order to generate protein assemblies with a desired function, the rational design of protein–protein binding interfaces is of significant interest. Approaches based on random mutagenesis or directed evolution may involve complex experimental sel
Publikováno v:
Protein Sci
The antimicrobial peptide database (APD) has served the antimicrobial peptide field for 18 years. Because it is widely used in research and education, this article documents database milestones and key events that have transformed it into the current
Autor:
Ian J. Fucci, R. Andrew Byrd
Publikováno v:
Protein Sci
Nuclear magnetic resonance (NMR) provides site specific information on local environments through chemical shifts. NMR is widely used in the study of proteins, ranging from determination of three-dimensional (3D) structures to characterizing dynamics
Autor:
Tucker L Apgar, Charles R. Sanders
Publikováno v:
Protein Sci
A compendium is presented of inherited monogenic disorders that have a prevalence of >1:20,000 in the human population, along with their causative genes and encoded proteins. “Simple” monogenic diseases are those for which the clinical features a