Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Tonya Wallace"'
Autor:
Cecily Choy, Joseph Chen, Jiangyuan Li, D. Travis Gallagher, Jian Lu, Daichao Wu, Ainslee Zou, Humza Hemani, Beverly A. Baptiste, Emily Wichmann, Qian Yang, Jeffrey Ciffelo, Rui Yin, Julia McKelvy, Denise Melvin, Tonya Wallace, Christopher Dunn, Cuong Nguyen, Chee W. Chia, Jinshui Fan, Jeannie Ruffolo, Linda Zukley, Guixin Shi, Tomokazu Amano, Yang An, Osorio Meirelles, Wells W. Wu, Chao-Kai Chou, Rong-Fong Shen, Richard A. Willis, Minoru S. H. Ko, Yu-Tsueng Liu, Supriyo De, Brian G. Pierce, Luigi Ferrucci, Josephine Egan, Roy Mariuzza, Nan-Ping Weng
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract The resolution of SARS-CoV-2 replication hinges on cell-mediated immunity, wherein CD8+ T cells play a vital role. Nonetheless, the characterization of the specificity and TCR composition of CD8+ T cells targeting non-spike protein of SARS-C
Externí odkaz:
https://doaj.org/article/963224e732b44fa8b3d0805dabc27063
Autor:
Jian Lu, Guobing Chen, Arina Sorokina, Thomas Nguyen, Tonya Wallace, Cuong Nguyen, Christopher Dunn, Stephanie Wang, Samantha Ellis, Guixin Shi, Julia McKelvey, Alexei Sharov, Yu-Tsueng Liu, Jonathan Schneck, Nan-ping Weng
Publikováno v:
Immunity & Ageing, Vol 19, Iss 1, Pp 1-14 (2022)
Abstract Background Cytomegalovirus (CMV) infection leads to effector memory CD8+ T cell expansion and is associated with immune dysfunction in older adults. However, the molecular alterations of CMV-specific CD8+ T cells in CMV infected healthy youn
Externí odkaz:
https://doaj.org/article/f2e69a5f4c7d428ead79b2f5ba00c19e
Autor:
Roshni Roy, Pei-Lun Kuo, Julián Candia, Dimitra Sarantopoulou, Ceereena Ubaida-Mohien, Dena Hernandez, Mary Kaileh, Sampath Arepalli, Amit Singh, Arsun Bektas, Jaekwan Kim, Ann Z Moore, Toshiko Tanaka, Julia McKelvey, Linda Zukley, Cuong Nguyen, Tonya Wallace, Christopher Dunn, William Wood, Yulan Piao, Christopher Coletta, Supriyo De, Jyoti Sen, Nan-ping Weng, Ranjan Sen, Luigi Ferrucci
Publikováno v:
eLife, Vol 12 (2023)
Age-associated DNA methylation in blood cells convey information on health status. However, the mechanisms that drive these changes in circulating cells and their relationships to gene regulation are unknown. We identified age-associated DNA methylat
Externí odkaz:
https://doaj.org/article/d686b4020d774313aa1c545d7788c07b
Single-cell analysis of skeletal muscle macrophages reveals age-associated functional subpopulations
Autor:
Linda K Krasniewski, Papiya Chakraborty, Chang-Yi Cui, Krystyna Mazan-Mamczarz, Christopher Dunn, Yulan Piao, Jinshui Fan, Changyou Shi, Tonya Wallace, Cuong Nguyen, Isabelle A Rathbun, Rachel Munk, Dimitrios Tsitsipatis, Supriyo De, Payel Sen, Luigi Ferrucci, Myriam Gorospe
Publikováno v:
eLife, Vol 11 (2022)
Tissue-resident macrophages represent a group of highly responsive innate immune cells that acquire diverse functions by polarizing toward distinct subpopulations. The subpopulations of macrophages that reside in skeletal muscle (SKM) and their chang
Externí odkaz:
https://doaj.org/article/f5d9b918022644cabc8de125fed6a2a3
Autor:
Roshni Roy, Pei-Lun Kuo, Julián Candia, Dimitra Sarantopoulou, Ceereena Ubaida-Mohien, Dena Hernandez, Mary Kaileh, Sampath Arepalli, Amit Singh, Arsun Bektas, Jaekwan Kim, Ann Zenobia Moore, Toshiko Tanaka, Julia McKelvey, Linda Zukley, Cuong Nguyen, Tonya Wallace, Christopher Dunn, William Wood, Yulan Piao, Christopher Coletta, Supriyo De, Jyoti Misra Sen, Nan-ping Weng, Ranjan Sen, Luigi Ferrucci
Age-associated DNA methylation in blood cells convey information on health status. However, the mechanisms that drive these changes in circulating cells and their relationships to gene regulation are unknown. We identified age-associated DNA methylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48375812d9541b74e205fcd205a7d98f
https://doi.org/10.1101/2023.01.23.525162
https://doi.org/10.1101/2023.01.23.525162
Autor:
Linda K Krasniewski, Papiya Chakraborty, Chang-Yi Cui, Krystyna Mazan-Mamczarz, Christopher Dunn, Yulan Piao, Jinshui Fan, Changyou Shi, Tonya Wallace, Cuong Nguyen, Isabelle A Rathbun, Rachel Munk, Dimitrios Tsitsipatis, Supriyo De, Payel Sen, Luigi Ferrucci, Myriam Gorospe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c962d893ba0885090c859fd23641e6d
https://doi.org/10.7554/elife.77974.sa2
https://doi.org/10.7554/elife.77974.sa2
Autor:
Sören Boller, Tonya Wallace, Christopher E. Coletta, Dimitra Sarantopoulou, Julia McKelvey, Yulan Piao, Luigi Ferrucci, Cuong Q. Nguyen, Sampath Arepalli, Benjamin D. Shapiro, Christopher A. Dunn, Mary Kaileh, Ranjan Sen, Dena G. Hernandez, Linda Zukley, Nan-ping Weng, Arsun Bektas, Alexis Battle, Roshni Roy, Ann Zenobia Moore, Senthilkumar Ramamoorthy, Supriyo De, Toshiko Tanaka, Kevin G. Becker, Rudolf Grosschedl, Amit Singh, William H. Wood, Jaekwan Kim, Jyoti Misra Sen, Robert P. Wersto
Publikováno v:
Immunity
Epigenetic reprogramming underlies specification of immune cell lineages, but patterns that uniquely define immune cell types and the mechanisms by which they are established remain unclear. Here, we identified lineage-specific DNA methylation signat
Autor:
Cecily Choy, Jian Lu, Jiangyuan Li, Humza Hemani, Joseph Chen, Ana Lustig, Julia McKelvey, Denise Melvin, Jeannie Ruffolo, Linda Zukley, Tonya Wallace, Christopher Dunn, Cuong Nguyen, Jinshui Fan, Supriyo De, Chee Chia, Luigi Ferrucci, Josephine Egan, Nan-ping Weng
Publikováno v:
The Journal of Immunology. 208:125.19-125.19
COVID-19, an infectious disease caused by SARS-CoV-2, has given rise to the current global pandemic. Despite the number of infections nearing 300 million people worldwide, CD8+ T cells against SARS-CoV-2 in COVID-19 convalescent, vaccinated, and heal
Autor:
Amit K Singh, Roshni Roy, Mary Kaileh, Dimitra Sarantopoulou, Dena Hernandez, Sampath Arepalli, Arsun Bektas, Jaekwan Kim, Julia McKelevy, Linda Zukely, Christopher Dunn, Cuong Nguyen, Tonya Wallace, William Wood, Yulan Piao, Supriyo De, Jyoti Misra Sen, Nan-ping Weng, Luigi Ferrucci, Ranjan Sen
Publikováno v:
The Journal of Immunology. 208:168.11-168.11
Long-term immunity against infections and effective response to vaccination are dependent on remarkable and unique feature of lymphocytes referred as “memory generation”. Despite having multiple mice studies focused on naïve to memory transition
Autor:
Cecily Choy, Jian Lu, Jiangyuan Li, Christopher Dunn, Tonya Wallace, Cuong Nguyen, Julia McKelvey, Denise Melvin, Josephine Egan, Nan-Ping Weng
Publikováno v:
The Journal of Immunology. 206:103.16-103.16
COVID-19, an infectious disease caused by SARS-CoV-2, has caused the current global pandemic. Despite the number of infections nearing 100 million people worldwide, the CD8+ T cells against SARS-CoV-2 in healthy adults as well as in convalescent COVI