Erythroid-specific transcriptional changes in PBMCs from pulmonary hypertension patients.

Autor: Chris Cheadle, Alan E Berger, Stephen C Mathai, Dmitry N Grigoryev, Tonya N Watkins, Yumiko Sugawara, Sangjucta Barkataki, Jinshui Fan, Meher Boorgula, Laura Hummers, Ari L Zaiman, Reda Girgis, Michael A McDevitt, Roger A Johns, Frederick Wigley, Kathleen C Barnes, Paul M Hassoun

Publikováno v: PLoS ONE, Vol 7, Iss 4, p e34951 (2012)

Gene expression profiling of peripheral blood mononuclear cells (PBMCs) is a powerful tool for the identification of surrogate markers involved in disease processes. The hypothesis tested in this study was that chronic exposure of PBMCs to a hyperten

Externí odkaz: https://doaj.org/article/10f0172ce73240efb638308f089a07da

Abstract 756: Comprehensive NGS-based reference materials for variant detection in lymphoid cancer

Autor: Tonya N. Watkins, Benedicta Forson, Dana Ruminski Lowe, Yves Konigshofer, Catherine Huang, Omoshile Clement, Bharathi Anekella

Publikováno v: Cancer Research. 82:756-756

Next Generation Sequencing (NGS) is an important technology to identify genetic changes involved in lymphoid malignancies. Genome-level understanding of these changes can aid in diagnosis, prognosis, and therapy selection. Cancer biopsies are often p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c23783df870463b7649b601365afbc3d
https://doi.org/10.1158/1538-7445.am2022-756

Interacting post-muscarinic receptor signaling pathways potentiate matrix metalloproteinase-1 expression and invasion of human colon cancer cells

Autor: Shien Hu, Kunrong Cheng, Ahmed Chahdi, Neeraj K. Saxena, Anan H. Said, Ameer Abutaleb, Guofeng Xie, Panjamurthy Kuppusamy, Jean-Pierre Raufman, Tonya N. Watkins

Publikováno v: Biochemical Journal. 474:647-665

M3 muscarinic receptor (M3R) expression is increased in colon cancer; M3R activation stimulates colon cancer cell invasion via cross-talk with epidermal growth factor receptors (EGFR), post-EGFR activation of mitogen-activated protein kinase (MAPK) e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f41b5e4780bd0e16c968aeb7dd2f1ad6
https://doi.org/10.1042/bcj20160704

Comparative transcriptomics of Aspergillus fumigatus strains upon exposure to human airway epithelial cells

Autor: Scott G. Filler, Julie C. Dunning Hotopp, Tonya N. Watkins, Tracy H. Hazen, Matthew Chung, Vincent M. Bruno, Hong Liu

Publikováno v: Watkins, TN; Liu, H; Chung, M; Hazen, TH; Hotopp, JCD; Filler, SG; et al.(2018). Comparative transcriptomics of Aspergillus fumigatus strains upon exposure to human airway epithelial cells. MICROBIAL GENOMICS, 4(2). doi: 10.1099/mgen.0.000154. UCLA: Retrieved from: http://www.escholarship.org/uc/item/4271m3bp
Microbial Genomics
Microbial genomics, vol 4, iss 2

Aspergillus fumigatus is an opportunistic, ubiquitous, saprophytic mould that can cause severe allergic responses in atopic individuals as well as life-threatening infections in immunocompromised patients. A critical step in the establishment of infe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c3abdcdf8bab1c9235b0e66cc0eec18
http://www.escholarship.org/uc/item/4271m3bp

Tu1903 Potentiating Interactions Between Type-3 Muscarinic Receptor (M3R) Signaling Pathways Augment Matrix Metalloproteinase-1 (MMP1) Expression in Human Colon Cancer Cells

Autor: Jean-Pierre Raufman, Shien Hu, Tonya N. Watkins, Kunrong Cheng, Guofeng Xie, Anan H. Said, Ameer Abutaleb

Publikováno v: Gastroenterology. 148:S-932

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e48492c28c8c8d2c6cb57276dac4f21
https://doi.org/10.1016/s0016-5085(15)33173-5