Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Tonya J, Webb"'
Autor:
Michael S. Lee, Tonya J. Webb
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Cancer immunotherapy aims to unleash the power of the immune system against tumors without the side effects of traditional chemotherapy. Immunotherapeutic methods vary widely, but all follow the same basic principle: overcome the barriers utilized by
Externí odkaz:
https://doaj.org/article/8a013e58eee2482c8a4a4692fedc0f3a
Autor:
Rania H. Younis, Ioana Ghita, Manar Elnaggar, Risa Chaisuparat, Vasileios Ionas Theofilou, Donita Dyalram, Robert A. Ord, Eduardo Davila, Luke J. Tallon, John C. Papadimitriou, Tonya J. Webb, Søren M. Bentzen, Joshua E. Lubek
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Semaphorin 4D (Sema4D) is a glycoprotein that is expressed by several tumors and immune cells. It can function as a membrane bound protein or as a cleaved soluble protein (sSema4D). We sought to investigate the translational potential of plasma sSema
Externí odkaz:
https://doaj.org/article/19cfa04f359047f4b006f3431afea03f
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/56e40ea18dfb4ebcbeec3f0500cb8738
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-14 (2018)
Abstract Tumors develop multiple mechanisms of immune evasion as they progress, with some cancer types being inherently better at ‘hiding’ than others. With an increased understanding of tumor immune surveillance, immunotherapy has emerged as a p
Externí odkaz:
https://doaj.org/article/37fe0918db2e448798acb02a3e167cf6
Autor:
Brandi E. Hobbs, Courtney A. Matson, Vasileios I. Theofilou, Tonya J. Webb, Rania H. Younis, Eileen M. Barry
Publikováno v:
Pathogens, Vol 10, Iss 7, p 799 (2021)
Francisella tularensis (Ft) is a Gram-negative, facultative intracellular bacterium that is a Tier 1 Select Agent of concern for biodefense for which there is no licensed vaccine. A subfamily of 9 Francisella phagosomal transporter (fpt) genes belong
Externí odkaz:
https://doaj.org/article/e73fbda3bfd344ffa0a382046fb61f61
Autor:
Zewde Ingram, Shriya Madan, Jenoy Merchant, Zakiya Carter, Zen Gordon, Gregory Carey, Tonya J. Webb
Publikováno v:
Cells, Vol 10, Iss 6, p 1329 (2021)
Natural killer T (NKT) cells are a unique subset of lymphocytes that recognize lipid antigens in the context of the non-classical class I MHC molecule, CD1d, and serve as a link between the innate and adaptive immune system through their expeditious
Externí odkaz:
https://doaj.org/article/2ae05f4b47fa41dab0bcda9bc734dcdf
Autor:
Tonya J. Webb, Jonathan P. Schneck, Mathias Oelke, Robert L. Giuntoli, Simeon E. Goldblum, Sarah Spiegel, Sarah M. Temkin, Irina V. Tiper
Ovarian cancer associated ascites contains soluble inhibitory factors. The ascites was cleared of cellular debris by centrifugation as previously described (18). (A, B) The ascites was filtered 0.2 micron filter and fractionated- f1: 50. (C) The asci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::280df69edd902461d357cb0ed0f9abe5
https://doi.org/10.1158/1078-0432.22455875.v1
https://doi.org/10.1158/1078-0432.22455875.v1
Autor:
Tonya J. Webb, Jonathan P. Schneck, Mathias Oelke, Robert L. Giuntoli, Simeon E. Goldblum, Sarah Spiegel, Sarah M. Temkin, Irina V. Tiper
The source of GD3 impacts CD1d-mediated antigen presentation.(A) LCD1d cells were treated with GD3 from different sources for 4 hours, then washed extensively and cocultured with NKT cell hybridomas. IL-2 was measured, as an indication of NKT cell ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::799e58147807faa82cbcc2187827ae44
https://doi.org/10.1158/1078-0432.22455872.v1
https://doi.org/10.1158/1078-0432.22455872.v1
Autor:
Jonathan P. Schneck, Mathias Oelke, Christian Kurts, Moriya Tsuji, Ronald L. Schnaar, Christoph Heuser, Pablo H.H. Lopez, Robert L. Giuntoli, Xiangming Li, Tonya J. Webb
PDF file - 225K, Schematic of Ganglioside GD3 and other glycolipids used or referred to in this paper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80a16e1f594710df302e177cd90b1c77
https://doi.org/10.1158/0008-5472.22392759.v1
https://doi.org/10.1158/0008-5472.22392759.v1
Publikováno v:
Cells, Vol 9, Iss 4, p 1030 (2020)
Mantle cell lymphoma (MCL) is an aggressive subtype of non-Hodgkin’s lymphoma. Despite being responsive to combination chemotherapy, median survival remains around 5 years due to high rates of relapse. Sphingolipid metabolism regulates MCL survival
Externí odkaz:
https://doaj.org/article/93ceff6ab84f4f8ab3b509777a80fb8b