Zobrazeno 1 - 4
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pro vyhledávání: '"Tonya Brady"'
Autor:
Steven M. D'Ambrosio, Andrew S. Oberyszyn, Tonya Brady, Ruth E. Gibson-D'Ambrosio, Fredika M. Robertson
Publikováno v:
Environmental and Molecular Mutagenesis. 37:46-54
Chronic exposure of hepatocytes to reactive nitrogen species (RNS) following liver injury and inflammation leads not only to functional and morphological alterations in the liver but also to degenerative liver diseases and hepatocellular carcinoma. P
Publikováno v:
Hepatology Research. 11:188-200
Upon injury, the liver has the capability to replace lost hepatocytes by at least two processes. In the unipotential model hepatocytes exit quiescence after injury and replicate, while in the multipotential model non-parenchymal epithelial cells repl
Publikováno v:
Biochemical and Biophysical Research Communications. 233:545-549
The cytotoxic effects of 3-morpholinosydnonimine (Sin-1) and S-nitroso-N-acetylpenicillamine-amine (SNAP) on replicatively active human hepatocyte cells in culture was determined as a function of oxidant type. Both Sin-1 which yields nitric oxide and
Publikováno v:
Environmental and Molecular Mutagenesis. 29:168-179
O6-Alkylguanine-DNA alkyltransferase (AGT) is responsible for repairing the O6-alkylguanine lesion in DNA. There is wide variation in the levels of AGT between organ and cell types, which appears to correlate with cell and tissue type sensitivity to