Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Tony del Rio"'
Autor:
Beltran Borges, Antonia Varthaliti, Marisa Schwab, Maria T. Clarke, Christopher Pivetti, Nalin Gupta, Cathryn R. Cadwell, Ghiabe Guibinga, Shirley Phillips, Tony Del Rio, Fatih Ozsolak, Denise Imai-Leonard, Lingling Kong, Diana J. Laird, Akos Herzeg, Charlotte J. Sumner, Tippi C. MacKenzie
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 2, Pp 101263- (2024)
Prenatal somatic cell gene therapy (PSCGT) could potentially treat severe, early-onset genetic disorders such as spinal muscular atrophy (SMA) or muscular dystrophy. Given the approval of adeno-associated virus serotype 9 (AAV9) vectors in infants wi
Externí odkaz:
https://doaj.org/article/d01f9d171e174897be32403a75098f3a
Autor:
Ian B. Hogue, Jens B. Bosse, Esteban A. Engel, Julian Scherer, Jiun-Ruey Hu, Tony del Rio, Lynn W. Enquist
Publikováno v:
Viruses, Vol 7, Iss 11, Pp 5933-5961 (2015)
In the nearly two decades since the popularization of green fluorescent protein (GFP), fluorescent protein-based methodologies have revolutionized molecular and cell biology, allowing us to literally see biological processes as never before. Naturall
Externí odkaz:
https://doaj.org/article/449a0e23565a401e90b28ddfad923500
Publikováno v:
PLoS Genetics, Vol 9, Iss 9, p e1003824 (2013)
Lrig proteins are conserved transmembrane proteins that modulate a variety of signaling pathways from worm to humans. In mammals, there are three family members - Lrig1, Lrig2, and Lrig3--that are defined by closely related extracellular domains with
Externí odkaz:
https://doaj.org/article/1e5962314c514c15bec30bdffbec7749
Autor:
Marion M. France, Tony del Rio, Hannah Travers, Erin Raftery, Robert Langer, Giovanni Traverso, Carl M. Schoellhammer
Publikováno v:
Journal of Pharmaceutical Sciences. 111:1770-1775
The successful delivery of RNA therapeutics is the gating hurdle to greater clinical translation and utility of this novel class of therapeutics. Delivery strategies today are limited and predominantly rely on lipid nanoparticles or conjugates, which
Autor:
Marion M. France, Tony del Rio, Hannah Travers, Erin Raftery, Katherine Xu, Robert Langer, Giovanni Traverso, Jochen K. Lennerz, Carl M. Schoellhammer
Publikováno v:
Journal of Controlled Release. 304:1-6
The delivery of therapeutics to the gastrointestinal (GI) mucosa remains primarily a function of diffusion and rapid delivery is a significant goal in drug delivery science. However, delivery is hindered by the molecular barrier properties of the muc
Autor:
Esteban A. Engel, Jiun-Ruey Hu, Ian B. Hogue, Jens B. Bosse, Julian Scherer, Lynn W. Enquist, Tony Del Rio
Publikováno v:
Viruses
Viruses, Vol 7, Iss 11, Pp 5933-5961 (2015)
Viruses, Vol 7, Iss 11, Pp 5933-5961 (2015)
In the nearly two decades since the popularization of green fluorescent protein (GFP), fluorescent protein-based methodologies have revolutionized molecular and cell biology, allowing us to literally see biological processes as never before. Naturall
Autor:
Lisa V. Goodrich, Andrea R. Yung, Gary C. Schoenwolf, Donna M. Fekete, Tony del Rio, Allison M. Nishitani, Victoria E. Abraira, Sho Ohta, Michael I. Gordon, Evelyn C. Avilés
Publikováno v:
Development.
The vestibular system of the inner ear detects head position using three orthogonally oriented semicircular canals; even slight changes in their shape and orientation can cause debilitating behavioral defects. During development, the canals are sculp
Autor:
Hannah L. Keirnes, John Slonimsky, Victoria E. Abraira, Andrew F. Tucker, Tony del Rio, Lisa V. Goodrich
Publikováno v:
Development. 135:4091-4099
The sense of balance depends on the intricate architecture of the inner ear, which contains three semicircular canals used to detect motion of the head in space. Changes in the shape of even one canal cause drastic behavioral deficits, highlighting t
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 9, Iss 9, p e1003824 (2013)
PLoS Genetics, Vol 9, Iss 9, p e1003824 (2013)
Lrig proteins are conserved transmembrane proteins that modulate a variety of signaling pathways from worm to humans. In mammals, there are three family members – Lrig1, Lrig2, and Lrig3 – that are defined by closely related extracellular domains