Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Tony Z. Xiao"'
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23747 (2011)
Class I MAGE proteins (MAGE I) are normally expressed only in developing germ cells but are aberrantly expressed in many cancers. They have been shown to promote tumor survival, aggressive growth, and chemoresistance but the underlying mechanisms and
Externí odkaz:
https://doaj.org/article/a1c6190082264d30a557c0c5d7b55955
Expression of Melanoma AntiGen Encoding (MAGE) genes, particularly MAGE-A3, has been correlated with aggressive clinical course, the acquisition of resistance to chemotherapy and poor clinical outcomes of melanoma and other malignancies. MAGE protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b39bb76721d677ab8d7eaf540d32bc
https://europepmc.org/articles/PMC4221552/
https://europepmc.org/articles/PMC4221552/
Autor:
Imtiaz A. Siddiqui, Brendan Smart, Qiao Meng, Shannon C. Kenney, Hasan Mukhtar, Cindy L. Zuleger, Tony Z. Xiao, B. Jack Longley, Neehar Bhatia, Mark R. Albertini, Kimberly A. Rosenthal, Saravanan Thiyagarajan
Publikováno v:
The Journal of investigative dermatology. 133(3)
Melanoma-associated antigen-encoding (MAGE) genes are expressed in melanoma and other cancers but not in normal somatic cells. MAGE expression is associated with aggressive tumor growth, poor clinical outcome, and resistance to chemotherapy, but the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa5c436c9da166d74c784e9d141bf9a8
https://pubmed.ncbi.nlm.nih.gov/23096706
https://pubmed.ncbi.nlm.nih.gov/23096706
The Class I MAGE proteins are normally expressed only in developing germ cells but are often aberrantly expressed in malignancies, particularly melanoma, making them good therapeutic targets. MAGE proteins promote tumor survival by binding to the RBC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::533bbb80301265f1623ead049debb756
https://europepmc.org/articles/PMC3149886/
https://europepmc.org/articles/PMC3149886/
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23747 (2011)
PLoS ONE
PLoS ONE
Class I MAGE proteins (MAGE I) are normally expressed only in developing germ cells but are aberrantly expressed in many cancers. They have been shown to promote tumor survival, aggressive growth, and chemoresistance but the underlying mechanisms and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89432a56c48d9c9d92b6feb7b63302cb
https://doi.org/10.1371/journal.pone.0023747
https://doi.org/10.1371/journal.pone.0023747