Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Tony Y, Hu"'
Autor:
Zhen Huang, Lili Zhang, Christopher J. Lyon, Bo Ning, Brady M. Youngquist, Alex Niu, Brandon J. Beddingfield, Nicholas J. Maness, Nakhle S. Saba, Chen-Zhong Li, Chad J. Roy, Tony Y. Hu
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 629-638 (2022)
Mounting evidence indicates that SARS-CoV-2 can infect multiple systemic tissues, but few studies have evaluated SARS-CoV-2 RNA dynamics in multiple specimen types due to their reduced accessibility and diminished performance of RT-qPCR with non-resp
Externí odkaz:
https://doaj.org/article/37331d055e52443da112f8ee0fb7a565
Autor:
Xiaojun Wei, Xiaoqin Wang, Zehui Zhang, Yuanyuan Luo, Zixin Wang, Wen Xiong, Piyush K. Jain, John R. Monnier, Hui Wang, Tony Y. Hu, Chuanbing Tang, Helmut Albrecht, Chang Liu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Accurate detection of antigen p24 for HIV−1 early diagnosis remains challenging. Here the authors present a click chemistry amplified nanopore (CAN) assay that allows p24 quantification at ultralow concentration range in clinical samples.
Externí odkaz:
https://doaj.org/article/a53cd8defb0a4df3886cc8a157c25efb
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 10, Pp 3822-3842 (2022)
Extracellular vesicles (EVs) are secreted by both eukaryotes and prokaryotes, and are present in all biological fluids of vertebrates, where they transfer DNA, RNA, proteins, lipids, and metabolites from donor to recipient cells in cell-to-cell commu
Externí odkaz:
https://doaj.org/article/4c06499a000d45edbe1093df6bcf1ef0
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Tuberculosis (TB) remains a major underdiagnosed public health threat worldwide, being responsible for more than 10 million cases and one million deaths annually. TB diagnosis has become more rapid with the development and adoption of molecular tests
Externí odkaz:
https://doaj.org/article/62b9ebc22df244a89fa663b4de20b0c1
Autor:
Ibolya Rutkai, Meredith G. Mayer, Linh M. Hellmers, Bo Ning, Zhen Huang, Christopher J. Monjure, Carol Coyne, Rachel Silvestri, Nadia Golden, Krystle Hensley, Kristin Chandler, Gabrielle Lehmicke, Gregory J. Bix, Nicholas J. Maness, Kasi Russell-Lodrigue, Tony Y. Hu, Chad J. Roy, Robert V. Blair, Rudolf Bohm, Lara A. Doyle-Meyers, Jay Rappaport, Tracy Fischer
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
COVID-19 can result in neurological manifestations and animal models could provide insights into the mechanisms. Here, the authors describe neuroinflammation, microhemorrhages and brain hypoxia in SARS-CoV-2 infected non-human primates, including in
Externí odkaz:
https://doaj.org/article/0c1be27d8686492ebe212a4588149d65
Publikováno v:
Materials Today Bio, Vol 18, Iss , Pp 100538- (2023)
Exosomes are membrane-defined extracellular vesicles (EVs) approximately 40–160 nm in diameter that are found in all body fluids including blood, urine, and saliva. They act as important vehicles for intercellular communication between both loca
Externí odkaz:
https://doaj.org/article/49b7e1b6c0c448c2b2addb50a66d7f67
Publikováno v:
BME Frontiers, Vol 4 (2023)
Extensive effort has been devoted to the discovery, development, and validation of biomarkers for early disease diagnosis and prognosis as well as rapid evaluation of the response to therapeutic interventions. Genomic and transcriptomic profiling are
Externí odkaz:
https://doaj.org/article/6f4f541d7ecd4594bf0c7ea1b5705d9d
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1493-1512 (2021)
Macrophages are typically identified as classically activated (M1) macrophages and alternatively activated (M2) macrophages, which respectively exhibit pro- and anti-inflammatory phenotypes, and the balance between these two subtypes plays a critical
Externí odkaz:
https://doaj.org/article/bb5127c5325546ccbec51fcfba0227ce
Autor:
Liyan Mao, Sylvia M. LaCourse, Soyeon Kim, Chang Liu, Bo Ning, Duran Bao, Jia Fan, Christopher J. Lyon, Ziyong Sun, Sharon Nachman, Charles D. Mitchell, Tony Y. Hu
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-12 (2021)
Abstract Background Non-sputum methods are urgently needed to improve tuberculosis diagnosis and treatment monitoring in children. This study evaluated the ability of a serum assay quantifying a species-specific peptide of the Mycobacterium tuberculo
Externí odkaz:
https://doaj.org/article/11abb6089acd4ca0a241b4aa76960ff6
Autor:
Chen-zhong Li, Tony Y. Hu
Publikováno v:
Research, Vol 2022 (2022)
Externí odkaz:
https://doaj.org/article/7102bc04efd14ba5b85f38a014517a26