Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Tony Woolard"'
Autor:
Alison Morris, Panayiotis V. Benos, Ronald G. Collman, Kevin F. Gibson, Milica Vukmirovic, Yingze Zhang, Heather Lynn, Xiting Yan, Buqu Hu, David R. Moller, Joe G.N. Garcia, Michael J. Becich, Giuseppe DeIuliis, Jonas C. Schupp, Laura L. Koth, Joseph K. Leader, S. R. Wisniewski, Taylor Adams, Edward S. Chen, Mridu Gulati, Antje Prasse, Lisa A. Maier, Erica L. Herzog, Harry Hochheiser, Nkiruka Emeagwali, Naftali Kaminski, Tony Woolard, Wonder P. Drake, Antun Mihaljinec
Publikováno v:
Eur Respir J
Sarcoidosis is a multisystem granulomatous disease of unknown origin with a variable and often unpredictable course and pattern of organ involvement. In this study we sought to identify specific bronchoalveolar lavage (BAL) cell gene expression patte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7fbbfc654806b01b758a0cccc779525
https://europepmc.org/articles/PMC9759791/
https://europepmc.org/articles/PMC9759791/
Autor:
Mridu Gulati, Wajahat Z. Mehal, Jaden Faunce, Caitlin Brandsdorfer, Jose D. Herazo-Maya, Varvara Kirillov, Jonathan Puchalski, Daniel F Bogenhagen, Christina Blaul, Erica L. Herzog, Anjelica L. Gonzalez, Glenda Trujillo, Raimund I. Herzog, Kathleen O. Lindell, Martin D. Slade, Huanxing Sun, Changwan Ryu, Kevin F. Gibson, Naftali Kaminski, Yonglin Chen, Julia Winkler, Argyrios Tzouvelekis, Danielle Antin-Ozerkis, Tony Woolard, Hongyi Pan, Carol Feghali-Bostwick, Charles S. Dela Cruz, Awo Osafo-Addo
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 196:1571-1581
Idiopathic pulmonary fibrosis (IPF) involves the accumulation of α-smooth muscle actin-expressing myofibroblasts arising from interactions with soluble mediators such as transforming growth factor-β1 (TGF-β1) and mechanical influences such as loca
Autor:
Thomas S. Scanlan, Xinran Liu, Tony Woolard, Jose D. Herazo-Maya, Antonio C. Bianco, Robert J. Homer, Erica L. Herzog, Guoying Yu, Farida Ahangari, Nachelle Aurelien, Rong Wang, Naftali Kaminski, Morven Graham, Gabriel Ibarra, Rafael Arrojo e Drigo, Joao Pedro Werneck de Castro, Argyris Tzouvelekis, Anup Srivastava, Ye Gan, Giuseppe DeIuliis, Patty J. Lee, Praveen Mannam
Publikováno v:
Nature medicine
Thyroid hormone (TH) is critical for the maintenance of cellular homeostasis during stress responses, but its role in lung fibrosis is unknown. Here we found that the activity and expression of iodothyronine deiodinase 2 (DIO2), an enzyme that activa
Publikováno v:
European Journal of Pharmacology. 808:35-43
Pulmonary fibrosis (PF) constitutes the end stage of a broad range of heterogeneous interstitial lung diseases, characterized by the destruction of the pulmonary parenchyma, deposition of extracellular matrix and dramatic changes in the phenotype of
Autor:
Xiting Yan, Aurelie Fabre, Luca Richeldi, Mark Jones, G. Deluliis, Buqu Hu, J.H. Maya, Franco Conforti, Tony Woolard, Christopher J. Brereton, Aiman Alzetani, Naftali Kaminski, Antun Mihaljinec, David E. Smart, Benjamin Marshall, Milica Vukmirovic, Robert J. Homer, Nikos Xylourgidis, Donna E. Davies, Farida Ahangari
Publikováno v:
C59. GENETIC AND EPIGENETIC MECHANISMS IN PULMONARY FIBROSIS.
Autor:
Taylor Adams, Buqu Hu, Scott M. O'Neal, Tony Woolard, Panagiotis V. Benos, Michael J. Becich, Yingze Zhang, David R. Moller, Erica L. Herzog, Joseph K. Leader, Robert M. Senior, Mridu Gulati, Hubertus D. Luijk, Nachelle Aurelien, Laura L. Koth, Alison Morris, Harry Hochheiser, Xiting Yan, Naftali Kaminski, Stephen R. Wisniewski, Kevin F. Gibson, Wenlan Zang, Giuseppe DeIuliis, Joe G. N. Garcia, Antun Mihaljinec, Wonder P. Drake, Milica Vukmirovic, Lisa A. Maier, Edward S. Chen
Publikováno v:
Molecular Pathology and Functional Genomics.
Introduction: We analyzed the transcriptome of bronchoalveolar lavage cells (BAL) in a large cohort of well characterized sarcoidosis subjects by RNA-sequencing to better understand disease progression and severity, and potentially identify novel mol
Autor:
Jae Sung Yi, Hojin Lee, Argyrios Tzouvelekis, Jose D. Herazo-Maya, Rong Wang, Nikolaos Xylourgidis, Yi Zhang, Patty J. Lee, Tony Woolard, Vassilis Aidinis, Robert J. Homer, Guoying Yu, Naftali Kaminski, Erica L. Herzog, Christian L. Lino Cardenas, Farida Ahangari, Koji Sakamoto, Anton M. Bennett, Giuseppe DeIuliis
Publikováno v:
American Journal of Respiratory and Critical Care Medicine
Idiopathic pulmonary fibrosis (IPF) is a chronic fatal lung disease with dismal prognosis and no cure. The potential role of the ubiquitously expressed SH2 domain-containing tyrosine phosphatase-2 (SHP2) as a therapeutic target has not been studied i
Autor:
Min Kisuk, Guoying Yu, Argyrios Tzouvelekis, Nikos Xylourgidis, Leonhard Binzenhöfer, Naftali Kaminski, Gabriel Ibarra, Jose D. Herazo-Maya, Anton M. Bennett, Giuseppe DeIuliis, Taylor Adams, Nachelle Aurelien, Tony Woolard
Publikováno v:
QJM: An International Journal of Medicine.
Autor:
Jose D. Herazo-Maya, Patty J. Lee, Hojin Lee, Anton M. Bennett, Argyris Tzouvelekis, Erica L. Herzog, Yi Zhang, Tony Woolard, Guoying Yu, Naftali Kaminski
Publikováno v:
3.2 Airway Cell Biology and Immunopathology.
Rationale: Idiopathic Pulmonary Fibrosis (IPF) is a chronic fatal lung disease with dismal prognosis and ineffective treatment. The potential role of the ubiquitously expressed SH2 domain-containing-tyrosine phosphatase (SHP2) as a therapeutic target
Autor:
Erica L. Herzog, Tony Woolard, Patty J. Lee, Antonio C. Bianco, Guoying Yu, Naftali Kaminski, Jose D. Herazo-Maya, Rong Wang, Argyris Tzouvelekis, Anup Srivastava, Rafael Arrojo e Drigo, Robert J. Homer, Joao Pedro Werneck de Castro, Giuseppe DeIuliis, Farida Ahangari
Publikováno v:
1.5 Diffuse Parenchymal Lung Disease.
Background: Thyroid hormone (TH) is critical for maintenance of mitochondrial homeostasis during stress responses, but its role in lung fibrosis is unknown. Methods and Results: Microarray data analysis revealed that DIO2 was significantly increased