Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Tony W. Ng"'
Autor:
Tony W. Ng, Wakako Furuyama, Ariel S. Wirchnianski, Noemí A. Saavedra-Ávila, Christopher T. Johndrow, Kartik Chandran, William R. Jacobs, Andrea Marzi, Steven A. Porcelli
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Previous studies have demonstrated the efficacy and feasibility of an anti-viral vaccine strategy that takes advantage of pre-existing CD4+ helper T (Th) cells induced by Mycobacterium bovis bacille Calmette-Guérin (BCG) vaccination. This strategy u
Externí odkaz:
https://doaj.org/article/f8873c18c52a478ba7ece8617e9ee5b6
Autor:
Shivani Singh, David Kanzin, Sarah Chavez, Noemi Alejandra Saavedra-Avila, Tony W. Ng, Regy Lukose, Oren Mayer, John Kim, Bing Chen, Mei Chen, Steven A. Porcelli, William R. Jacobs, Sangeeta Tiwari
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1571 (2024)
Tuberculosis (TB) continues to be a major global health burden and kills over a million people annually. New immunization strategies are required for the development of an efficacious TB vaccine that can potentially induce sterilizing immunity. In th
Externí odkaz:
https://doaj.org/article/29883398ba6c467bb279faa3db5abe23
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Autophagy is an ubiquitous homeostatic pathway in mammalian cells and plays a significant role in host immunity. Substantial evidence indicates that the ability of Mycobacterium tuberculosis (Mtb) to successfully evade immune responses is pa
Externí odkaz:
https://doaj.org/article/16228802e57646cea85b5b21245b9565
Publikováno v:
mSphere, Vol 6, Iss 4 (2021)
Tuberculosis is a significant global infectious disease caused by infection of the lungs with Mycobacterium tuberculosis
Externí odkaz:
https://doaj.org/article/1ef47d2962b04474b01ebde0a91eb440
Autor:
Ariel S. Wirchnianski, Anna Z. Wec, Tony W. Ng, Steven A. Porcelli, Kartik Chandran, Hua-Xin Liao, J. Maximilian Fels, Christopher T. Johndrow, Kevin O. Saunders, John Chan, William R. Jacobs
Publikováno v:
The Journal of Immunology. 205:425-437
The continuing emergence of viral pathogens and their rapid spread into heavily populated areas around the world underscore the urgency for development of highly effective vaccines to generate protective antiviral Ab responses. Many established and n
Publikováno v:
mSphere
mSphere, Vol 6, Iss 4 (2021)
mSphere, Vol 6, Iss 4 (2021)
Autophagy is a fundamental cellular process that has important roles in innate and adaptive immunity against a broad range of microbes. Many pathogenic microbes have evolved mechanisms to evade or exploit autophagy. It has been previously demonstrate
Autor:
Grégoire Lauvau, John Chan, Nazanin Khajoueinejad, Christopher T. Johndrow, Michael F. Goldberg, William R. Jacobs, Noemi Alejandra Saavedra-Avila, Steven A. Porcelli, Jiayong Xu, Betsy C. Herold, Tony W. Ng, Alison J. Johnson, Shajo Kunnath-Velayudhan, John Kim, Pooja Arora, Christopher Petro, Neeraj K. Saini
Publikováno v:
ImmunoHorizons. 3:161-171
During Ag priming, naive CD4+ T cells differentiate into subsets with distinct patterns of cytokine expression that dictate to a major extent their functional roles in immune responses. We identified a subset of CD4+ T cells defined by secretion of I
Autor:
Manjunatha M Venkataswamy, Tony W Ng, Shalu S Kharkwal, Leandro J Carreño, Alison J Johnson, Shajo Kunnath-Velayudhan, Zheng Liu, Robert Bittman, Peter J Jervis, Liam R Cox, Gurdyal S Besra, Xiangshu Wen, Weiming Yuan, Moriya Tsuji, Xiangming Li, David D Ho, John Chan, Sunhee Lee, Richard Frothingham, Barton F Haynes, Michael W Panas, Geoffrey O Gillard, Jaimie D Sixsmith, Birgit Korioth-Schmitz, Joern E Schmitz, Michelle H Larsen, William R Jacobs, Steven A Porcelli
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108383 (2014)
Recombinant Mycobacterium bovis bacillus Calmette-Guèrin (rBCG) has been explored as a vector for vaccines against HIV because of its ability to induce long lasting humoral and cell mediated immune responses. To maximize the potential for rBCG vacci
Externí odkaz:
https://doaj.org/article/90e45a31ded54c5cbca2c3231d0f0e54
Autor:
Ulrich D. Kadolsky, Daniel H. Kaplan, Alison J. Johnson, Tony W. Ng, Andrew J. Yates, Steven A. Porcelli, Grégoire Lauvau, Shajo Kunnath-Velayudhan, G. H. Gossel, William R. Jacobs, John Chan, Christopher T. Johndrow, Michael F. Goldberg
Publikováno v:
The Journal of Immunology. 201:3604-3616
Effective subunit vaccines require the incorporation of adjuvants that stimulate cells of the innate immune system to generate protective adaptive immune responses. Pattern recognition receptor agonists are a growing class of potential adjuvants that
Autor:
Betsy C. Herold, Jiayong Xu, Steven A. Porcelli, Neeraj K. Saini, Tony W. Ng, Shajo Kunnath-Velayudhan, William R. Jacobs, Michael F. Goldberg, John Chan, John Kim, Pooja Arora
Interleukin-3 (IL-3) is produced during infections caused by parasites, bacteria and viruses, but its contribution to immunity in this context remains largely unknown. In mouse models of parasitic infections, in which the effects of IL-3 have been mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7774d91d32143be16a8d2e27fa2e2bc
https://doi.org/10.1101/2021.03.07.434271
https://doi.org/10.1101/2021.03.07.434271