Preserved regulation of renal perfusion pressure by small and intermediate conductance KCa channels in hypertensive mice with or without renal failure

Autor: Ralf Köhler, Ludovic Waeckel, Michel Félétou, Heike Wulff, Nicolas Clavreul, Tony Verbeuren, Thibaut Damery, Serge Simonet, Florence Bertin, Jerome Paysant, Christine Vayssettes-Courchay, Patricia Sansilvestri-Morel

Publikováno v: Waeckel, L, Bertin, F, Clavreul, N, Damery, T, Köhler, R, Paysant, J, Sansilvestri-Morel, P, Simonet, S, Vayssettes-Courchay, C, Wulff, H, Verbeuren, T J & Feletou, M 2015, ' Preserved regulation of renal perfusion pressure by small and intermediate conductance K-Ca channels in hypertensive mice with or without renal failure ', Pflügers Archiv-European Journal of Physiology, vol. 467, no. 4, pp. 817-831 . https://doi.org/10.1007/s00424-014-1542-y
Pflugers Archiv : European journal of physiology, vol 467, iss 4

The purpose of this study was to assess, in the murine kidney, the mechanisms underlying the endothelium-dependent control of vascular tone and whether or not, in a severe model of hypertension and renal failure, K-Ca channels contribute to its regul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20f1f79e7f431d151cd333e3d822c0cb
https://doi.org/10.1007/s00424-014-1542-y

Activation of thromboxane receptor modulates interleukin-1β-induced monocyte adhesion―A novel role of Nox1

Autor: Bingbing Jiang, David R. Pimentel, Ralf P. Brandes, Hossein Bayat, Richard A. Cohen, Katrin Schröder, Tony Verbeuren

Publikováno v: Free Radical Biology and Medicine. 52:1760-1766

Activation of thromboxane receptors (TPr) may promote atherosclerosis by enhancing oxidative stress and the inflammation. This study examined the role of Nox1, an NADPH-oxidase subunit, in the enhancement of interleukin (IL)-1β-induced monocyte adhe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b19d4ec84e46712fcde005264d8a3f2a
https://doi.org/10.1016/j.freeradbiomed.2012.02.052

(Pro)renin promotes fibrosis gene expression in HEK cells through a Nox4-dependent mechanism

Autor: Delphine Magard, Alain Rupin, Tony Verbeuren, Patricia Sansilvestri-Morel, Nicolas Clavreul

Publikováno v: American Journal of Physiology-Renal Physiology. 300:F1310-F1318

The (pro)renin receptor (PRR) has recently been demonstrated to bind equally well renin and its precursor, prorenin, leading to a similar intracellular signaling independent of angiotensin II. In this study, we report that human embryonic kidney cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9cfa335e2e4e262a0fe75097bbce5bf
https://doi.org/10.1152/ajprenal.00119.2010

The anti-aggregating effect of BAY 41-2272, a stimulator of soluble guanylyl cyclase, requires the presence of nitric oxide

Autor: Michel Félétou, Séverine Roger, Alex Cordi, Cécile Badier-Commander, Tony Verbeuren, Jerome Paysant

Publikováno v: British Journal of Pharmacology. 161:1044-1058

BACKGROUND AND PURPOSE The purpose of the present study was to determine whether a stimulator of soluble guanylyl cyclase, BAY 41-2272, inhibits platelet aggregation and to clarify its interaction with nitric oxide (NO). EXPERIMENTAL APPROACH Blood w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f6a358ae975d9aaf54de64ebbe4bf03d
https://doi.org/10.1111/j.1476-5381.2010.00943.x

In vitro and in vivo studies of 6,8-(diaryl)imidazo[1,2-a]pyrazin-3(7H)-ones as new antioxidants

Autor: Paul Jeanjot, Tony Verbeuren, Cédric Moens, Jean-François Rees, Alex Cordi, Eliete Bouskela, Jacqueline Marchand-Brynaert, Frederic De Wael

Publikováno v: Bioorganic & Medicinal Chemistry. 17:4336-4344

A series of 5-aryl and 3,5-diaryl-2-amino-1,4-pyrazines and the derived imidazopyrazinones has been synthesized to study the chemical oxidative degradation of the bicyclic systems in vitro. Imidazopyrazinones mainly degraded following two independent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb9f42727a1450115c5806993ab95ca3
https://doi.org/10.1016/j.bmc.2009.05.025