CD200 is up-regulated in R6/1 transgenic mouse model of Huntington's disease.

Autor: Andrea Comella Bolla, Tony Valente, Andres Miguez, Veronica Brito, Silvia Gines, Carme Solà, Marco Straccia, Josep M Canals

Publikováno v: PLoS ONE, Vol 14, Iss 12, p e0224901 (2019)

In Huntington's disease (HD), striatal medium spiny neurons (MSNs) are particularly sensitive to the presence of a CAG repeat in the huntingtin (HTT) gene. However, there are many evidences that cells from the peripheral immune system and central ner

Externí odkaz: https://doaj.org/article/8a2fc1e286e7464291471f42703ea303

Alterations in CD200-CD200R1 System during EAE Already Manifest at Presymptomatic Stages

Autor: Tony Valente, Joan Serratosa, Unai Perpiñá, Josep Saura, Carme Solà

Publikováno v: Frontiers in Cellular Neuroscience, Vol 11 (2017)

In the brain of patients with multiple sclerosis, activated microglia/macrophages appear in active lesions and in normal appearing white matter. However, whether they play a beneficial or a detrimental role in the development of the pathology remains

Externí odkaz: https://doaj.org/article/021ebbf5b97a42cb90d1d80148183389

Passive experimental autoimmune encephalomyelitis in C57BL/6 with MOG: evidence of involvement of B cells.

Autor: Francesco Mannara, Tony Valente, Josep Saura, Francesc Graus, Albert Saiz, Beatriz Moreno

Publikováno v: PLoS ONE, Vol 7, Iss 12, p e52361 (2012)

Experimental autoimmune encephalomyelitis (EAE) is the most relevant animal model to study demyelinating diseases such as multiple sclerosis. EAE can be induced by active (active EAE) or passive (at-EAE) transfer of activated T cells in several speci

Externí odkaz: https://doaj.org/article/f5d1d00861a74c9082d8ef444d93af75

From Mouse To Human : Comparative Analysis Between Grey And White Matter By Synchrotron-Fourier Transformed Infrared Microspectroscopy

Autor: Martin Kreuzer, Alex Perálvarez-Marín, Beatriz Almolda, Núria Benseny-Cases, Paula Sanchez-Molina, Tony Valente, Berta González, Bernardo Castellano

Publikováno v: Biomolecules
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Biomolecules, Vol 10, Iss 1099, p 1099 (2020)

Fourier Transform Infrared microspectroscopy (μFTIR) is a very useful method to analyze the biochemical properties of biological samples in situ. Many diseases affecting the central nervous system (CNS) have been studied using this method, to elucid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8d6586bf6772d9adaf351e88cf1e6f9
https://ddd.uab.cat/record/233219

Alterations in CD200-CD200R1 System during EAE Already Manifest at Presymptomatic Stages

Autor: Unai Perpiñá, Joan Serratosa, Carme Solà, Tony Valente, Josep Saura

Publikováno v: Frontiers in Cellular Neuroscience
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Digital.CSIC. Repositorio Institucional del CSIC

In the brain of patients with multiple sclerosis, activated microglia/macrophages appear in active lesions and in normal appearing white matter. However, whether they play a beneficial or a detrimental role in the development of the pathology remains

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf8131afd94348e616db04d2a00cf527
http://hdl.handle.net/10261/153080