Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Tony S Cardno"'
Autor:
Suneeth F Mathew, Caillan Crowe-McAuliffe, Ryan Graves, Tony S Cardno, Cushla McKinney, Elizabeth S Poole, Warren P Tate
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122176 (2015)
HIV-1 utilises -1 programmed ribosomal frameshifting to translate structural and enzymatic domains in a defined proportion required for replication. A slippery sequence, U UUU UUA, and a stem-loop are well-defined RNA features modulating -1 frameshif
Externí odkaz:
https://doaj.org/article/87d15fa289194209897c68af85fac57f
Autor:
Tony S Cardno, Yosuke Shimaki, Brad E Sleebs, Kurt Lackovic, John P Parisot, Rebecca M Moss, Caillan Crowe-McAuliffe, Suneeth F Mathew, Christina D Edgar, Torsten Kleffmann, Warren P Tate
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139036 (2015)
Frameshifting during translation of viral or in rare cases cellular mRNA results in the synthesis of proteins from two overlapping reading frames within the same mRNA. In HIV-1 the protease, reverse transcriptase, and integrase enzymes are in a secon
Externí odkaz:
https://doaj.org/article/20a5de53f7ec45b591411810ac7d69b1
Autor:
Irena Ivnitski-Steele, Brian C. Monk, Kurt Lackovic, Richard D. Cannon, J. Jacob Strouse, Mikhail V. Keniya, Larry A. Sklar, Tony S. Cardno, Ann R. Holmes
Publikováno v:
Future Medicinal Chemistry. 8:1485-1501
Resistance to antifungal drugs is an increasingly significant clinical problem. The most common antifungal resistance encountered is efflux pump-mediated resistance of Candida species to azole drugs. One approach to overcome this resistance is to inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6079c96ff16c2c44a2aa494a32a89687
https://doi.org/10.4155/fmc-2016-0050
https://doi.org/10.4155/fmc-2016-0050
Autor:
Baerbel Ruttkowski, Anja Joachim, Abdul Jabbar, Sarah Preston, Tony S. Cardno, Andreas Hofmann, Robin B. Gasser, Cameron J. Nowell
Publikováno v:
Molecular and Cellular Probes. 30:13-17
Here, we provide a step-by-step protocol for a practical and low cost whole-organism assay for the screening of chemical compounds for activity against parasitic worms. This assay has considerable advantages over conventional methods, mainly in relat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6403544adfb3df1f71b3287e49efab28
https://doi.org/10.1016/j.mcp.2015.08.005
https://doi.org/10.1016/j.mcp.2015.08.005
Autor:
Jonathan B. Baell, Andreas Hofmann, David Piedrafita, Sarah Preston, Tony S. Cardno, Brendan R E Ansell, Cameron J. Nowell, Aaron R. Jex, Bärbel Ruttkowski, Abdul Jabbar, Anja Joachim, Robin B. Gasser, Pasi K. Korhonen
Publikováno v:
International Journal for Parasitology. 45:333-343
Due to major problems with drug resistance in parasitic nematodes of animals, there is a substantial need and excellent opportunities to develop new anthelmintics via genomic-guided and/or repurposing approaches. In the present study, we established
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ec36646ab8143a2de518b40d6a6addd
https://doi.org/10.1016/j.ijpara.2015.01.007
https://doi.org/10.1016/j.ijpara.2015.01.007
Autor:
Warren P. Tate, John P Parisot, Rebecca M Moss, Suneeth F. Mathew, Torsten Kleffmann, Tony S. Cardno, Brad E. Sleebs, Yosuke Shimaki, Caillan Crowe-McAuliffe, Kurt Lackovic, Christina D. Edgar
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 10, p e0139036 (2015)
PLoS ONE, Vol 10, Iss 10, p e0139036 (2015)
Frameshifting during translation of viral or in rare cases cellular mRNA results in the synthesis of proteins from two overlapping reading frames within the same mRNA. In HIV-1 the protease, reverse transcriptase, and integrase enzymes are in a secon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1307c68b2ad27c614da560754eed9eb
https://pubmed.ncbi.nlm.nih.gov/26447468
https://pubmed.ncbi.nlm.nih.gov/26447468
Autor:
Sarah Goddard, Neil V. Morgan, Warren P. Tate, Fatimah Rahman, David McDonald, Andrew Ciupek, Graham Anderson, Mary Guckian, Dawn Barge, Eamonn R. Maher, Aarnoud Huissoon, Tony S. Cardno, Andrew J. Cant, Shanaz Pasha, Sophie Hambleton, Anna Straatman-Iwanowska
Inherited immunodeficiency disorders can be caused by mutations in any one of a large number of genes involved in the function of immune cells. Here, we describe two families with an autosomal recessive inherited immunodeficiency disorder characteriz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93461906982fdd9c706fb509c8f4db7c
https://europepmc.org/articles/PMC3026716/
https://europepmc.org/articles/PMC3026716/
Publikováno v:
RNA
Recoding mechanisms are programmed protein synthesis events used commonly by viruses but only very rarely in cells for cellular gene expression. For example, HIV-1 has an absolute reliance on frameshifting to produce the correct ratio of key proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd897d9eaf45078084e68c0f263ce60
https://europepmc.org/articles/PMC2714747/
https://europepmc.org/articles/PMC2714747/
Autor:
Warren P. Tate, Elizabeth S. Poole, Cushla McKinney, Ryan Graves, Suneeth F. Mathew, Tony S. Cardno, Caillan Crowe-McAuliffe
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122176 (2015)
PLoS ONE
PLOS ONE
PLoS ONE
PLOS ONE
HIV-1 utilises −1 programmed ribosomal frameshifting to translate structural and enzymatic domains in a defined proportion required for replication. A slippery sequence, U UUU UUA, and a stem-loop are well-defined RNA features modulating −1 frame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80376daa9a412b796b628573f28987a0
https://doi.org/10.1371/journal.pone.0122176
https://doi.org/10.1371/journal.pone.0122176