Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tony R. Fox"'
Publikováno v:
Carcinogenicity ISBN: 9781003067641
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4de54b7f17bafb1aeb3cb4cc62bb402d
https://doi.org/10.1201/9781003067641-5
https://doi.org/10.1201/9781003067641-5
Publikováno v:
Molecular Carcinogenesis. 40:62-72
The present work describes the use of the infant (4-wk-old) mouse as an animal model for the study of DNA damage–induced G1 checkpoint response, changes in p53 protein levels, and multiple gene expression changes after DNA damage has been induced i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::684dc33778ac0e4981a63e28fdc75827
https://doi.org/10.1002/mc.20017
https://doi.org/10.1002/mc.20017
Publikováno v:
Physiological Genomics. 8:115-122
Expression levels of 767 genes were measured in HepG2 cells at eight time points (0, 0.5, 1, 6, 12, 16, 20, and 24 h) following exposure to the oxidizing agent, diethyl maleate (DEM). DEM treatment caused an immediate and sustained loss of intracellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c400ef4bdfeccfad7c527f929f4a4c4
https://doi.org/10.1152/physiolgenomics.00064.2001
https://doi.org/10.1152/physiolgenomics.00064.2001
Autor:
David E. Malarkey, J C Corton, Tony R. Fox, L N Healy, J G Christensen, Elizabeth H. Romach, Steven P. Anderson, Russell C. Cattley, A J Gonzales, Thomas L. Goldsworthy
Publikováno v:
Carcinogenesis. 20:1583-1590
Dysregulation of apoptosis is an important component of multistage hepatocarcinogenesis. Members of the bcl-2 protein family are important in the regulation of apoptosis and their expression is altered in several cancers. The objectives of the presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc0d668707257758be2132e2d8d50765
https://doi.org/10.1093/carcin/20.8.1583
https://doi.org/10.1093/carcin/20.8.1583
Autor:
Tony R. Fox, J G Christensen, R J Preston, Andrea J. Gonzales, Thomas L. Goldsworthy, Thea D. Tlsty
Publikováno v:
Carcinogenesis. 19:1173-1183
Non-genotoxic chemical carcinogens are capable of inducing tumors in rodents without interacting with or directly altering the genetic material. Since a preponderance of evidence suggests that cancer results from the accumulation of genetic alteratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfdf16dfbe603056229abe26c1682e9a
https://doi.org/10.1093/carcin/19.7.1173
https://doi.org/10.1093/carcin/19.7.1173
Publikováno v:
Carcinogenesis. 19:1093-1102
Dysregulated cell proliferation is one phenotypic change associated with neoplasia. Key protein complexes involved in regulating cell division are composed of cyclins, cyclindependent kinases (CDK) and CDK inhibitors (CDI). Many virally transformed c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b46919e1e3ac2c39e579daa81a39d461
https://doi.org/10.1093/carcin/19.6.1093
https://doi.org/10.1093/carcin/19.6.1093
Autor:
Ronny Fransson-Steen, Tony R. Fox, Patricia M. Fernandez, Linda J. Pluta, Thomas L. Goldsworthy
Publikováno v:
Molecular Carcinogenesis. 20:317-326
Quantitative differences in the expression of oncogenes are a critical feature of the cancer process. Several methods are currently available for assessing differential gene expression, but none can be used to determine quantitative changes in gene e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f638a5285825b4f991acb5046f2fff0
https://doi.org/10.1002/(sici)1098-2744(199711)20:3<317::aid-mc8>3.0.co
https://doi.org/10.1002/(sici)1098-2744(199711)20:3<317::aid-mc8>3.0.co
Publikováno v:
Molecular Carcinogenesis. 19:31-38
In this study, we analyzed spontaneous hepatocellular carcinomas (HCCs) from male B6C3F1 mice for alterations in the expression of the genes for c-myc, insulin-like growth factor II (IGF-II), cyclin D1, transforming growth factor-alpha (TGF-alpha), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41ee41a70341de4e48a7b36b63724db0
https://doi.org/10.1002/(sici)1098-2744(199705)19:1<31::aid-mc5>3.0.co
https://doi.org/10.1002/(sici)1098-2744(199705)19:1<31::aid-mc5>3.0.co
Publikováno v:
Toxicology. 101:125-156
The mouse liver is a frequent target organ for chemical carcinogenesis (Huff et al., 1988, 1991; Gold et al., 1989) and tumor development exhibits preferential strain sensitivity (Dragani et al., 1992; Drinkwater and Bennett, 1991). In some reports a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1229e0238c0b6ef6a36d4df1038c8167
https://doi.org/10.1016/0300-483x(95)03112-s
https://doi.org/10.1016/0300-483x(95)03112-s
Publikováno v:
Fundamental and Applied Toxicology. 17:651-665
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a17c950cfc7a969ca7fb6df601367626
https://doi.org/10.1016/0272-0590(91)90175-4
https://doi.org/10.1016/0272-0590(91)90175-4