Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Tony R, Larson"'
Autor:
Theresa Catania, Yi Li, Thilo Winzer, David Harvey, Fergus Meade, Anna Caridi, Andrew Leech, Tony R. Larson, Zemin Ning, Jiyang Chang, Yves Van de Peer, Ian A. Graham
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
The STORR gene fusion event is a key step in the evolution of benzylisoquinoline alkaloid metabolism in opium poppy. Here, the authors combine phylogenetic, transcriptomic, metabolomic, biochemical and genomic analyses to show the STORR gene fusion o
Externí odkaz:
https://doaj.org/article/6889dc279a65464c809ea2d9d7653ccc
Autor:
Tomasz Czechowski, Caroline Branigan, Anne Rae, Deborah Rathbone, Tony R. Larson, David Harvey, Theresa M. Catania, Dong Zhang, Yi Li, Melissa Salmon, Dianna J. Bowles, Paul O´Maille, Ian A. Graham
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
The monoterpene camphor is produced in glandular secretory trichomes of the medicinal plant Artemisia annua, which also produces the antimalarial drug artemisinin. We have found that, depending on growth conditions, camphor can accumulate at levels r
Externí odkaz:
https://doaj.org/article/d02f492700174e0c8b0716edb1a10233
Autor:
Vijayendran Raghavendran, Joseph P. Webb, Michaël L. Cartron, Vicki Springthorpe, Tony R. Larson, Michael Hines, Hamza Mohammed, William B. Zimmerman, Robert K. Poole, Jeffrey Green
Publikováno v:
Biotechnology for Biofuels, Vol 13, Iss 1, Pp 1-16 (2020)
Abstract Background Industrial biotechnology will play an increasing role in creating a more sustainable global economy. For conventional aerobic bioprocesses supplying O2 can account for 15% of total production costs. Microbubbles (MBs) are micron-s
Externí odkaz:
https://doaj.org/article/8182eec9d439469a86486cb382205785
Publikováno v:
Frontiers in Plant Science, Vol 12 (2021)
Diterpene biosynthesis commonly originates with the methylerythritol phosphate (MEP) pathway in chloroplasts, leading to the C20 substrate, geranylgeranyl pyrophosphate (GGPP). The previous work demonstrated that over-expression of genes responsible
Externí odkaz:
https://doaj.org/article/a25aedfb058749699de99418fd606d6b
Autor:
Theresa Catania, Yi Li, Thilo Winzer, David Harvey, Fergus Meade, Anna Caridi, Andrew Leech, Tony R. Larson, Zemin Ning, Jiyang Chang, Yves Van de Peer, Ian A. Graham
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/2a3d0d24ab584178959954dc431c95aa
Autor:
Tomasz Czechowski, Mauro A. Rinaldi, Mufuliat Toyin Famodimu, Maria Van Veelen, Tony R. Larson, Thilo Winzer, Deborah A. Rathbone, David Harvey, Paul Horrocks, Ian A. Graham
Publikováno v:
Frontiers in Plant Science, Vol 10 (2019)
Artemisinin, a sesquiterpene lactone produced by Artemisia annua glandular secretory trichomes, is the active ingredient in the most effective treatment for uncomplicated malaria caused by Plasmodium falciparum parasites. Other metabolites in A. annu
Externí odkaz:
https://doaj.org/article/491276367ebd47e4840f54c07784d3c9
Autor:
Theresa M. Catania, Caroline A. Branigan, Natalia Stawniak, Jennifer Hodson, David Harvey, Tony R. Larson, Tomasz Czechowski, Ian A. Graham
Publikováno v:
Frontiers in Plant Science, Vol 9 (2018)
Artemisia annua is established as an efficient crop for the production of the anti-malarial compound artemisinin, a sesquiterpene lactone synthesized and stored in Glandular Secretory Trichomes (GSTs) located on the leaves and inflorescences. Amorpha
Externí odkaz:
https://doaj.org/article/9a55d6f3f5034409be586dcad021a9a0
Detailed Phytochemical Analysis of High- and Low Artemisinin-Producing Chemotypes of Artemisia annua
Autor:
Tomasz Czechowski, Tony R. Larson, Theresa M. Catania, David Harvey, Cenxi Wei, Michel Essome, Geoffrey D. Brown, Ian A. Graham
Publikováno v:
Frontiers in Plant Science, Vol 9 (2018)
Chemical derivatives of artemisinin, a sesquiterpene lactone produced by Artemisia annua, are the active ingredient in the most effective treatment for malaria. Comprehensive phytochemical analysis of two contrasting chemotypes of A. annua resulted i
Externí odkaz:
https://doaj.org/article/d8d0d194a9864cd1b688d1319eac40e0
Autor:
Andrew S. Mason, Claire L. Varley, Olivia M. Foody, Xiang Li, Katie Skinner, Dawn Walker, Tony R. Larson, Daisuke Wakamatsu, Simon C. Baker, Jennifer Southgate
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11871
Urothelium is a transitional, stratified epithelium that lines the lower urinary tract, providing a tight barrier to urine whilst retaining the capacity to stretch and rapidly resolve damage. The role of glycerophospholipids in urothelial barrier fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6f00fabfd1794adba0d44b1669d3b8
Autor:
Tomasz, Czechowski, Edith, Forestier, Sandesh H, Swamidatta, Alison D, Gilday, Amy, Cording, Tony R, Larson, David, Harvey, Yi, Li, Zhesi, He, Andrew J, King, Geoffrey D, Brown, Ian A, Graham
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(21)
Most macro- and polycyclic Euphorbiaceae diterpenoids derive from the common C20 precursor casbene. While the biosynthetic pathway from casbene to the lathyrane jolkinol C is characterized, pathways to other more complex classes of bioactive diterpen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::280e21dda278ea3008dc9515a112779f
https://pubmed.ncbi.nlm.nih.gov/35584121
https://pubmed.ncbi.nlm.nih.gov/35584121