Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Tony Purchio"'
Autor:
Ed Lim, Tony Purchio, Anne C Clermont, John J. Hunter, Scott K. Lyons, Joan Dusich, Kenneth D. Campbell, Darlene Jenkins, Lingyun Zhu, Richard Coffee, David S. Grass
Publikováno v:
Cancer Research. 66:4701-4707
Several transgenic mouse models of prostate cancer have been developed recently that are able to recapitulate many key biological features of the human condition. It would, therefore, be desirable to employ these models to test the efficacy of new th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcd531a05bd53c32132cdaae478e8002
https://doi.org/10.1158/0008-5472.can-05-3598
https://doi.org/10.1158/0008-5472.can-05-3598
Autor:
Kevin P. Francis, Jun Yu, Pamela R. Contag, Jagath L. Kadurugamuwa, Tony Purchio, Kshitij Modi
Publikováno v:
Infection and Immunity. 73:3878-3887
Urinary tract infections (UTIs) are among the most common bacterial infections acquired by humans, particularly in catheterized patients. A major problem with catheterization is the formation of bacterial biofilms on catheter material and the risk of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9cbac525d138aecaeb98194cc799ab0
https://doi.org/10.1128/iai.73.7.3878-3887.2005
https://doi.org/10.1128/iai.73.7.3878-3887.2005
Publikováno v:
Journal of Antimicrobial Chemotherapy. 55:528-534
Objectives To investigate in vivo fitness of rifampicin-resistant Staphylococcus aureus mutants in a mouse biofilm model using bioluminescence imaging. Materials and methods S. aureus was engineered with a luciferase operon to emit bioluminescence th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d57c9798a8b96e7b50fb21bf361e5f
https://doi.org/10.1093/jac/dki053
https://doi.org/10.1093/jac/dki053
Autor:
Kevin P. Francis, Carolyn Bellinger-Kawahara, Pamela R. Contag, Matthew J. Hawkinson, Danny Joh, Tony Purchio
Publikováno v:
Infection and Immunity. 68:3594-3600
Strains of Staphylococcus aureus were transformed with plasmid DNA containing a Photorhabdus luminescens lux operon ( luxABCDE ) that was genetically modified to be functional in both gram-positive and gram-negative bacteria. S. aureus cells containi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23424efd30dab6c749f6cb7212e7c18e
https://doi.org/10.1128/iai.68.6.3594-3600.2000
https://doi.org/10.1128/iai.68.6.3594-3600.2000
Autor:
Steven G. Smith, Kshitij Modi, Olivier Coquoz, Jagath L. Kadurugamuwa, Pamela R. Contag, Tony Purchio, Brad Rice
Publikováno v:
Infection and immunity. 73(12)
We developed a method for simultaneous in vivo biophotonic monitoring of pneumococcal meningitis and the accompanying neuronal injury in live transgenic mice. Streptococcus pneumoniae engineered for bioluminescence ( lux ) was used for direct visuali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07caf0e0f8ef2d383eedb811ea746819
https://pubmed.ncbi.nlm.nih.gov/16299273
https://pubmed.ncbi.nlm.nih.gov/16299273
Publikováno v:
Breast Cancer Research
Introduction Our goal was to generate xenograft mouse models of human breast cancer based on luciferase-expressing MDA-MB-231 tumor cells that would provide rapid mammary tumor growth; produce metastasis to clinically relevant tissues such as lymph n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6b3de22fda9d80babd3a355e10d1fba
https://doi.org/10.1186/bcr1026
https://doi.org/10.1186/bcr1026
Eradication of Staphylococcus aureus biofilms after rifampin treatment was tested in a mouse model of device-related infection by using biophotonic imaging. Following treatment, the bioluminescent signals decreased to undetectable levels, irrespectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::768371e2915b064ad3be19ae68c2a066
https://europepmc.org/articles/PMC415634/
https://europepmc.org/articles/PMC415634/
Autor:
Caroline D Scatena, Pamela R. Contag, Joan Dusich, Mischa A Hepner, Tony Purchio, Shang-Fan Yu, Darlene E. Jenkins, Yoko Oei
Publikováno v:
The Prostate. 59(3)
BACKGROUND Animal experiments examining hormone-sensitive metastatic prostate cancer using the human LNCaP cell line have been limited to endpoint analyses. To permit longitudinal studies, we generated a luciferase-expressing cell line and used biolu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b3bedf8e54d1eca2087fa09003c68ab
https://pubmed.ncbi.nlm.nih.gov/15042605
https://pubmed.ncbi.nlm.nih.gov/15042605
Autor:
Joan Dusich, Tony Purchio, Yoko Oei, Yvette S. Hornig, Darlene E. Jenkins, Shang-Fan Yu, Pamela R. Contag
Publikováno v:
Clinicalexperimental metastasis. 20(8)
Bioluminescent imaging (BLI) permits sensitive in vivo detection and quantification of cells specifically engineered to emit visible light. Three stable human tumor cell lines engineered to express luciferase were assessed for their tumorigenicity in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62da8f2f8d52cd38e79bc5ffdf24704e
https://pubmed.ncbi.nlm.nih.gov/14713107
https://pubmed.ncbi.nlm.nih.gov/14713107
Publikováno v:
Clinicalexperimental metastasis. 20(8)
We used the bioluminescent human prostate carcinoma cell line PC-3M-luc-C6 to non-invasively monitor in vivo growth and response of tumors and metastasis before, during and after treatments. Our goal was to determine the utility of a luciferase-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f41df63095d139899db3764bf4d2fea3
https://pubmed.ncbi.nlm.nih.gov/14713108
https://pubmed.ncbi.nlm.nih.gov/14713108