Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Tony M. Raynham"'
Publikováno v:
The Journal of Organic Chemistry. 67:1802-1815
The Garner aldehyde-derived methylene alkene 5 and the corresponding benzyloxycarbonyl compound 25 undergo hydroboration with 9-BBN-H followed by palladium-catalyzed Suzuki coupling reactions with aryl and vinyl halides. After one-pot hydrolysis−ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab800ea72b29a4d70592ee1b23d7e202
https://doi.org/10.1021/jo010865a
https://doi.org/10.1021/jo010865a
Autor:
E.A. Conway, D.N. Hurst, Elizabeth Keech, HA Overton, J.R. Greening, A.D. Campbell, Maria Grazia Carr, N.S. Jennings, R.M. Dunsdon, Tony M. Raynham, J.M. Bennett, C.S. Wilkinson, S. Jordan, F.X. Wilson, Paul S. Jones, KP Stenson, P.B. Kay, J. King-Underwood, Tci Wilkinson, Ggm Canning, B. K. Handa, M.A. O'Brien, Attwood
Publikováno v:
Scopus-Elsevier
Hepatitis C virus (HCV) is the cause of the majority of transfusion-associated hepatitis and a significant proportion of community-acquired hepatitis worldwide. Infection by HCV frequently leads to persistent infections that result in a range of clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddcef90c45785e9a6eb633d040203827
https://doi.org/10.1177/095632029901000505
https://doi.org/10.1177/095632029901000505
Publikováno v:
Tetrahedron Letters. 40:5263-5266
The Garner aldehyde-derived methylene alkene has been hydroborated using 9-BBN and the resulting organoborane employed in palladium-catalysed Suzuki coupling reactions to produce, after hydrolysis-oxidation, a range of novel amino acids as their N-BO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e185c732371835c170629d452da9df8
https://doi.org/10.1016/s0040-4039(99)00997-1
https://doi.org/10.1016/s0040-4039(99)00997-1
Publikováno v:
Tetrahedron Letters. 39:4377-4380
The presence of the quinazolin-4(3H)-one (Q) ring in 1-(Q)-2-vinylaziridine (2) can be used to control the stereochemistry of the 3-membered ring-opening; participation by the quinazolinone carbonyl oxygen brings about ring-opening with retention of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2082249f798d69cd7e5250b9f123f18e
https://doi.org/10.1016/s0040-4039(98)00705-9
https://doi.org/10.1016/s0040-4039(98)00705-9
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :2783-2794
3-Amino-2-[(S)-1-hydroxy-2,2-dimethylpropyl]quinazolin-4(3H)-one 9 (Q2NH) was prepared in four steps from (S)-tert-leucine in 43% yield without the need for chromatography. The corresponding 3-acetoxyaminoquinazolinone 10 (Q2NHOAc), prepared in dichl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cc3ffbcf51f4e10f7822f11a49aeb99
https://doi.org/10.1039/a804377i
https://doi.org/10.1039/a804377i
Publikováno v:
Tetrahedron Letters. 39:497-500
The presence of the quinazolin-4(3H)-one ring (Q∗) in N-(Q∗)-aziridines facilitates ring-opening by nucleophiles: removal of the Q∗ group from enantiopure ring-opened products gives useful chirons.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::338874c054a512ff24213dca4828056e
https://doi.org/10.1016/s0040-4039(97)10586-x
https://doi.org/10.1016/s0040-4039(97)10586-x
Publikováno v:
Tetrahedron Letters. 38:505-508
Diastereoselective addition of nucleophiles to 1-(RCO)-substituted tricarbony η 4 -cyclohexadiene)iron(0) complexes, and a diastereoselective acid-induced rearrangement to form 1-(branched alkyl)-substituted tricarbonyl( η 5 -cyclohexadienyl)iron(1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58eba3c5cd7040c70ceca9f0d85b88df
https://doi.org/10.1016/s0040-4039(96)02360-x
https://doi.org/10.1016/s0040-4039(96)02360-x
Publikováno v:
Tetrahedron Letters. 37:2731-2734
Optimisation of Stille coupling between tricarbonyl[1,2,3,4-η-cyclohexadien-1-yl triflate]iron(0) and tributylvinyltin forms the 1-ethenyl-substituted tricarbonyliron complex in up to 81% yield. Coupling with trimethylsilylethyne in the presence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdf4a5e8ab4ba6f4a86ec5410e2db645
https://doi.org/10.1016/0040-4039(96)00373-5
https://doi.org/10.1016/0040-4039(96)00373-5
Publikováno v:
Tetrahedron Letters. 35:5303-5306
The addition of zinc(II)bromide reverses the diastereoselectivity of the diisobutyl-aluminium hydride (DIBAL-H) reduction of benzylidene sulphinamide R (S) R-(−)- 4 . The same reversal is not observed in the reactions of analogues lacking an amide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c200e136a98a6da4a41931b09879c5e4
https://doi.org/10.1016/s0040-4039(00)77091-2
https://doi.org/10.1016/s0040-4039(00)77091-2
Publikováno v:
Tetrahedron Letters. 43:2083-2085
(R)-3-Amino-2-[1-(2-hydroxyethoxy)ethyl]quinazolin-4(3H)-one 10 was prepared in 62% yield without the need for chromatography and O-cinnamoylated; reaction with lead tetra-acetate gave aziridine 12 as a single diastereoisomer in quantitative yield wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90acdf6e415ea8224028a65a2195778d
https://doi.org/10.1016/s0040-4039(02)00136-3
https://doi.org/10.1016/s0040-4039(02)00136-3