Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Tony Karlsborn"'
Autor:
Fredrik Palm, Ying Leng, Yu Shen, Tony Karlsborn, Tomas A Schiffer, Yun Wang, Shady Younis, Xuan Wang, K.T. Turpaev, Peter Bergsten, Jing Cen, Suling Huang, Anongnad Ngamjariyawat, Andris Elksnis, Nils Welsh
Publikováno v:
Clinical Science. 135:2243-2263
The protein tyrosine kinase inhibitor imatinib is used in the treatment of various malignancies but may also promote beneficial effects in the treatment of diabetes. The aim of the present investigation was to characterize the mechanisms by which ima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::960e46cb86e91f617f04b1d06d1613df
https://doi.org/10.1042/cs20210604
https://doi.org/10.1042/cs20210604
Publikováno v:
Metabolomics
Introduction The Elongator complex, comprising six subunits (Elp1p-Elp6p), is required for formation of 5-carbamoylmethyl (ncm5) and 5-methoxycarbonylmethyl (mcm5) side chains on wobble uridines in 11 out of 42 tRNA species in Saccharomyces cerevisia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec9f1282df19edac02d95e96f4aecbf9
http://europepmc.org/articles/PMC5037161
http://europepmc.org/articles/PMC5037161
Publikováno v:
RNA biology. 11(12)
Elongator is a 6 subunit protein complex highly conserved in eukaryotes. The role of this complex has been controversial as the pleiotropic phenotypes of Elongator mutants have implicated the complex in several cellular processes. However, in yeast t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ab4003a1b46d281f5a566424cfd2a18
https://pubmed.ncbi.nlm.nih.gov/25607684
https://pubmed.ncbi.nlm.nih.gov/25607684
Publikováno v:
Biochemical and Biophysical Research Communications. (3):441-445
Familial dysautonomia (FD) is a recessive neurodegenerative genetic disease. FD is caused by a mutation in the IKBKAP gene resulting in a splicing defect and reduced levels of full length IKAP protein. IKAP homologues can be found in all eukaryotes a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc69b02812c3758e1ddf2f89dfec0541