Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Tony J. Collins"'
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 11, Pp 1180-1191 (2019)
Abstract Chemotherapy‐induced peripheral neuropathy (PN) is a disorder damaging the peripheral nervous system (PNS) and represents one of the most common side effects of chemotherapy, negatively impacting the quality of life of patients to the exte
Externí odkaz:
https://doaj.org/article/3764edd4f1da44579dfe797072a729e3
Autor:
Lili Aslostovar, Allison L. Boyd, Mohammed Almakadi, Tony J. Collins, Darryl P. Leong, Rommel G. Tirona, Richard B. Kim, Jim A. Julian, Anargyros Xenocostas, Brian Leber, Mark N. Levine, Ronan Foley, Mickie Bhatia
Publikováno v:
Blood Advances, Vol 2, Iss 15, Pp 1935-1945 (2018)
Abstract: We completed a phase 1 dose-escalation trial to evaluate the safety of a dopamine receptor D2 (DRD2) antagonist thioridazine (TDZ), in combination with cytarabine. Thirteen patients 55 years and older with relapsed or refractory acute myelo
Externí odkaz:
https://doaj.org/article/65462c7955b0444b8aa80b9a26bdee79
Autor:
Jennifer C. Reid, Borko Tanasijevic, Diana Golubeva, Allison L. Boyd, Deanna P. Porras, Tony J. Collins, Mickie Bhatia
Publikováno v:
Stem Cell Reports, Vol 10, Iss 5, Pp 1625-1641 (2018)
Summary: Human pluripotent stem cells (hPSCs) generate hematopoietic progenitor cells (HPCs) but fail to engraft xenograft models used to detect adult/somatic hematopoietic stem cells (HSCs) from donors. Recent progress to derive hPSC-derived HSCs ha
Externí odkaz:
https://doaj.org/article/ccabb1b5765542a4a5b34f9e544c110d
Autor:
Jong-Hee Lee, Sarah Laronde, Tony J. Collins, Zoya Shapovalova, Borko Tanasijevic, Jamie D. McNicol, Aline Fiebig-Comyn, Yannick D. Benoit, Jung Bok Lee, Ryan R. Mitchell, Mickie Bhatia
Publikováno v:
Cell Reports, Vol 19, Iss 1, Pp 20-35 (2017)
Human pluripotent stem cells (hPSCs) have been reported in naive and primed states. However, the ability to generate mature cell types remains the imperative property for utility of hPSCs. Here, we reveal that the naive state enhances self-renewal wh
Externí odkaz:
https://doaj.org/article/632c81e24b1a4140a186435928fb0d4b
Autor:
Jong-Hee Lee, Ryan R. Mitchell, Jamie D. McNicol, Zoya Shapovalova, Sarah Laronde, Borko Tanasijevic, Chloe Milsom, Fanny Casado, Aline Fiebig-Comyn, Tony J. Collins, Karun K. Singh, Mickie Bhatia
Publikováno v:
Cell Reports, Vol 11, Iss 9, Pp 1367-1376 (2015)
The clinical applicability of direct cell fate conversion depends on obtaining tissue from patients that is easy to harvest, store, and manipulate for reprogramming. Here, we generate induced neural progenitor cells (iNPCs) from neonatal and adult pe
Externí odkaz:
https://doaj.org/article/b11aa922158d4166b81be9280ad2f0aa
Publikováno v:
Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 8, Iss 11, Pp 1180-1191 (2019)
Stem Cells Translational Medicine, Vol 8, Iss 11, Pp 1180-1191 (2019)
Chemotherapy-induced peripheral neuropathy (PN) is a disorder damaging the peripheral nervous system (PNS) and represents one of the most common side effects of chemotherapy, negatively impacting the quality of life of patients to the extent of withd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0f34b61433b18f94a724435300eeba2
https://doi.org/10.1002/sctm.19-0054
https://doi.org/10.1002/sctm.19-0054
Autor:
Borhane Guezguez, Tony J. Collins, Aline Fiebig, Jung Bok Lee, Jamie D. McNicol, Mick Bhatia, Douglas R. Boreham, Steve Dingwall
Publikováno v:
Oncotarget
Scopus-Elsevier
Scopus-Elsevier
// Steve Dingwall 1, 2 , Jung Bok Lee 1 , Borhane Guezguez 1 , Aline Fiebig 1 , Jamie McNicol 1 , Douglas Boreham 3 , Tony J. Collins 1, 4 , Mick Bhatia 1, 2, 4 1 McMaster Stem Cell and Cancer Research Institute, Michael G. DeGroote School of Medicin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db3a0f52db177b360c0b8f4207528baa
https://doi.org/10.18632/oncotarget.4165
https://doi.org/10.18632/oncotarget.4165
Autor:
Ronan Foley, Mickie Bhatia, Mark Levine, Darryl P. Leong, Brian Leber, Richard B. Kim, Mohammed Almakadi, Rommel G. Tirona, Anargyros Xenocostas, Jim A. Julian, Allison L. Boyd, Tony J. Collins, Lili Aslostovar
Publikováno v:
Paediatrics Publications
We completed a phase 1 dose-escalation trial to evaluate the safety of a dopamine receptor D2 (DRD2) antagonist thioridazine (TDZ), in combination with cytarabine. Thirteen patients 55 years and older with relapsed or refractory acute myeloid leukemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ff7b9ad8173ddf9b836387dcfa4ecb
https://doi.org/10.1182/bloodadvances.2018015677
https://doi.org/10.1182/bloodadvances.2018015677
Autor:
Mickie Bhatia, Allison L. Boyd, Jennifer C. Reid, Tony J. Collins, Deanna P. Porras, Borko Tanasijevic, Diana Golubeva
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 10, Iss 5, Pp 1625-1641 (2018)
Stem Cell Reports, Vol 10, Iss 5, Pp 1625-1641 (2018)
Summary Human pluripotent stem cells (hPSCs) generate hematopoietic progenitor cells (HPCs) but fail to engraft xenograft models used to detect adult/somatic hematopoietic stem cells (HSCs) from donors. Recent progress to derive hPSC-derived HSCs has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc539a3ba59823159b53dc7e37570e8
http://europepmc.org/articles/PMC5995456
http://europepmc.org/articles/PMC5995456
Autor:
Christopher J. Bergin, Kinga Vojnits, Borko Tanasijevic, Zoya Shapovalova, Deanna P. Porras, Aïcha Zouggar, Meaghan Doyle, Luca Orlando, Angelique N. Masibag, Kalinka Koteva, Juan L. García-Rodríguez, Jagdish Suresh Patel, Jennifer Russell, Allison L. Boyd, Wenliang Wang, Ryan R. Mitchell, Tony J. Collins, Lili Aslostovar, Mickie Bhatia, Jakob Magolan, Gerard D. Wright, Yannick D. Benoit, Fanny L. Casado, Lakshmana K. Kinthada, Justin D. Lu, Sara N. Andres, Cody Caba
Publikováno v:
Cell Chem Biol
Summary Natural products (NPs) encompass a rich source of bioactive chemical entities. Here, we used human cancer stem cells (CSCs) in a chemical genomics campaign with NP chemical space to interrogate extracts from diverse strains of actinomycete fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc4b649220a9143bb55c542d4a9a1a0
https://doi.org/10.1016/j.chembiol.2021.04.014
https://doi.org/10.1016/j.chembiol.2021.04.014