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pro vyhledávání: '"Tony I. Lee"'
Autor:
Christopher M. Tegley, Chi-Hwei Lin, Xianghong Wang, Tae-Seong Kim, Tony I. Lee, Jennifer Dao, Christopher Mohr, Sandra Ross, Andrew Hague, Andrew Tasker, Steven R. Jordan, Philip Tagari, Brian Lian, Carol Mayeda, Teresa L. Burgess, Vellarkad N. Viswanadhan, Janet Cheetham, Yi-xin Qian
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:87-90
A series of (4-piperidinylphenyl)aminoethyl amides based on dipeptide anilines were synthesized and tested against cathepsin K, cathepsin L and cathepsin B. These new non-covalent inhibitors exhibited single-digit nM inhibition of the cysteine protea