Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Tony Hayek"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7789 (2024)
Excessive calorie intake leads to mitochondrial overload and triggers metabolic inflexibility and insulin resistance. In this study, we examined how attenuated p38α activity affects glucose and fat metabolism in the skeletal muscles of mice on a hig
Externí odkaz:
https://doaj.org/article/1da2188527c041eda432186aaf00fe84
Autor:
Oren Rom, Yuhao Liu, Alexandra C. Finney, Alia Ghrayeb, Ying Zhao, Yousef Shukha, Lu Wang, Krishani K. Rajanayake, Sandeep Das, Nabil A. Rashdan, Natan Weissman, Luisa Delgadillo, Bo Wen, Minerva T. Garcia-Barrio, Michael Aviram, Christopher G. Kevil, Arif Yurdagul, Jr., Christopher B. Pattillo, Jifeng Zhang, Duxin Sun, Tony Hayek, Eyal Gottlieb, Inbal Mor, Y Eugene Chen
Publikováno v:
Redox Biology, Vol 52, Iss , Pp 102313- (2022)
Lower circulating levels of glycine are consistently reported in association with cardiovascular disease (CVD), but the causative role and therapeutic potential of glycine in atherosclerosis, the underlying cause of most CVDs, remain to be establishe
Externí odkaz:
https://doaj.org/article/c0ac47e2e99749538883049d2ad1e8c9
Autor:
Kamal Makhoul, Yousef Shukha, Lana Abu Hanna, Samy Nitecki, Maxim Leiderman, Tony Hayek, Shadi Hamoud
Publikováno v:
International Journal of Infectious Diseases, Vol 106, Iss , Pp 401-404 (2021)
Background: For more than a year, health systems all over the world have been combating the global coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The disease was first described i
Externí odkaz:
https://doaj.org/article/e1522d67f66f4281b9a7ae5d951d1d95
Publikováno v:
Antioxidants, Vol 11, Iss 10, p 2058 (2022)
Paraoxonase 1 (PON1) plays a role in regulating reverse cholesterol transport and has antioxidative, anti-inflammatory, antiapoptotic, vasodilative, and antithrombotic activities. Scientists are currently focused on the modulation of PON1 expression
Externí odkaz:
https://doaj.org/article/c71718d82861452db49e957bcd64adda
Autor:
Yuhao Liu, Ying Zhao, Yousef Shukha, Haocheng Lu, Lu Wang, Zhipeng Liu, Cai Liu, Yang Zhao, Huilun Wang, Guizhen Zhao, Wenying Liang, Yanbo Fan, Lin Chang, Arif Yurdagul, Jr., Christopher B. Pattillo, A. Wayne Orr, Michael Aviram, Bo Wen, Minerva T. Garcia-Barrio, Jifeng Zhang, Wanqing Liu, Duxin Sun, Tony Hayek, Y. Eugene Chen, Oren Rom
Publikováno v:
Cell Reports, Vol 36, Iss 4, Pp 109420- (2021)
Summary: Dysregulated glycine metabolism is emerging as a common denominator in cardiometabolic diseases, but its contribution to atherosclerosis remains unclear. In this study, we demonstrate impaired glycine-oxalate metabolism through alanine-glyox
Externí odkaz:
https://doaj.org/article/cd26e64f714e496680a0eaa2799a0feb
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 18, p 6480 (2020)
Skeletal muscles respond to environmental and physiological changes by varying their size, fiber type, and metabolic properties. P38 mitogen-activated protein kinase (MAPK) is one of several signaling pathways that drive the metabolic adaptation of s
Externí odkaz:
https://doaj.org/article/d858107768ee43a5a9fb2ddd7bdc76dd
Autor:
Hila Korach-Rechtman, Oren Rom, Lirane Mazouz, Shay Freilich, Helana Jeries, Tony Hayek, Michael Aviram, Yechezkel Kashi
Publikováno v:
Microorganisms, Vol 8, Iss 4, p 486 (2020)
During the last few decades there has been a staggering rise in human consumption of soybean-oil (SO). The microbiome and specific taxa composing it are dramatically affected by diet; specifically, by high-fat diets. Increasing evidence indicates the
Externí odkaz:
https://doaj.org/article/4f3ea1e31195429f81f01ad3b1290c82
Publikováno v:
International Journal of Endocrinology, Vol 2015 (2015)
Inflammatory processes are involved in atherosclerosis development. Macrophages play a major role in the early atherogenesis, and they are present in the atherosclerotic lesion in two phenotypes: proinflammatory (M1) or anti-inflammatory (M2). Paraox
Externí odkaz:
https://doaj.org/article/8ab209fe0277420c97cfb19b1144681b
Autor:
Maxim Leiderman, Tony Hayek, Shadi Hamoud, Samy Nitecki, Kamal Makhoul, Lana Abu Hanna, Yousef Shukha
Publikováno v:
International Journal of Infectious Diseases, Vol 106, Iss, Pp 401-404 (2021)
International Journal of Infectious Diseases
International Journal of Infectious Diseases
BACKGROUND: For more than a year, health systems all over the world have been combating the global coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The disease was first described i
Publikováno v:
Journal of Cardiovascular Medicine and Cardiology. :221-225
Aims: The aim of our study was to analyze the effect of serum derived from patients with chest pain, with or without significant atherosclerosis, on J774A.1 macrophages cholesterol metabolism. Methods: Thirty-nine patients with chest pain underwent C