Monoaminergic impairment in Down syndrome with Alzheimer's disease compared to early‐onset Alzheimer's disease

Autor: Alain D. Dekker, Yannick Vermeiren, Maria Carmona‐Iragui, Bessy Benejam, Laura Videla, Ellen Gelpi, Tony Aerts, Debby Van Dam, Susana Fernández, Alberto Lleó, Sebastian Videla, Anne Sieben, Jean‐Jacques Martin, Netherlands Brain Bank, Rafael Blesa, Juan Fortea, Peter P. De Deyn

Publikováno v: Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 10, Iss 1, Pp 99-111 (2018)

Abstract Introduction People with Down syndrome (DS) are at high risk for Alzheimer's disease (AD). Defects in monoamine neurotransmitter systems are implicated in DS and AD but have not been comprehensively studied in DS. Methods Noradrenaline, adre

Externí odkaz: https://doaj.org/article/d4ab168ebe3f432eb3c4e7d2baaea7d3

Monoaminergic impairment in Down syndrome with Alzheimer's disease compared to early‐onset Alzheimer's disease

Autor: Debby Van Dam, Alberto Lleó, Anne Sieben, Tony Aerts, Ellen Gelpi, Sebastián Videla, Maria Carmona-Iragui, Jean-Jacques Martin, Yannick Vermeiren, Bessy Benejam, Peter Paul De Deyn, Alain D. Dekker, Susana Fernández, Rafael Blesa, Laura Videla, Juan Fortea

Publikováno v: Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 10, Iss 1, Pp 99-111 (2018)
Alzheimer's & dementia (Amsterdam, Netherlands), 10, 99-111
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring
Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, 10, 99-111
Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring 10 (2018)
Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, 10, 99-111. Elsevier B.V.
Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring

Introduction People with Down syndrome (DS) are at high risk for Alzheimer's disease (AD). Defects in monoamine neurotransmitter systems are implicated in DS and AD but have not been comprehensively studied in DS. Methods Noradrenaline, adrenaline, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ea77c83b2d261aae4977b0622cc1376
https://doaj.org/article/d4ab168ebe3f432eb3c4e7d2baaea7d3

[P4–405]: MONOAMINERGIC CORRELATES OF DISINHIBITED BEHAVIOURS IN THE NOVEL TAU58/4 TRANSGENIC MOUSE MODEL FOR TAUOPATHY

Autor: Yannick Vermeiren, Tony Aerts, Debby Van Dam, Peter Paul De Deyn, Femke Valkenburg

Publikováno v: Alzheimer's & Dementia. 13

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f097d587a575b8d60fd1e64e073098b8
https://doi.org/10.1016/j.jalz.2017.07.565

Brain Serotonergic and Noradrenergic Deficiencies in Behavioral Variant Frontotemporal Dementia Compared to Early-Onset Alzheimer's Disease

Autor: Anne Sieben, Jana Janssens, Peter Paul De Deyn, Yannick Vermeiren, Jean-Jacques Martin, Debby Van Dam, Tony Aerts

Publikováno v: Journal of Alzheimer's Disease, 53(3), 1079-1096
Journal of Alzheimer's disease
Journal of Alzheimer's Disease 53 (2016) 3
Journal of Alzheimer’s Disease, 53(3), 1079-1096. IOS Press

Routinely prescribed psychoactive drugs in behavioral variant frontotemporal dementia (FTD) for improvement of (non) cognitive symptoms are primarily based on monoamine replacement or augmentation strategies. These were, however, initially intended t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c028c528a7db1015dfb9bcc5fe30e3
https://research.wur.nl/en/publications/brain-serotonergic-and-noradrenergic-deficiencies-in-behavioral-v

The monoaminergic footprint of depression and psychosis in dementia with Lewy bodies compared to Alzheimer's disease

Autor: Peter Paul De Deyn, Sebastiaan Engelborghs, Jean-Jacques Martin, Yannick Vermeiren, Tony Aerts, Debby Van Dam

Publikováno v: Alzheimer's Research & Therapy
Alzheimers research & therapy, 7(1):7, 1-18. BioMed Central Ltd.
Alzheimer's research & therapy
Alzheimer's Research and Therapy, 7(1)
Alzheimer's Research and Therapy 7 (2015) 1

Introduction: Depression and psychosis are two of the most severe neuropsychiatric symptoms (NPS) in dementia with Lewy bodies (DLB) and Alzheimer's disease (AD). Both NPS have negative effects on cognitive performance and life expectancy. The curren

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eba74f7469649dfb545734b38729f3b4
https://biblio.vub.ac.be/vubir/the-monoaminergic-footprint-of-depression-and-psychosis-in-dementia-with-lewy-bodies-compared-to-alzheimers-disease(fc2cb3fa-4510-494f-b86f-0e81aa4442fb).html