Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Tony, Lefebvre"'
Publikováno v:
Oncogenesis, Vol 12, Iss 1, Pp 1-10 (2023)
Abstract An accelerated de novo lipogenesis (DNL) flux is a common characteristic of cancer cells required to sustain a high proliferation rate. The DNL enzyme fatty acid synthase (FASN) is overexpressed in many cancers and is pivotal for the increas
Externí odkaz:
https://doaj.org/article/ccabb9c0240746f0a25715b4a0ef91a0
Autor:
Jodie Scache, Vincent Rigolot, Cédric Lion, Marlène Mortuaire, Tony Lefebvre, Christophe Biot, Anne-Sophie Vercoutter-Edouart
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Sialylation of cell surface glycans plays an essential role in cell–cell interaction and communication of cells with their microenvironment. Among the tools that have been developed for the study of sialylation in living cells, metabolic o
Externí odkaz:
https://doaj.org/article/addd208bd7aa43c68797c8f64960ee45
Autor:
Céline Schulz, Quentin Lemaire, Alexandre Berthier, Amandine Descat, Mostafa Kouach, Anne‐Sophie Vercoutter‐Edouart, Ikram El Yazidi‐Belkoura, Stéphan Hardivillé, Jean‐François Goossens, Philippe Lefebvre, Tony Lefebvre
Publikováno v:
Natural Sciences, Vol 3, Iss 2, Pp n/a-n/a (2023)
Abstract O‐GlcNAcylation is a post‐translational modification belonging to the large group of glycosylations. It consists of the modification of cytoplasmic, nuclear, and mitochondrial proteins with a single N‐acetylglucosamine residue by O‐G
Externí odkaz:
https://doaj.org/article/ef8c5d8469834b5285cbfe60fe031f8c
Autor:
Awatef Ben Ahmed, Quentin Lemaire, Jodie Scache, Christophe Mariller, Tony Lefebvre, Anne-Sophie Vercoutter-Edouart
Publikováno v:
Cells, Vol 12, Iss 10, p 1396 (2023)
The transport of proteins between the different cellular compartments and the cell surface is governed by the secretory pathway. Alternatively, unconventional secretion pathways have been described in mammalian cells, especially through multivesicula
Externí odkaz:
https://doaj.org/article/877090e155b54fdda4964335cfda5d32
Autor:
Tarik Issad, Tony Lefebvre
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/da2f57fc33f44123b319d4652a1b84dc
Autor:
Mattis Kupferschmid, Moyira Osny Aquino-Gil, Hosam Shams-Eldin, Jörg Schmidt, Nao Yamakawa, Frédéric Krzewinski, Ralph T. Schwarz, Tony Lefebvre
Publikováno v:
Malaria Journal, Vol 16, Iss 1, Pp 1-11 (2017)
Abstract Background Post-translational modifications (PTMs) constitute a huge group of chemical modifications increasing the complexity of the proteomes of living beings. PTMs have been discussed as potential anti-malarial drug targets due to their i
Externí odkaz:
https://doaj.org/article/b2a672dbeae84837bb455042b2a32b2f
Autor:
Gabriela Fuentes-García, M. Cristina Castañeda-Patlán, Anne-Sophie Vercoutter-Edouart, Tony Lefebvre, Martha Robles-Flores
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
The dynamic O-linked-N-acetylglucosamine posttranslational modification of nucleocytoplasmic proteins has emerged as a key regulator of diverse cellular processes including several hallmarks of cancer. However, the role played by this modification in
Externí odkaz:
https://doaj.org/article/6d5ec206710b470d8d136c27c3b549af
Autor:
Elia Torres-Gutiérrez, Yobana Pérez-Cervera, Luc Camoin, Edgar Zenteno, Moyira Osny Aquino-Gil, Tony Lefebvre, Margarita Cabrera-Bravo, Olivia Reynoso-Ducoing, Martha Irene Bucio-Torres, Paz María Salazar-Schettino
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Originally an anthropozoonosis in the Americas, Chagas disease has spread from its previous borders through migration. It is caused by the protozoan Trypanosoma cruzi. Differences in disease severity have been attributed to a natural pleomorphism in
Externí odkaz:
https://doaj.org/article/dd1e8948dcc4492c9c42b551aeb61b5a
Autor:
Louis Masclef, Vanessa Dehennaut, Marlène Mortuaire, Céline Schulz, Maïté Leturcq, Tony Lefebvre, Anne-Sophie Vercoutter-Edouart
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Cyclin D1 is the regulatory partner of the cyclin-dependent kinases (CDKs) CDK4 or CDK6. Once associated and activated, the cyclin D1/CDK complexes drive the cell cycle entry and G1 phase progression in response to extracellular signals. To ensure th
Externí odkaz:
https://doaj.org/article/07a326caad4447558c77d69d9338854c
Autor:
Céline Schulz, Quentin Lemaire, Alexandre Berthier, Amandine Descat, Mostafa Kouach, Anne‐Sophie Vercoutter‐Edouart, Ikram El Yazidi‐Belkoura, Stéphan Hardivillé, Jean‐François Goossens, Philippe Lefebvre, Tony Lefebvre
Publikováno v:
Natural Sciences. 3