Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Tony, Jourdan"'
Autor:
Trinh-Le-Vi Kieu, Léa Pierre, Valentin Derangère, Sabrina Perrey, Caroline Truntzer, Antoine Jalil, Sébastien Causse, Emma Groetz, Adélie Dumont, Laura Guyard, Laurent Arnould, Jean-Paul Pais de Barros, Lionel Apetoh, Cédric Rébé, Emeric Limagne, Tony Jourdan, Laurent Demizieux, David Masson, Charles Thomas, François Ghiringhelli, Mickaël Rialland
Publikováno v:
Cell Death and Disease, Vol 13, Iss 9, Pp 1-18 (2022)
Abstract Metastatic breast cancer cannot be cured, and alteration of fatty acid metabolism contributes to tumor progression and metastasis. Here, we were interested in the elongation of very long-chain fatty acids protein 5 (Elovl5) in breast cancer.
Externí odkaz:
https://doaj.org/article/e46e8fef42814a68866b78b5481c0414
Autor:
Gergő Szanda, Tony Jourdan, Éva Wisniewski, Resat Cinar, Grzegorz Godlewski, Anikó Rajki, Jie Liu, Lee Chedester, Bence Szalai, András Dávid Tóth, Eszter Soltész-Katona, László Hunyady, Asuka Inoue, Viktória Bea Horváth, András Spät, Joseph Tam, George Kunos
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107207- (2023)
Summary: Molecular interactions between anorexigenic leptin and orexigenic endocannabinoids, although of great metabolic significance, are not well understood. We report here that hypothalamic STAT3 signaling in mice, initiated by physiological eleva
Externí odkaz:
https://doaj.org/article/fdec89d7da924457af4fc198282c561d
Autor:
Laetitia Jacquot, Océane Pointeau, Célia Roger-Villeboeuf, Patricia Passilly-Degrace, Rim Belkaid, Isaline Regazzoni, Julia Leemput, Chloé Buch, Laurent Demizieux, Bruno Vergès, Pascal Degrace, Glenn Crater, Tony Jourdan
Publikováno v:
Frontiers in Nephrology, Vol 3 (2023)
ObjectiveThis study assessed the efficacy of INV-202, a novel peripherally restricted cannabinoid type-1 receptor (CB1R) inverse agonist, in a streptozotocin-induced type-1 diabetes nephropathy mouse model.MethodsDiabetes was induced in 8-week-old C5
Externí odkaz:
https://doaj.org/article/97f8a94235a049d3a30516336677a728
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/e678667d85134da5bea64f5a7985f4bf
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/a2b0a213e87d48f198c6ef1bfd4a463d
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/ad482c156320441ba9f2df50c10673a2
Autor:
Chloé Buch, Tania Muller, Julia Leemput, Patricia Passilly-Degrace, Pablo Ortega-Deballon, Jean-Paul Pais de Barros, Bruno Vergès, Tony Jourdan, Laurent Demizieux, Pascal Degrace
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
White adipose tissue (WAT) possesses the endocannabinoid system (ECS) machinery and produces the two major endocannabinoids (ECs), arachidonoylethanolamide (AEA) and 2-arachidonoylglycerol (2-AG). Accumulating evidence indicates that WAT cannabinoid
Externí odkaz:
https://doaj.org/article/7e486bffc6314cd4b15c94c3c29344b2
Autor:
Resat Cinar, Joshua K. Park, Charles N. Zawatsky, Nathan J. Coffey, Steven P. Bodine, Jasmina Abdalla, Tadafumi Yokoyama, Tony Jourdan, Lindsey Jay, Mei Xing G. Zuo, Kevin J. O'Brien, Junfeng Huang, Ken Mackie, Asaf Alimardanov, Malliga R. Iyer, William A. Gahl, George Kunos, Bernadette R. Gochuico, May Christine V. Malicdan
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 7, Pp n/a-n/a (2021)
Abstract Hermansky–Pudlak syndrome (HPS) is a rare genetic disorder which, in its most common and severe form, HPS‐1, leads to fatal adult‐onset pulmonary fibrosis (PF) with no effective treatment. We evaluated the role of the endocannabinoid/C
Externí odkaz:
https://doaj.org/article/6b58354bc8cd41de976ad8a5c91da796
Autor:
Thibaut Bourgeois, Antoine Jalil, Charles Thomas, Charlène Magnani, Naig Le Guern, Thomas Gautier, Jean-Paul Pais de Barros, Victoria Bergas, Hélène Choubley, Loïc Mazzeo, Louise Menegaut, Lorène Josiane Lebrun, Kévin Van Dongen, Marion Xolin, Tony Jourdan, Chloé Buch, Jérome Labbé, Philippe Saas, Laurent Lagrost, David Masson, Jacques Grober
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100013- (2021)
Recent studies have highlighted an important role for lysophosphatidylcholine acyltransferase 3 (LPCAT3) in controlling the PUFA composition of cell membranes in the liver and intestine. In these organs, LPCAT3 critically supports cell-membrane-assoc
Externí odkaz:
https://doaj.org/article/83c4b2a37855418097b19c9a61a1428a
Autor:
Tania Muller, Laurent Demizieux, Stéphanie Troy-Fioramonti, Chloé Buch, Julia Leemput, Christine Belloir, Jean-Paul Pais de Barros, Tony Jourdan, Patricia Passilly-Degrace, Xavier Fioramonti, Anne-Marie Le Bon, Bruno Vergès, Jean-Michel Robert, Pascal Degrace
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 6, p 2923 (2022)
Targeting cannabinoid 1 receptors (CB1R) with peripherally restricted antagonists (or inverse agonists) shows promise to improve metabolic disorders associated with obesity. In this context, we designed and synthetized JM-00266, a new CB1R blocker wi
Externí odkaz:
https://doaj.org/article/b2f6bd758f174af982d56a610f737916