Synthesis, characterization, DNA binding, topoisomerase inhibition, and apoptosis induction studies of a novel cobalt(III) complex with a thiosemicarbazone ligand.

Autor: Beebe SJ; The Frank Reidy Center for Bioelectrics, 4211 Monarch Way, Suite 300, Norfolk, VA 23529, USA., Celestine MJ; Department of Chemistry and Biochemistry, Old Dominion University, 4541 Hampton Boulevard, Norfolk, VA 23529, USA., Bullock JL; Department of Chemistry and Biochemistry, Old Dominion University, 4541 Hampton Boulevard, Norfolk, VA 23529, USA., Sandhaus S; Department of Chemistry and Biochemistry, Biomolecular Sciences Institute, Florida International University, 11200 SW 8th St., Miami, FL 33199, USA., Arca JF; Department of Chemistry and Biochemistry, The University of Southern Mississippi, 118 College Drive, Hattiesburg, MS 39406, USA., Cropek DM; U.S. Army Corps of Engineers, Construction Engineering Research Laboratory, Champaign, IL 61822, USA., Ludvig TA; Department of Chemistry and Biochemistry, Old Dominion University, 4541 Hampton Boulevard, Norfolk, VA 23529, USA., Foster SR; Department of Chemistry and Biochemistry, Old Dominion University, 4541 Hampton Boulevard, Norfolk, VA 23529, USA., Clark JS; Department of Chemistry and Biochemistry, Old Dominion University, 4541 Hampton Boulevard, Norfolk, VA 23529, USA., Beckford FA; The University of Virginia's College at Wise, 1 College Avenue, Wise, VA 24293, USA., Tano CM; Department of Chemistry and Biochemistry, Old Dominion University, 4541 Hampton Boulevard, Norfolk, VA 23529, USA., Tonsel-White EA; Department of Chemistry and Biochemistry, Old Dominion University, 4541 Hampton Boulevard, Norfolk, VA 23529, USA., Gurung RK; Department of Chemistry and Biochemistry, Old Dominion University, 4541 Hampton Boulevard, Norfolk, VA 23529, USA., Stankavich CE; Department of Chemistry and Biochemistry, Old Dominion University, 4541 Hampton Boulevard, Norfolk, VA 23529, USA., Tse-Dinh YC; Department of Chemistry and Biochemistry, Biomolecular Sciences Institute, Florida International University, 11200 SW 8th St., Miami, FL 33199, USA., Jarrett WL; School of Polymers and High-Performance Materials, The University of Southern Mississippi, 118 College Drive, #5050, Hattiesburg, MS 39406, USA., Holder AA; Department of Chemistry and Biochemistry, Old Dominion University, 4541 Hampton Boulevard, Norfolk, VA 23529, USA. Electronic address: aholder@odu.edu.

Publikováno v: Journal of inorganic biochemistry [J Inorg Biochem] 2020 Feb; Vol. 203, pp. 110907. Date of Electronic Publication: 2019 Nov 02.