An alphavirus-based adjuvant enhances serum and mucosal antibodies, T cells, and protective immunity to influenza virus in neonatal mice.

Autor: Khalil SM; Global Vaccines Inc., Research Triangle Park, North Carolina, USA Department of Microbiology and Immunology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Tonkin DR; Global Vaccines Inc., Research Triangle Park, North Carolina, USA., Snead AT; Global Vaccines Inc., Research Triangle Park, North Carolina, USA., Parks GD; Department of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA., Johnston RE; Global Vaccines Inc., Research Triangle Park, North Carolina, USA., White LJ; Global Vaccines Inc., Research Triangle Park, North Carolina, USA ljwhite@globalvaccines.org.

Publikováno v: Journal of virology [J Virol] 2014 Aug; Vol. 88 (16), pp. 9182-96. Date of Electronic Publication: 2014 Jun 04.

Infected dendritic cells are sufficient to mediate the adjuvant activity generated by Venezuelan equine encephalitis virus replicon particles.

Autor: Tonkin DR; Global Vaccines Inc, 7020 Kit Creek Rd, Ste. 240, PO Box 14827, Research Triangle Park, NC 27709, USA. dtonkin@globalvaccines.org, Whitmore A, Johnston RE, Barro M

Publikováno v: Vaccine [Vaccine] 2012 Jun 22; Vol. 30 (30), pp. 4532-42. Date of Electronic Publication: 2012 Apr 21.

Regulatory T cells enter the pancreas during suppression of type 1 diabetes and inhibit effector T cells and macrophages in a TGF-beta-dependent manner.

Autor: Tonkin DR; Department of Immunology, University of Colorado Denver and National Jewish Health, Denver, CO 80206, USA., Haskins K

Publikováno v: European journal of immunology [Eur J Immunol] 2009 May; Vol. 39 (5), pp. 1313-22.

Activation and tolerance in CD4(+) T cells reactive to an immunoglobulin variable region.

Autor: Snyder CM; Integrated Department of Immunology, National Jewish Medical and Research Center and University of Colorado School of Medicine, 1400 Jackson St., Denver, CO 80206, USA., Aviszus K, Heiser RA, Tonkin DR, Guth AM, Wysocki LJ

Publikováno v: The Journal of experimental medicine [J Exp Med] 2004 Jul 05; Vol. 200 (1), pp. 1-11. Date of Electronic Publication: 2004 Jun 28.