Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tonje Lien"'
Autor:
Johan Staaf, Jari Häkkinen, Cecilia Hegardt, Lao H. Saal, Siker Kimbung, Ingrid Hedenfalk, Tonje Lien, Therese Sørlie, Bjørn Naume, Hege Russnes, Rachel Marcone, Ayyakkannu Ayyanan, Cathrin Brisken, Rebecka R. Malterling, Bengt Asking, Helena Olofsson, Henrik Lindman, Pär-Ola Bendahl, Anna Ehinger, Christer Larsson, Niklas Loman, Lisa Rydén, Martin Malmberg, Åke Borg, Johan Vallon-Christersson
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-17 (2022)
Abstract Multigene assays for molecular subtypes and biomarkers can aid management of early invasive breast cancer. Using RNA-sequencing we aimed to develop single-sample predictor (SSP) models for clinical markers, subtypes, and risk of recurrence (
Externí odkaz:
https://doaj.org/article/d2e56c524d0b4a448d746df4499518bd
Autor:
Xavier Tekpli, Tonje Lien, Andreas Hagen Røssevold, Daniel Nebdal, Elin Borgen, Hege Oma Ohnstad, Jon Amund Kyte, Johan Vallon-Christersson, Marie Fongaard, Eldri Undlien Due, Lisa Gregusson Svartdal, My Anh Tu Sveli, Øystein Garred, OSBREAC, Arnoldo Frigessi, Kristine Kleivi Sahlberg, Therese Sørlie, Hege G. Russnes, Bjørn Naume, Vessela N. Kristensen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
In breast cancer, the immune infiltration of the tumour associates with clinical outcome. Here, the authors infer immune context based on gene expression data and identify a new independent subtype linked to pro-tumorigenic immune infiltration.
Externí odkaz:
https://doaj.org/article/77641556908e44e9aa2cd197f5b2e87b
Autor:
Haifeng Xu, Tonje Lien, Helga Bergholtz, Thomas Fleischer, Lounes Djerroudi, Anne Vincent-Salomon, Therese Sørlie, Tero Aittokallio
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Ductal carcinoma in situ (DCIS) is a preinvasive form of breast cancer with a highly variable potential of becoming invasive and affecting mortality of the patients. Due to the lack of accurate markers of disease progression, many women with detected
Externí odkaz:
https://doaj.org/article/0dd17cb3d65b48cbb58036c27bdb4198
Publikováno v:
Journal of mammary gland biology and neoplasia
Breast cancers in humans belong to one of several intrinsic molecular subtypes each with different tumor biology and different clinical impact. Mammary gland tumors in dogs are proposed as a relevant comparative model for human breast cancer; however
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23577100723143e0c80b3df730db63db
https://doi.org/10.1007/s10911-022-09523-9
https://doi.org/10.1007/s10911-022-09523-9
Autor:
Andreas Hagen Røssevold, My Anh Tu Sveli, Xavier Tekpli, Lisa Gregusson Svartdal, Eldri U. Due, Vessela N. Kristensen, Arnoldo Frigessi, Jon Amund Kyte, Therese Sørlie, Osbreac, Daniel Nebdal, Johan Vallon-Christersson, Elin Borgen, Marie Fongaard, Tonje Lien, Hege O. Ohnstad, Bjørn Naume, Hege G. Russnes, Kristine Kleivi Sahlberg, Øystein Garred
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
How mixtures of immune cells associate with cancer cell phenotype and affect pathogenesis is still unclear. In 15 breast cancer gene expression datasets, we invariably identify three clusters of patients with gradual levels of immune infiltration. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce309b8390b16dd520085ecfdd348180
http://link.springer.com/article/10.1038/s41467-019-13329-5
http://link.springer.com/article/10.1038/s41467-019-13329-5
Autor:
Xu, Haifeng, Lillebergen, Tonje Lien, Bergholtz, Helga, Fleischer, Thomas, Djerroudi, Lounes, Vincent-Salomon, Anne, Sørlie, Therese, Aittokallio, Tero Antero
Publikováno v:
Xu, Haifeng Lillebergen, Tonje Lien Bergholtz, Helga Fleischer, Thomas Djerroudi, Lounes Vincent-Salomon, Anne Sørlie, Therese Aittokallio, Tero Antero . Multi-omics marker analysis enables early prediction of breast tumor progression. Frontiers in Genetics. 2021, 12, 1-14
Frontiers in Genetics
Frontiers in Genetics
Externí odkaz:
http://hdl.handle.net/10852/89964
https://www.duo.uio.no/bitstream/handle/10852/89964/1/fgene-12-670749.pdf
https://www.duo.uio.no/bitstream/handle/10852/89964/1/fgene-12-670749.pdf
BackgroundIdentifying gene interactions is a topic of great importance in genomics, and approaches based on network models provide a powerful tool for studying these. Assuming a Gaussian graphical model, a gene association network may be estimated fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f33736d6d58511c255aea38ccae1953
https://doi.org/10.1101/2020.12.29.424744
https://doi.org/10.1101/2020.12.29.424744
Autor:
Ole Christian Lingjærde, Elen K. Höglander, Therese Sørlie, Christian Fougner, Tonje Lien, Silje Nord
Cancer transcriptomes are shaped by genetic and epigenetic features, such as DNA methylation and copy number aberrations. Knowledge of the relationships between gene expression and such features is fundamental to understanding the basis of tumor phen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efafbea815542da29208aa871087a3af
Autor:
Therese Sørlie, Arnoldo Frigessi, David M. Swanson, Jörg Tost, Tonje Lien, Fredrik Wärnberg, Helga Bergholtz, Maria Grazia Daidone
Publikováno v:
NPJ Breast Cancer
npj Breast Cancer, Vol 6, Iss 1, Pp 1-9 (2020)
npj Breast Cancer, Vol 6, Iss 1, Pp 1-9 (2020)
Ductal carcinoma in situ (DCIS) is a non-invasive type of breast cancer with highly variable potential of becoming invasive and affecting mortality. Currently, many patients with DCIS are overtreated due to the lack of specific biomarkers that distin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eebffcec9eddba20663378c5444e0bbc
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-418783
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-418783