Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Toni-Ann Mistretta"'
Autor:
Kjersti Aagaard, Kevin Riehle, Jun Ma, Nicola Segata, Toni-Ann Mistretta, Cristian Coarfa, Sabeen Raza, Sean Rosenbaum, Ignatia Van den Veyver, Aleksandar Milosavljevic, Dirk Gevers, Curtis Huttenhower, Joseph Petrosino, James Versalovic
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e36466 (2012)
While current major national research efforts (i.e., the NIH Human Microbiome Project) will enable comprehensive metagenomic characterization of the adult human microbiota, how and when these diverse microbial communities take up residence in the hos
Externí odkaz:
https://doaj.org/article/b94e8c9a56314b25b6bd009a5c0197cb
Autor:
Delphine M Saulnier, Filipe Santos, Stefan Roos, Toni-Ann Mistretta, Jennifer K Spinler, Douwe Molenaar, Bas Teusink, James Versalovic
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18783 (2011)
The genomes of four Lactobacillus reuteri strains isolated from human breast milk and the gastrointestinal tract have been recently sequenced as part of the Human Microbiome Project. Preliminary genome comparisons suggested that these strains belong
Externí odkaz:
https://doaj.org/article/3142b664e8894a7d9f9868582f071b47
Leveraging Human Microbiome Features to Diagnose and Stratify Children with Irritable Bowel Syndrome
Autor:
Bruno P. Chumpitazi, Julia L. Cope, Robert J. Shulman, Emily B. Hollister, Margaret M. Heitkemper, Richard A. Gibbs, Joseph F. Petrosino, Tor C. Savidge, James Versalovic, Sabeen Raza, Michelle Rubio-Gonzales, Mahmoud Dahdouli, Ginger A. Metcalf, Ruth Ann Luna, Erica M. Weidler, Donna M. Muzny, Numan Oezguen, Toni-Ann Mistretta
Publikováno v:
The Journal of Molecular Diagnostics : JMD
Accurate diagnosis and stratification of children with irritable bowel syndrome (IBS) remain challenging. Given the central role of recurrent abdominal pain in IBS, we evaluated the relationships of pediatric IBS and abdominal pain with intestinal mi
Autor:
Toni-Ann Mistretta, Michael R. Green, Leyuan Ma, Andrew Lewis, H. Daniel Lacorazza, Koramit Suppipat, Ye Shen, Paul Pang, Julie A. Tomolonis, Taylor J Chen, Monica Puppi, Chun Shik Park, Cory Seth Bridges, Rachel E. Rau
Publikováno v:
Blood. 134(22)
Leukemia stem cells are a rare population with a primitive progenitor phenotype that can initiate, sustain, and recapitulate leukemia through a poorly understood mechanism of self-renewal. Here, we report that Kruppel-like factor 4 (KLF4) promotes di
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 305:G74-G83
SOX9 regulates cell lineage specification by directly regulating target genes in a discrete number of tissues, and previous reports have shown cell proliferative and suppressive roles for SOX9. Although SOX9 is expressed in colorectal cancer, only a
Autor:
Kevin Y. Lee, Francesco J. DeMayo, Lauren Becnel, Yolanda F. Darlington, David Steffen, Apollo McOwiti, Toni-Ann Mistretta, Heather L. Franco, Jae Wook Jeong, Edward S. Chen
Publikováno v:
Molecular Endocrinology. 27:548-554
In order to understand the biology of the endometrium and potentially develop new diagnostic tools and treatments for endometrial diseases, the highly orchestrated gene expression/regulation that occurs within the uterus must first be understood. Eve
Autor:
Toni Ann Mistretta, Oliver A. Hampton, Pavel Sumazin, Patrick A. Thompson, Gail E. Tomlinson, Barry Zorman, Yi Chen, Rebecka L. Meyers, Dolores Lopez-Terrada, Murali Chintagumpala, Andras Heczey, David A. Wheeler, Kayuri U. Patel, Lisa R. Trevino, Sarah A. Comerford, D. Williams Parsons, Stephen F. Sarabia, Milton J. Finegold, Dinesh Rakheja
Publikováno v:
Hepatology (Baltimore, Md.). 65(1)
Despite being the most common liver cancer in children, hepatoblastoma (HB) is a rare neoplasm. Consequently, few pretreatment tumors have been molecularly profiled, and there are no validated prognostic or therapeutic biomarkers for HB patients. We
Autor:
Nathanael S. Gray, Toni Ann Mistretta, Karin R. Rabin, Monica Puppi, Terzah M. Horton, Chun Shik Park, Ye Shen, Koramit Suppipat, Jules P.P. Meijerink, H. D. Lacorazza
Publikováno v:
Leukemia, 31(6), 1314-1324. Nature Publishing Group
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy with a high incidence of relapse in pediatric ALL. Although most T-ALL patients exhibit activating mutations in NOTCH1, the cooperating genetic events required to a
Autor:
Angela Major, Margaret E. Conner, Delphine M. Saulnier, Sarah E. Blutt, Geoffrey A. Preidis, James Versalovic, Joseph F. Petrosino, Toni-Ann Mistretta, Kevin Riehle, Susan Venable, Milton J. Finegold
Publikováno v:
The FASEB Journal. 26:1960-1969
Beneficial microbes and probiotics show promise for the treatment of pediatric gastrointestinal diseases. However, basic mechanisms of probiosis are not well understood, and most investigations have been performed in germ-free or microbiome-depleted
Autor:
Michael R. Green, Rachel E. Rau, Ye Shen, Chun Shik Park, Daniel Lacorazza, Toni-Ann Mistretta, Andrew Lewis, Monica Puppi, Taylor Chen, Koramit Suppipat, Julie A. Tomolonis, Leyuan Ma, Paul Pang
Publikováno v:
Cancer Research. 78:145-145
Leukemia stem cells (LSCs) are a rare population able to sustain and recapitulate leukemia through a poorly understood mechanism of self-renewal. Because more than half of patients relapse after the cessation of TKI therapy, it is clear that a cure i