Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Toni Todorovski"'
Autor:
Federica Nicolini, Toni Todorovski, Eduard Puig, Mireia Díaz-Lobo, Marta Vilaseca, Jesús García, David Andreu, Ernest Giralt
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 6, Pp 4985-5004 (2023)
Tumour suppressor p53 plays a key role in the development of cancer and has therefore been widely studied in recent decades. While it is well known that p53 is biologically active as a tetramer, the tetramerisation mechanism is still not completely u
Externí odkaz:
https://doaj.org/article/f44ed63b83854cd8b170cb02e58d2cf5
Publikováno v:
Pharmaceutics, Vol 15, Iss 10, p 2451 (2023)
In recent decades, bioactive peptides have been gaining recognition in various biomedical areas, such as intracellular drug delivery (cell-penetrating peptides, CPPs) or anti-infective action (antimicrobial peptides, AMPs), closely associated to thei
Externí odkaz:
https://doaj.org/article/eabc3cc9f7874b4f9a6191fc0c6f69ca
Autor:
Álvaro Rol, Toni Todorovski, Pau Martin-Malpartida, Anna Escolà, Elena Gonzalez-Rey, Eric Aragón, Xavier Verdaguer, Mariona Vallès-Miret, Josep Farrera-Sinfreu, Eduard Puig, Jimena Fernández-Carneado, Berta Ponsati, Mario Delgado, Antoni Riera, Maria J. Macias
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Inflammatory bowel disease is caused by chronic inflammation of the gastrointestinal tract and disturbed immune responses. Here the authors present examination of Cortistatin analogues that display enhanced half-life stability whilst maintaining immu
Externí odkaz:
https://doaj.org/article/538094955b874388ace1e053acd30f22
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 357 (2023)
Infectious diseases caused by microbial pathogens (bacteria, virus, fungi, parasites) claim millions of deaths per year worldwide and have become a serious challenge to global human health in our century. Viral infections are particularly notable in
Externí odkaz:
https://doaj.org/article/87af4a732eaa464088dda77f1507a72b
Publikováno v:
Journal of Cheminformatics, Vol 11, Iss 1, Pp 1-15 (2019)
Abstract Random peptide libraries that cover large search spaces are often used for the discovery of new binders, even when the target is unknown. To ensure an accurate population representation, there is a tendency to use large libraries. However, p
Externí odkaz:
https://doaj.org/article/e1ec32859af54e12be8c9925e7586cab
Autor:
Toni Todorovski, Diogo A. Mendonça, Lorena O. Fernandes-Siqueira, Christine Cruz-Oliveira, Giuseppina Guida, Javier Valle, Marco Cavaco, Fernanda I. V. Limas, Vera Neves, Íris Cadima-Couto, Sira Defaus, Ana Salomé Veiga, Andrea T. Da Poian, Miguel A. R. B. Castanho, David Andreu
Publikováno v:
Pharmaceutics, Vol 14, Iss 4, p 738 (2022)
Viral disease outbreaks affect hundreds of millions of people worldwide and remain a serious threat to global health. The current SARS-CoV-2 pandemic and other recent geographically- confined viral outbreaks (severe acute respiratory syndrome (SARS),
Externí odkaz:
https://doaj.org/article/46403fb48abc4fbfb97dc626963881ce
Autor:
Giralt, Federica Nicolini, Toni Todorovski, Eduard Puig, Mireia Díaz-Lobo, Marta Vilaseca, Jesús García, David Andreu, Ernest
Publikováno v:
Current Issues in Molecular Biology; Volume 45; Issue 6; Pages: 4985-5004
Tumour suppressor p53 plays a key role in the development of cancer and has therefore been widely studied in recent decades. While it is well known that p53 is biologically active as a tetramer, the tetramerisation mechanism is still not completely u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::dde6a7647d55f2f43cff5b1abcf1b2fb
Publikováno v:
Pharmaceutics. 15:357
Infectious diseases caused by microbial pathogens (bacteria, virus, fungi, parasites) claim millions of deaths per year worldwide and have become a serious challenge to global human health in our century. Viral infections are particularly notable in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82d49d763073124ebe7dc3e2fc54cbb2
https://doi.org/10.3390/pharmaceutics15020357
https://doi.org/10.3390/pharmaceutics15020357
Autor:
Iris Cadima-Couto, María Angeles Jiménez, Marco Cavaco, Miguel A. R. B. Castanho, Diogo A. Mendonça, Ana Salomé Veiga, David Andreu, Vera Neves, Mariët Bakker, Christine Cruz-Oliveira, Sira Defaus, Toni Todorovski
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Bioconjugate Chemistry
instname
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Bioconjugate Chemistry
Passing through the blood-brain barrier (BBB) to treat neurological conditions is one of the main hurdles in modern medicine. Many drugs with promising in vitro profiles become ineffective in vivo due to BBB restrictive permeability. In particular, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652c31aa0ea10806204f2c4461837377
http://hdl.handle.net/10261/242950
http://hdl.handle.net/10261/242950
Autor:
David Andreu, Sandrine Sagan, Ana Salomé Veiga, Marco M. Domingues, Iris Cadima-Couto, Astrid Walrant, Toni Todorovski, Françoise Illien, Tiago N. Figueira, Miguel A. R. B. Castanho
Publikováno v:
ACS infectious diseases. 6(2)
© 2019 American Chemical Society
We have developed a nanocarrier consisting of large unilamellar vesicles (LUVs) for combined delivery of two human immunodeficiency virus type 1 (HIV-1) entry inhibitors, enfuvirtide (ENF) and protoporphyrin IX
We have developed a nanocarrier consisting of large unilamellar vesicles (LUVs) for combined delivery of two human immunodeficiency virus type 1 (HIV-1) entry inhibitors, enfuvirtide (ENF) and protoporphyrin IX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80ddbc354222e715c9d406a54fb42b12
https://pubmed.ncbi.nlm.nih.gov/31855415
https://pubmed.ncbi.nlm.nih.gov/31855415