Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Toni Rose Jue"'
Autor:
Ensieh M. Poursani, Daniele Mercatelli, Prahlad Raninga, Jessica L. Bell, Federica Saletta, Felix V. Kohane, Daniel P. Neumann, Ye Zheng, Jourdin R. C. Rouaen, Toni Rose Jue, Filip T. Michniewicz, Piper Schadel, Erin Kasiou, Maria Tsoli, Giuseppe Cirillo, Shafagh Waters, Tyler Shai-Hee, Riccardo Cazzoli, Merryn Brettle, Iveta Slapetova, Maria Kasherman, Renee Whan, Fernando Souza-Fonseca-Guimaraes, Linda Vahdat, David Ziegler, John G. Lock, Federico M. Giorgi, KumKum Khanna, Orazio Vittorio
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Background Metastatic cancer cells exploit Epithelial-mesenchymal-transition (EMT) to enhance their migration, invasion, and resistance to treatments. Recent studies highlight that elevated levels of copper are implicated in cancer progressi
Externí odkaz:
https://doaj.org/article/b17391f9a29d4891bcdc6914896812f8
Publikováno v:
BJUI Compass, Vol 4, Iss 1, Pp 44-58 (2023)
Abstract Metformin, the first line pharmacotherapy for type 2 diabetes has demonstrated favourable effects in prostate cancer (PCa) across a range of studies evaluating PCa patient outcomes amongst metformin users. However, a lack of rigorously condu
Externí odkaz:
https://doaj.org/article/ccdae71a614a4894ba3071199788d712
Publikováno v:
Trends in Cell Biology. 33:443-445
Autor:
John E. Pimanda, Bryan W. Day, Kerrie L. McDonald, Ashwin Unnikrishnan, Han Shen, Govardhan Anande, Shruthi Subramanian, Zeenat Jahan, Toni Rose Jue, Kathleen S. Ensbey, Sylvia A. Chung, Brett W. Stringer, Julie A.I. Thoms, Anchit Khanna
Figure S1, related to Figure 1: Expression and correlation of CHK1 and CIP2A in multiple glioma cohorts. Figure S2, related to Figure 1: Overall survival and mRNA expression of PP2A subunits in glioma patients. Figure S3, related to Figure 1: Role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::797ba9f3cc2355aafc11bcb0f6c2b6c1
https://doi.org/10.1158/1541-7786.22515163.v1
https://doi.org/10.1158/1541-7786.22515163.v1
Publikováno v:
BJUI compass. 4(1)
Metformin, the first line pharmacotherapy for type 2 diabetes has demonstrated favourable effects in prostate cancer (PCa) across a range of studies evaluating PCa patient outcomes amongst metformin users. However, a lack of rigorously conducted pros
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Glioblastoma (GBM) is a malignant brain tumour with a dismal prognosis, despite best treatment by surgical resection, radiation therapy (RT) and chemotherapy with temozolomide (TMZ). Nanoparticle (NP) therapy is an emerging consideration due to the a
Publikováno v:
Clinical Neurology and Neurosurgery. 164:75-80
The role of prognostic factors in the management of glioblastoma (GBM) is very important given the stasis in improving its clinical outcomes. Patients who initially present with a positive seizure history at diagnosis have anecdotally experienced sup
Autor:
Shruthi Subramanian, Zeenat Jahan, Toni Rose Jue, Anchit Khanna, Kerrie L. McDonald, Han Shen, Ashwin Unnikrishnan, Brett W. Stringer, Sylvia A. Chung, John E. Pimanda, Govardhan Anande, Bryan W. Day, Kathleen S. Ensbey, Julie A. I. Thoms
Publikováno v:
Molecular cancer research : MCR. 18(5)
High-constitutive activity of the DNA damage response protein checkpoint kinase 1 (CHK1) has been shown in glioblastoma (GBM) cell lines and in tissue sections. However, whether constitutive activation and overexpression of CHK1 in GBM plays a functi
Autor:
Shane Whittaker, Kerrie L. McDonald, Sylvia A. Chung, Elizabeth Hovey, Victor M. Lu, Julia Yin, Toni Rose Jue, Anna H. Siddell, Jacob Fairhall, Robert W. Rapkins
Glioblastoma (GBM), a malignant brain tumour that occur in adults and children, represents a major challenge for treatment. Tumor heterogeneity has been shown to contribute to this problem. The aim of this study was to overcome this issue by explorin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e16cc91bfe6b287892e5c28b2a4f4cf
https://europepmc.org/articles/PMC6216450/
https://europepmc.org/articles/PMC6216450/
Autor:
Toni Rose, Jue, Lauren R, Olafson, Anna H, Siddell, Robert W, Rapkins, Benedict, Ng, Julia X M, Yin, Victor M, Lu, Sylvia A, Chung, Shane P, Whittaker, Matthew, Davies, Jacob M, Fairhall, Elizabeth J, Hovey, Kerrie L, McDonald
Publikováno v:
Cold Spring Harbor Molecular Case Studies
Effective treatments that extend survival of malignant brain tumor glioblastoma (GBM) have not changed in more than a decade; however, there exists a minority patient group (