Výsledky vyhledávání - "Toni M. Hopkins"

Nicotine activates cell-signaling pathways through muscle-type and neuronal nicotinic acetylcholine receptors in non-small cell lung cancer cells

Autor: Jill M. Siegfried, Diane L. Carlisle, Xuwan Liu, Toni M. Hopkins, Michelle C. Swick, Rajiv Dhir

Publikováno v: Pulmonary Pharmacology & Therapeutics. 20:629-641

Nicotinic acetylcholine receptors (nAChR) are expressed on non-neuronal cell types, including normal bronchial epithelial cells, and nicotine has been reported to cause Akt activation in cultured normal airway cells. This study documents mRNA and pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87b536cf76ecee4c3be1da5315422b22
https://doi.org/10.1016/j.pupt.2006.07.001

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The Influence of Arm Length Asymmetry and Base Substitution on the Activity of the 10-23 DNA Enzyme

Autor: Murray J. Cairns, Toni M. Hopkins, Craig Witherington, Lun-Quan Sun

Publikováno v: Antisense and Nucleic Acid Drug Development. 10:323-332

A small oligodeoxyribonucleotide derived from in vitro selection has been shown to be capable of efficient sequence-specific cleavage of RNA at purine-pyrimidine junctions. As the reaction readily takes place under simulated physiologic conditions, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd13b5d2971cc6da2154834b71679886
https://doi.org/10.1089/oli.1.2000.10.323

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Human non-small cell lung tumors and cells derived from normal lung express both estrogen receptor alpha and beta and show biological responses to estrogen

Autor: Laura P, Stabile, Autumn L Gaither, Davis, Christopher T, Gubish, Toni M, Hopkins, James D, Luketich, Neil, Christie, Sydney, Finkelstein, Jill M, Siegfried

Publikováno v: Cancer research. 62(7)

Lung cancer is becoming increasingly common in women and in the United States accounts for more female cancer deaths annually than breast cancer. Many epidemiological studies have provided evidence that women are more susceptible than men to the adve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a8fe5be6297ac82ddb8063c9d91002fd
https://pubmed.ncbi.nlm.nih.gov/11929836

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Target site selection for an RNA-cleaving catalytic DNA

Autor: Murray J. Cairns, Craig Witherington, Lun-Quan Sun, Toni M. Hopkins, Li Wang

Publikováno v: Nature biotechnology. 17(5)

A small catalytic DNA, known as the 10–23 DNA enzyme or deoxyribozyme, has been shown to efficiently hydrolyze RNA at purine-pyrimidine (R-Y) junctions in vitro. Although these potentially cleavable junctions are ubiquitous, they are often protecte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f85500747bb4a4d8166e61b1a9fb4344
https://pubmed.ncbi.nlm.nih.gov/10331790

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