Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Toni L Williamson"'
Autor:
M Ann Mongan, Robert T Dunn, Steven Vonderfecht, Nancy Everds, Guang Chen, Cheng Su, Marnie Higgins-Garn, Yuan Chen, Cynthia A Afshari, Toni L Williamson, Linda Carlock, Christopher Dipalma, Suzanne Moss, Jeanine Bussiere, Charles Qualls, Yudong D He, Hisham K Hamadeh
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15595 (2010)
Genome-wide gene expression profiling has become standard for assessing potential liabilities as well as for elucidating mechanisms of toxicity of drug candidates under development. Analysis of microarray data is often challenging due to the lack of
Externí odkaz:
https://doaj.org/article/6f64d4f7790f4d45ad6e4ed7980b8a19
Autor:
Toni L. Williamson, Don W. Cleveland
Publikováno v:
Nature Neuroscience. 2:50-56
Mutations in copper/zinc superoxide dismutase 1 (SOD1), primary causes of human amyotrophic lateral sclerosis (ALS), provoke motor neuron death through an unidentified toxic property. The known neurofilament-dependent slowing of axonal transport, com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e85e51139aef5a0965c3dda60de9d1
https://doi.org/10.1038/4553
https://doi.org/10.1038/4553
Autor:
Toni L. Williamson, Lucie Bruijn, Robert H. Brown, Janet D. Vechio, Joseph R. Marszalek, Zuoshang Xu, Michael K. Lee, Don W. Cleveland
Publikováno v:
Cold Spring Harbor Symposia on Quantitative Biology. 61:709-723
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68ed6c9f3bff6e40ba14e898b1221d0f
https://doi.org/10.1101/sqb.1996.061.01.071
https://doi.org/10.1101/sqb.1996.061.01.071
Autor:
Thomas O. Crawford, Joseph R. Marszalek, Zuoshang Xu, Paul N. Hoffman, Mark W. Becher, Toni L. Williamson, Don W. Cleveland, Michael K. Lee
Publikováno v:
The Journal of Cell Biology
To examine the mechanism through which neurofilaments regulate the caliber of myelinated axons and to test how aberrant accumulations of neurofilaments cause motor neuron disease, mice have been constructed that express wild-type mouse NF-H up to 4.5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64499d99dee5f62d7947bb0a619073ba
http://europepmc.org/articles/PMC2121055
http://europepmc.org/articles/PMC2121055
Autor:
Jonathan D, Best, Mark T, Jay, Franklin, Otu, Jerome, Ma, Alan, Nadin, Semantha, Ellis, Huw D, Lewis, Christine, Pattison, Michael, Reilly, Timothy, Harrison, Mark S, Shearman, Toni L, Williamson, John R, Atack
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 313(2)
The efficacy of gamma-secretase inhibitors in vivo has, to date, been generally assessed in transgenic mouse models expressing increased levels of amyloid-beta (Abeta) peptide thereby allowing the detection of changes in Abeta production. However, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::11a549defd85d15e582ed5a7e9861c4c
https://pubmed.ncbi.nlm.nih.gov/15743924
https://pubmed.ncbi.nlm.nih.gov/15743924
Autor:
Jean-Pierre Julien, Lucie Bruijn, Qinzhang Zhu, Scott D. Anderson, Toni L. Williamson, Don W. Cleveland, Karen L. Anderson
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 95(16)
Mutations in superoxide dismutase 1 (SOD1), the only proven cause of amyotrophic lateral sclerosis (ALS), provoke disease through an unidentified toxic property. Neurofilament aggregates are pathologic hallmarks of both sporadic and SOD1-mediated fam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a6f33243a235c41f018a2294a10454
https://pubmed.ncbi.nlm.nih.gov/9689132
https://pubmed.ncbi.nlm.nih.gov/9689132
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 93(26)
To examine the role of microtubules in growth cone turning, we have compared the microtubule organization in growth cones advancing on uniform laminin substrates with their organization in growth cones turning at a laminin–tenascin border. The majo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e02f57373d4154bceb6e6c042cb5e93
https://pubmed.ncbi.nlm.nih.gov/8986791
https://pubmed.ncbi.nlm.nih.gov/8986791
Autor:
Ross Hawkes, Phillip R. Gordon-Weeks, James W. Gurd, Toni L. Williamson, Philip W. Beesley, A Can, Timothy Willmott, Rosemary S. Mummery
Publikováno v:
Neuroscience. 58(1)
The monoclonal antibody PAC 1 (postsynaptic density and cytoskeleton enriched) recognizes an epitope present on two postsynaptic density-enriched glycoproteins of 130,000 (postsynaptic densityenriched glycoprotein 130) and 117,000 mol. wt (postsynapt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb780bf34964c04af1ba539712d5faaf
https://pubmed.ncbi.nlm.nih.gov/7512700
https://pubmed.ncbi.nlm.nih.gov/7512700
Autor:
Jian Liu, Don W. Cleveland, Laura Corson, Lan Huang, Al Burlingame, Toni L. Williamson, Lucie Bruijn
Publikováno v:
Science. 288:399-399
Estevez et al . ([1][1]) focused on a potential mechanism through which dominantly inherited mutation in superoxide dismutase 1 (SOD1), an abundant, ubiquitously expressed antioxidant protein, triggers the selective death of motor neurons in amyotrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d83bddda1a55a0292f1e7178d544c7da
https://doi.org/10.1126/science.288.5465.399a
https://doi.org/10.1126/science.288.5465.399a
Publikováno v:
Biochemical Society Transactions. 20:154S-154S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b37ba29209cb642564ad2445fe5c8fc
https://doi.org/10.1042/bst020154s
https://doi.org/10.1042/bst020154s