Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Toni Cheung"'
Autor:
Louise Dickson, Martin Teall, Elodie Chevalier, Toni Cheung, Gemma M. Liwicki, Stephen Mack, Anne Stephenson, Kathryn White, Richard Fosbeary, David C. Harrison, Nicola L. Brice, Kevin Doyle, Roberto Ciccocioppo, Chaobo Wu, Sarah Almond, Toshal R. Patel, Philip Mitchell, Matt Barnes, Andrew P. Ayscough, Lee A. Dawson, Mark Carlton, Roland W. Bürli
Publikováno v:
ACS Medicinal Chemistry Letters. 14:442-449
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b699dbaa54447db5440fdb155aa05eb4
https://doi.org/10.1021/acsmedchemlett.2c00529
https://doi.org/10.1021/acsmedchemlett.2c00529
Autor:
Bernardino Ossola, Ali Rifat, Anna Rowland, Helen Hunter, Samuel Drinkall, Clare Bender, Mayida Hamlischer, Martin Teall, Russell Burley, Daneil F. Barker, David Cadwalladr, Louise Dickson, Jason M.K. Lawrence, Jenna R.M. Harvey, Marina Lizio, Xiao Xu, Edel Kavanagh, Toni Cheung, Steve Sheardown, Catherine B. Lawrence, Michael Harte, David Brough, Christian Madry, Kim Matthews, Kevin Doyle, Keith Page, Justin Powell, Nicola L. Brice, Roland W. Bürli, Mark B. Carlton, Lee A. Dawson
Publikováno v:
Neuropharmacology. 224
Neuroinflammation, specifically the NLRP3 inflammasome cascade, is a common underlying pathological feature of many neurodegenerative diseases. Evidence suggests that NLRP3 activation involves changes in intracellular K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28dc2da491de466f3d474771aad12f3b
https://pubmed.ncbi.nlm.nih.gov/36375694
https://pubmed.ncbi.nlm.nih.gov/36375694
Autor:
Russell Burley, Richard C. Hewer, Martin Teall, Louise Dickson, Bernardino Ossola, Sam Russell, Clare Bender, Toni Cheung, Justin A.C. Powell, Xiao Xu, Nicola L. Brice, Lucy Otter, Marta Arimont, Sarah L. Kidd, David Vidal, James W. Dale, Lewis Mervin, Hannah F. Sore, Natalia Mateu, Narayana Lakshminarayana, Lee A. Dawson, Mark Carlton, Roland W. Bürli
Publikováno v:
Bioorganicmedicinal chemistry letters. 61
We report a significant decrease in transcription of the G protein-coupled receptor GPR39 in striatal neurons of Parkinson's disease patients compared to healthy controls, suggesting that a positive modulator of GPR39 may beneficially impact neuropro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ad575538566fdb73049d116f134aff
https://pubmed.ncbi.nlm.nih.gov/35123006
https://pubmed.ncbi.nlm.nih.gov/35123006
Autor:
Victoria J Mulligan, Toni Cheung, Joseph Russo, Nidhi Kaushal, Nicola Brice, Louise Dickson, Darian Bartkowski, Steven A. Sheardown, Lee A. Dawson, Justin Powell, J Russell Burley, Stephen H Hitchcock, Natalie Hosea, Mark Carlton, Hans H Schiffer, Huikai Sun, Yun Chen, Jason Lawrence, Holger Monenschein, Murphy Sean, Anne Kanta, Xiao Xu, Keith Page
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 377(3)
GPR6 is an orphan G-protein–coupled receptor that has enriched expression in the striatopallidal, indirect pathway and medium spiny neurons of the striatum. This pathway is greatly impacted by the loss of the nigro-striatal dopaminergic neurons in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7699037aeac8e0d7d1449554af6add50
https://pubmed.ncbi.nlm.nih.gov/33795395
https://pubmed.ncbi.nlm.nih.gov/33795395
Autor:
William Farnaby, Louise Dickson, Stephen Robert Mack, William J. Buffham, Daniel Brown, Jonathan Ellery, Philip J. Mitchell, Matt Barnes, Loredana Ciuclan, Richard J. Isaacs, Toni Cheung, Peter Bunyard
Publikováno v:
European Journal of Pharmacology. 833:8-15
The Lysophosphatidic Acid 1 Receptor (LPA1 receptor) has been linked to the initiation and progression of a variety of poorly treated fibrotic conditions. Several compounds that have been described as LPA1 receptor antagonists have progressed into cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e5742ec80a1e381fa6dfced5b86bf14
https://doi.org/10.1016/j.ejphar.2018.05.040
https://doi.org/10.1016/j.ejphar.2018.05.040
Autor:
Jonathan, Ellery, Louise, Dickson, Toni, Cheung, Loredana, Ciuclan, Peter, Bunyard, Stephen, Mack, William J, Buffham, William, Farnaby, Philip, Mitchell, Daniel, Brown, Richard, Isaacs, Matt, Barnes
Publikováno v:
European journal of pharmacology. 833
The Lysophosphatidic Acid 1 Receptor (LPA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b208b89dc3cd73820c9a54c572f7c7b
https://pubmed.ncbi.nlm.nih.gov/29807028
https://pubmed.ncbi.nlm.nih.gov/29807028