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pro vyhledávání: '"Toni C. Wolinsky"'
Autor:
Lingyun Wu, Gamini Chandrasena, Vrej Jubian, Kai Lu, Toni C. Wolinsky, Mary W. Walker, Mathivanan Packiarajan
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(6)
A novel series of indolyl and dihydroindolyl glycinamides were identified as potent NPY5 antagonists with in vivo activity from screen hit 1. The dihydroindolyl glycinamide 10a significantly inhibits NPY5 agonist induced feeding at a dose of 0.1 mg/k