Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Tongzheng, Liu"'
Autor:
Yalei Wen, Hui Wang, Xiao Yang, Yingjie Zhu, Mei Li, Xiuqing Ma, Lei Huang, Rui Wan, Caishi Zhang, Shengrong Li, Hongling Jia, Qin Guo, Xiaoyun Lu, Zhengqiu Li, Xiangchun Shen, Qiushi Zhang, Lu Si, Chengqian Yin, Tongzheng Liu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Activating mutations in NRAS account for 15–20% of melanoma, yet effective anti-NRAS therapies are still lacking. In this study, we unveil the casein kinase 1δ (CK1δ) as an uncharacterized regulator of oncogenic NRAS mutations, specifica
Externí odkaz:
https://doaj.org/article/83e26542cf344856a8abf2d239e81390
Autor:
Jinfeng Ren, Tongzheng Liu, Luyan You, Minghui Hu, Jianping Zhu, Xinyu Wang, Hao Zhang, Jiayu Zhang, Zifa Li, Sheng Wei, Xiwen Geng
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e34082- (2024)
Parkinson's disease (PD) is a severe neurodegenerative disease that disturbs human health. In the laboratory researches about PD, the mice model induced by intraperitoneal injection of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) was widely us
Externí odkaz:
https://doaj.org/article/ae2f54e8bd0547928e1300deee5dfabf
Autor:
Xiaobo Li, Qi Qi, Yong Li, Qun Miao, Wenqian Yin, Jinghua Pan, Zhan Zhao, Xiaoying Chen, Fan Yang, Xiaofeng Zhou, Maohua Huang, Chenran Wang, Lijuan Deng, Dandan Huang, Ming Qi, Shuran Fan, Yiran Zhang, Shenghui Qiu, Weiqing Deng, Tongzheng Liu, Minfeng Chen, Wencai Ye, Dongmei Zhang
Publikováno v:
Advanced Science, Vol 10, Iss 30, Pp n/a-n/a (2023)
Abstract Hematogenous metastasis is the main approach for colorectal cancer liver metastasis (CRCLM). However, as the gatekeepers in the tumor vessels, the role of TPCs in hematogenous metastasis remains largely unknown, which may be attributed to th
Externí odkaz:
https://doaj.org/article/68f0ffc940434dbeb111b958fe03663f
Autor:
Hongling Jia, Hui Wang, Lan Cao, Zhisheng Lai, Zichun Cheng, Qingpei Chen, Tongzheng Liu, Xiangyi Liu, Yanting Wen, Conghui Xu, Weizhi Lu, Guang Yang, Deqian Zhou, Biao Di, Feng Gao, Zhicong Yang
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 306-309 (2022)
Since the SARS-CoV-2 Omicron variant was first reported from South Africa, it has rapidly spread in over 100 countries. Only two cases infected by the Omicron variant were recently identified in China. The one case in Guangzhou has a relatively long
Externí odkaz:
https://doaj.org/article/13808d057e6f4d718381b61b7d5d16a2
Autor:
Tangming Guan, Mei Li, Yan Song, Jiayi Chen, Jiaxin Tang, Caishi Zhang, Yalei Wen, Xiao Yang, Lei Huang, Yingjie Zhu, Hongxian Wang, Ke Ding, Junxia Zheng, Haoxing Zhang, Tongzheng Liu
Publikováno v:
Advanced Science, Vol 10, Iss 11, Pp n/a-n/a (2023)
Abstract Triple‐negative breast cancer (TNBC) is a highly lethal malignancy with limited therapy options. TWIST1, a key transcriptional factor of epithelial‐mesenchymal transition (EMT), contributes to self‐renewal of cancer stem‐like cells (
Externí odkaz:
https://doaj.org/article/2378de3cdb6043609a9dc6116b174f43
Autor:
Yanping Wu, Xiang Luo, Qingqing Zhou, Haibiao Gong, Huaying Gao, Tongzheng Liu, Jiaxu Chen, Lei Liang, Hiroshi Kurihara, Yi-Fang Li, Rong-Rong He
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 197-209 (2022)
The relationship between chronic psychological stress and tumorigenesis has been well defined in epidemiological studies; however, the underlying mechanism remains underexplored. In this study, we discovered that impaired macrophage phagocytosis cont
Externí odkaz:
https://doaj.org/article/5a3a8b13c9d44e788421c8c484cc3817
Autor:
Ming Qi, Shuran Fan, Maohua Huang, Jinghua Pan, Yong Li, Qun Miao, Wenyu Lyu, Xiaobo Li, Lijuan Deng, Shenghui Qiu, Tongzheng Liu, Weiqing Deng, Xiaodong Chu, Chang Jiang, Wenzhuo He, Liangping Xia, Yunlong Yang, Jian Hong, Qi Qi, Wenqian Yin, Xiangning Liu, Changzheng Shi, Minfeng Chen, Wencai Ye, Dongmei Zhang
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 3 (2023)
Externí odkaz:
https://doaj.org/article/27620c554ac14c62ab1e0555e2a19330
Autor:
Yalei Wen, Yingjie Zhu, Caishi Zhang, Xiao Yang, Yuchen Gao, Mei Li, Hongyan Yang, Tongzheng Liu, Hui Tang
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Chronic inflammation plays a pivotal role in cancer development. Cancer cells interact with adjacent cellular components (pro-inflammatory cells, intrinsic immune cells, stromal cells, etc.) and non-cellular components to form the inflammatory tumor
Externí odkaz:
https://doaj.org/article/65947701593845719c697c8283a19479
Autor:
Tingting Shi, Jun Bai, Diyuan Yang, Li Huang, Hui-Feng Fan, Dong-Wei Zhang, Tongzheng Liu, Gen Lu
Publikováno v:
Heliyon, Vol 8, Iss 10, Pp e10807- (2022)
Introduction: Worldwide, Human adenoviruses (ADV) cause a significant portion of childhood mortality. The severity of ADV Community-acquired Pneumonia (CAP) can be assessed by clinical features, but the rapid and accurate diagnostic biomarkers are st
Externí odkaz:
https://doaj.org/article/ec6aaee03a204e478e29dcdb17798d06
Autor:
Changrong Lai, Jiayi Chen, Jing Liu, Danmei Tian, Donghe Lan, Tongzheng Liu, Bin Wu, Hongkai Bi, Jinshan Tang
Publikováno v:
Marine Drugs, Vol 20, Iss 11, p 720 (2022)
Marine fungi-derived secondary metabolites are still an important source for the discovery of potential antimicrobial agents. Here, five new polyketides (1, 2, and 6–8) and seven known compounds (3–5 and 9–12) were obtained from the culture of
Externí odkaz:
https://doaj.org/article/f1a975c37e4b4f8d9031d185beab2e4d