Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Tongyu Rui"'
Publikováno v:
Molecular Neurobiology. 59:3124-3139
Numerous studies have demonstrated the role of neuroinflammation in mediating acute pathophysiological events of early brain injury after subarachnoid hemorrhage (SAH). However, it is not clear how to target this inflammatory cascade after SAH. M1 ac
Autor:
Ying Cheng, Yuan Gao, Jing Li, Tongyu Rui, Qianqian Li, Huan Chen, Bowen Jia, Yiting Song, Zhiya Gu, Tao Wang, Cheng Gao, Ying Wang, Zufeng Wang, Fudi Wang, Luyang Tao, Chengliang Luo
Publikováno v:
Free radical biologymedicine. 194
Ferroptosis is a form of regulated cell death that is mainly triggered by iron-dependent lipid peroxidation. A growing body of evidence suggests that ferroptosis is involved in the pathophysiology of traumatic brain injury (TBI), and tropomyosin-rela
Autor:
Ying Cheng, Wenhao Qu, Jing Li, Bowen Jia, Yiting Song, Liyu Wang, Tongyu Rui, Qianqian Li, Chengliang Luo
Publikováno v:
ACS chemical neuroscience. 13(5)
As a specific ferroptosis marker, transferrin receptor 1 (TfR1) expression is increased following traumatic brain injury (TBI), but the precise role of TfR1 in TBI-induced ferroptosis and neurodegeneration remains to be determined. To further identif
Early inflammation is a significant factor in acute pathophysiological events of early brain injury (EBI) after subarachnoid hemorrhage (SAH). Although there have been numerous studies of neuroinflammation and SAH, the effect of M1 microglia on the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e6dfbb80ca1d47f4b5bdc3049cee89d
https://doi.org/10.21203/rs.3.rs-856199/v1
https://doi.org/10.21203/rs.3.rs-856199/v1
Autor:
Cheng Gao, Yan-Yan Fan, Xiping Chen, Jiaxin Zhang, Tongyu Rui, Yuan Gao, Luyang Tao, Hengji Shen, Chengliang Luo, Xueshi Chen, Y Yao, Dongya Li, Zufeng Wang, Haochen Wang, Mingyang Zhang, Tao Wang, Chongjian Xia, Li-li Li
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 35(10)
Autophagy is a self-phagocytic and highly evolutionarily conserved intracellular lysosomal catabolic system, which plays a vital role in a variety of trauma models, including skin wound healing (SWH). However, the roles and potential mechanisms of au
Autor:
Jie Chen, Ya’nan Yan, Luyang Tao, Mengyang Yan, Xiping Chen, Tongyu Rui, Li Hui, Haochen Wang, Qiufang Jia, Zhiqi Cheng, Zhiya Gu
Background: As an important signaling pathway during embryonic development, WNT/β-catenin signaling regulates cell proliferation and differentiation. However, the role of WNT pathway on central nervous system (CNS) injury is not clear. Methods: In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5bf58cb3b86885c2166f479138478dc
https://doi.org/10.21203/rs.3.rs-541915/v1
https://doi.org/10.21203/rs.3.rs-541915/v1
Autor:
Chengliang Luo, Xiping Chen, Ya’nan Yan, Cheng Gao, Tao Wang, Luyang Tao, Guang Chen, Tongyu Rui, Yuan Gao, Zhiqi Cheng, Xueshi Chen
Publikováno v:
Experimental neurology. 342
Traumatic brain injury (TBI) is a major cause of death and disability worldwide. Various forms of cells death are involved in the pathological process of TBI, without exception to ferroptosis, which is mainly triggered by iron-dependent lipid peroxid
Autor:
Yuan Gao, Zufeng Wang, Xuying Ma, Cheng Gao, Shunchen Song, Luyang Tao, Mingyang Zhang, Zhiya Gu, Junxia Min, Jian Zhang, Tao Wang, Xuexian Fang, Chengliang Luo, Chunling Wang, Guang Chen, Tongyu Rui, Ying Cheng, Haochen Wang, Xiping Chen, Qianqian Li, Fudi Wang
Publikováno v:
Journal of Pineal Research. 70
Accumulating evidence demonstrates that ferroptosis may be important in the pathophysiological process of traumatic brain injury (TBI). As a major hormone of the pineal gland, melatonin exerts many beneficial effects on TBI, but there is no informati
Publikováno v:
Histology and histopathology. 36(4)
Brain injury is accompanied by serious iron metabolism disorder and oxidative stress. As a novel form of regulated cell death (RCD) depending on lipid peroxidation caused by iron overload, ferroptosis (FPT) further aggravates brain injury, which is d
Publikováno v:
Experimental brain research. 239(5)
As a selective inhibitor of mitochondrial fission protein dynamin-related protein-1 (Drp1), mitochondrial division inhibitor 1 (mdivi-1) can cross the blood-brain barrier (BBB) and exert neuroprotection. However, it remains unclear whether mdivi-1 ca