Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Tongguan Tian"'
Autor:
Jing He, Mingen Lin, Xinchao Zhang, Ruonan Zhang, Tongguan Tian, Yuefan Zhou, Wenjing Dong, Yajing Yang, Xue Sun, Yue Dai, Yue Xu, Zhenru Zhang, Ming Xu, Qun-Ying Lei, Yanping Xu, Lei Lv
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-15 (2023)
Abstract Tumor development, involving both cell growth (mass accumulation) and cell proliferation, is a complex process governed by the interplay of multiple signaling pathways. TET2 mainly functions as a DNA dioxygenase, which modulates gene express
Externí odkaz:
https://doaj.org/article/f14e9dc959e64d9eb8fb2ae99ea97411
Autor:
Tongguan Tian, Xiao Xie, Wanwan Yi, Yuefan Zhou, Yixin Xu, Zhenxiang Wang, Junjing Zhang, Mingen Lin, Ruonan Zhang, Zhongwei Lv, Xinxing Li, Lei Lv, Yanping Xu
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113362- (2023)
Summary: Upregulation of FGL1 helps tumors escape from immune surveillance, and therapeutic antibodies targeting FGL1 have potential as another immune checkpoint inhibitor. However, the underlying mechanism of high FGL1 protein level in cancers is no
Externí odkaz:
https://doaj.org/article/8e874494170d46a084771dd379895838
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e16417- (2023)
With the progress of society, the health problems of pets have attracted more and more attention. Recent studies have shown that intestinal microflora and related fecal metabolites play a crucial role in the healthy growth of cats. However, the poten
Externí odkaz:
https://doaj.org/article/1a61d4cab5564ba0b22495bc8f3b9601
Autor:
Jing He, Mingen Lin, Xinchao Zhang, Ruonan Zhang, Tongguan Tian, Yuefan Zhou, Wenjing Dong, Yajing Yang, Xue Sun, Yue Dai, Yue Xu, Zhenru Zhang, Ming Xu, Qun-Ying Lei, Yanping Xu, Lei Lv
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/29dfc5f129eb43fcb2310ecd9839a26c
Autor:
Jing Shi, Xiang Gao, Tongguan Tian, Zhaoyang Yu, Bo Gao, Aijia Wen, Linlin You, Shenghai Chang, Xing Zhang, Yu Zhang, Yu Feng
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Bacteriophage Q protein serves as a model regulator for the study of transcription elongation. Here the authors report a cryo-EM structure of an intact Q-engaged arrested complex, revealing the interactions responsible for σ-dependent pause, Q engag
Externí odkaz:
https://doaj.org/article/7e9689354b724ad5a73fd6c510dd9e7b
Autor:
Yunjie Shi, Yunxiang Fang, Tongguan Tian, Weiping Chen, Qiang Sun, Fangqi Guo, Piqing Gong, Chunmei Li, Hao Wang, Zhiqian Hu, Xinxing Li
Background: We aimed to evaluate whether extracellular vesicles (EV)-derived microRNAs (miRNAs) can be used as biomarkers for advanced adenoma (AA) and colorectal cancer (CRC). Methods: We detected the changes in the plasma EV-delivered miRNA profile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d5e4ec667a40028039b68b4870eb86
https://doi.org/10.21203/rs.3.rs-2751954/v1
https://doi.org/10.21203/rs.3.rs-2751954/v1
Autor:
Lei Lv, Yanping Xu, Qing Zhang, Jing Zhang, Qun-Ying Lei, Yixin Xu, Yuefan Zhou, Tongguan Tian, Yajing Yang, Mingen Lin, Wenjing Dong, Ruonan Zhang, Yunjie Jin, Jing He, Shuyan Li, Xinchao Zhang
Inactivating mutations of von Hippel–Lindau (VHL) are highly prevalent in clear cell renal cell carcinoma (ccRCC). Improved understanding of the vulnerabilities of VHL-deficient ccRCC could lead to improved treatment strategies. The activity of DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b112e67ed321506f34e0283187154ec
https://doi.org/10.1158/0008-5472.c.6513850.v1
https://doi.org/10.1158/0008-5472.c.6513850.v1
Autor:
Lei Lv, Yanping Xu, Qing Zhang, Jing Zhang, Qun-Ying Lei, Yixin Xu, Yuefan Zhou, Tongguan Tian, Yajing Yang, Mingen Lin, Wenjing Dong, Ruonan Zhang, Yunjie Jin, Jing He, Shuyan Li, Xinchao Zhang
Supplementary Data from TET2 Suppresses VHL Deficiency-Driven Clear Cell Renal Cell Carcinoma by Inhibiting HIF Signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01284a985446bba48b3596090de54f56
https://doi.org/10.1158/0008-5472.22431241.v1
https://doi.org/10.1158/0008-5472.22431241.v1
Autor:
Ruonan Zhang, Yajing Yang, Wenjing Dong, Mingen Lin, Jing He, Xinchao Zhang, Tongguan Tian, Yunlong Yang, Kun Chen, Qun-Ying Lei, Song Zhang, Yanping Xu, Lei Lv
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Breast cancer is the most frequent malignancy in women worldwide, and triple-negative breast cancer (TNBC) patients have the worst prognosis and highest risk of recurrence. The therapeutic strategies for TNBC are limited. It is urgent to develop new
Autor:
Xinchao Zhang, Shuyan Li, Jing He, Yunjie Jin, Ruonan Zhang, Wenjing Dong, Mingen Lin, Yajing Yang, Tongguan Tian, Yuefan Zhou, Yixin Xu, Qun-Ying Lei, Jing Zhang, Qing Zhang, Yanping Xu, Lei Lv
Publikováno v:
Cancer research. 82(11)
Inactivating mutations of von Hippel–Lindau (VHL) are highly prevalent in clear cell renal cell carcinoma (ccRCC). Improved understanding of the vulnerabilities of VHL-deficient ccRCC could lead to improved treatment strategies. The activity of DNA