Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Tongcui, Ma"'
Autor:
Hannah S. Sperber, Kyle A. Raymond, Mohamed S. Bouzidi, Tongcui Ma, Silvana Valdebenito, Eliseo A. Eugenin, Nadia R. Roan, Steven G. Deeks, Sandra Winning, Joachim Fandrey, Roland Schwarzer, Satish K. Pillai
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113285- (2023)
Summary: Deciphering the mechanisms underlying viral persistence is critical to achieving a cure for human immunodeficiency virus (HIV) infection. Here, we implement a systems approach to discover molecular signatures of HIV latently infected CD4+ T
Externí odkaz:
https://doaj.org/article/567b96777f57431eaf3a3ff5e8e86150
Autor:
Tongcui Ma, Matthew McGregor, Leila Giron, Guorui Xie, Ashley F George, Mohamed Abdel-Mohsen, Nadia R Roan
Publikováno v:
eLife, Vol 11 (2022)
High-parameter single-cell phenotyping has enabled in-depth classification and interrogation of immune cells, but to date has not allowed for glycan characterization. Here, we develop CyTOF-Lec as an approach to simultaneously characterize many prote
Externí odkaz:
https://doaj.org/article/11ad9b2293b548ec8928b0045a349672
Autor:
Jason Neidleman, Xiaoyu Luo, Julie Frouard, Guorui Xie, Gurjot Gill, Ellen S. Stein, Matthew McGregor, Tongcui Ma, Ashley F. George, Astrid Kosters, Warner C. Greene, Joshua Vasquez, Eliver Ghosn, Sulggi Lee, Nadia R. Roan
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 6, Pp 100081- (2020)
Summary: Convalescing coronavirus disease 2019 (COVID-19) patients mount robust T cell responses against SARS-CoV-2, suggesting an important role of T cells in viral clearance. To date, the phenotypes of SARS-CoV-2-specific T cells remain poorly defi
Externí odkaz:
https://doaj.org/article/a72f1c6b4feb4f37be67cf2c5c77d4e5
Autor:
Jason Neidleman, Xiaoyu Luo, Julie Frouard, Guorui Xie, Feng Hsiao, Tongcui Ma, Vincent Morcilla, Ashley Lee, Sushama Telwatte, Reuben Thomas, Whitney Tamaki, Benjamin Wheeler, Rebecca Hoh, Ma Somsouk, Poonam Vohra, Jeffrey Milush, Katherine Sholtis James, Nancie M Archin, Peter W Hunt, Steven G Deeks, Steven A Yukl, Sarah Palmer, Warner C Greene, Nadia R Roan
Publikováno v:
eLife, Vol 9 (2020)
The latent reservoir is a major barrier to HIV cure. As latently infected cells cannot be phenotyped directly, the features of the in vivo reservoir have remained elusive. Here, we describe a method that leverages high-dimensional phenotyping using C
Externí odkaz:
https://doaj.org/article/498edfb6f058495dafa1f755ce519293
Autor:
Florent Colomb, Leila B. Giron, Leticia Kuri-Cervantes, Opeyemi S. Adeniji, Tongcui Ma, Harsh Dweep, Emilie Battivelli, Eric Verdin, Clovis S. Palmer, Hiroaki Tateno, Andrew V. Kossenkov, Nadia R. Roan, Michael R. Betts, Mohamed Abdel-Mohsen
Publikováno v:
Cell Reports, Vol 32, Iss 5, Pp 107991- (2020)
Summary: A comprehensive understanding of the phenotype of persistent HIV-infected cells, transcriptionally active and/or transcriptionally inactive, is imperative for developing a cure. The relevance of cell-surface glycosylation to HIV persistence
Externí odkaz:
https://doaj.org/article/7a931a3a4ffc4ff0895673a8784b2743
Autor:
Tongcui Ma, Xiaoyu Luo, Ashley F George, Gourab Mukherjee, Nandini Sen, Trimble L Spitzer, Linda C Giudice, Warner C Greene, Nadia R Roan
Publikováno v:
eLife, Vol 9 (2020)
The female reproductive tract (FRT) is the most common site of infection during HIV transmission to women, but viral remodeling complicates characterization of cells targeted for infection. Here, we report extensive phenotypic analyses of HIV-infecte
Externí odkaz:
https://doaj.org/article/e2465c199afb47b69b954f976129fd78
Autor:
Rahul K. Suryawanshi, Irene P. Chen, Tongcui Ma, Abdullah M. Syed, Noah Brazer, Prachi Saldhi, Camille R. Simoneau, Alison Ciling, Mir M. Khalid, Bharath Sreekumar, Pei-Yi Chen, G. Renuka Kumar, Mauricio Montano, Ronne Gascon, Chia-Lin Tsou, Miguel A. Garcia-Knight, Alicia Sotomayor-Gonzalez, Venice Servellita, Amelia Gliwa, Jenny Nguyen, Ines Silva, Bilal Milbes, Noah Kojima, Victoria Hess, Maria Shacreaw, Lauren Lopez, Matthew Brobeck, Fred Turner, Frank W. Soveg, Ashley F. George, Xiaohui Fang, Mazharul Maishan, Michael Matthay, Mary Kate Morris, Debra Wadford, Carl Hanson, Warner C. Greene, Raul Andino, Lee Spraggon, Nadia R. Roan, Charles Y. Chiu, Jennifer A. Doudna, Melanie Ott
Publikováno v:
Nature, vol 607, iss 7918
SARS-CoV-2 Delta and Omicron are globally relevant variants of concern. Although individuals infected with Delta are at risk of developing severe lung disease, infection with Omicron often causes milder symptoms, especially in vaccinated individuals1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a457aae7118cf5f209aea878cc86dd9
https://doi.org/10.1038/s41586-022-04865-0
https://doi.org/10.1038/s41586-022-04865-0
Autor:
Hannah S. Sperber, Kyle A. Raymond, Mohamed S. Bouzidi, Tongcui Ma, Silvana Valdebenito, Eliseo Eugenin, Nadia R. Roan, Roland Schwarzer, Satish K. Pillai
SUMMARYDeciphering the mechanisms underlying viral persistence is critical to achieving a cure for HIV infection. We uncovered molecular signatures of HIV latently-infected CD4+ T cells, identifying the adenosine-producing ectonucleotidase CD73 as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cea276fc74d1984e11ae047bb306060
https://doi.org/10.1101/2022.08.03.502655
https://doi.org/10.1101/2022.08.03.502655
Autor:
Jinbiao Liu, Qianhao Xiao, Runhong Zhou, Yong Wang, Qianyang Xian, Tongcui Ma, Ke Zhuang, Li Zhou, Deyin Guo, Xu Wang, WENZHE HO, Jieliang Li
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Altered T-cell homeostasis, such as expansion of CD8+ T cells to the secondary lymphatic compartments has been suggested as a mechanism of HIV/SIV-pathogenesis. However, the role of immune activation of CD8+ T cells in the CD4/CD8 turnover and viral
Externí odkaz:
https://doaj.org/article/33355fcf681344cb9c659328b5c3fd5b