Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Tongcheng Qian"'
Autor:
Tongcheng Qian, Tiffany M. Heaster, Angela R. Houghtaling, Kexin Sun, Kayvan Samimi, Melissa C. Skala
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Differentiation of hPSCs to cardiomyocytes suffers from high variability. Here the authors report a label-free live cell imaging platform based on autofluorescence imaging to enable the prediction of cardiomyocyte differentiation efficiency from hPSC
Externí odkaz:
https://doaj.org/article/c5d52f0785354812a3fc8a57e5918298
Autor:
Xiaoping Bao, Xiaojun Lian, Kaitlin K. Dunn, Mengxuan Shi, Tianxiao Han, Tongcheng Qian, Vijesh J. Bhute, Scott G. Canfield, Sean P. Palecek
Publikováno v:
Stem Cell Research, Vol 15, Iss 1, Pp 122-129 (2015)
Human pluripotent stem cell (hPSC)-derived endothelial cells and their progenitors are important for vascular research and therapeutic revascularization. Here, we report a completely defined endothelial progenitor differentiation platform that uses a
Externí odkaz:
https://doaj.org/article/e3daed5a73a44f4b8031b5458f4316cb
Publikováno v:
Current Opinion in Biomedical Engineering. 25:100435
Autor:
Benjamin D. Gastfriend, Kelsey Tweed, Daniel A. Gil, Emmanuel Contreras Guzman, Melissa C. Skala, Sean P. Palecek, Tongcheng Qian
Publikováno v:
Lab Chip
Endothelial cells (EC) in vivo are continuously exposed to a mechanical microenvironment from blood flow, and fluidic shear stress plays an important role in EC behavior. New approaches to generate physiologically and pathologically relevant pulsatil
Human pluripotent stem cell (hPSC)-derived cardiomyocytes provide a promising regenerative cell therapy for cardiovascular patients and an important model system to accelerate drug discovery. However, cost-effective and time-efficient platforms must
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16b4664083df4bd45aea1994583267a6
https://doi.org/10.21203/rs.3.pex-1569/v1
https://doi.org/10.21203/rs.3.pex-1569/v1
Human pluripotent stem cell (hPSC)-derived cardiomyocytes provide a promising regenerative cell therapy for cardiovascular patients and an important model system to accelerate drug discovery. However, cost-effective and time-efficient platforms must
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe29b2849a223eb485acf74e0ad08e7b
https://doi.org/10.21203/rs.3.pex-1571/v1
https://doi.org/10.21203/rs.3.pex-1571/v1
Autor:
Kayvan Samimi, Tongcheng Qian, Dan L. Pham, Emmanuel Contreras Guzman, Melissa C. Skala, Steven M. Trier
Publikováno v:
Label-free Biomedical Imaging and Sensing (LBIS) 2021.
A single photon-excited confocal whole-cell autofluorescence lifetime system is described that uses fast field-programmable gate array (FPGA)-based time tagging electronics to implement time-correlated single photon counting (TCSPC) with simultaneous
Autor:
Melissa C. Skala, Tongcheng Qian, Kayvan Samimi, Kexin Sun, Tiffany M. Heaster, Angela R. Houghtaling
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Human pluripotent stem cell (hPSC)-derived cardiomyocytes provide a promising regenerative cell therapy for cardiovascular patients and an important model system to accelerate drug discovery. However, cost-effective and time-efficient platforms must
Autor:
Melissa C. Skala, Kelsey Tweed, Sean P. Palecek, Daniel A. Gil, Tongcheng Qian, Emmanuel Contreras Guzman, Benjamin D. Gastfriend
Endothelial cells (EC) in vivo are continuously exposed to a mechanical microenvironment from blood flow, and fluidic shear stress plays an important role in EC behavior. New approaches to generate physiologically and pathologically relevant pulsatil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::814a8d647bac75234043fae678a5214d
https://doi.org/10.1101/2020.03.20.000752
https://doi.org/10.1101/2020.03.20.000752
Publikováno v:
Nature Protocols. 12:1890-1900
Here, we describe how to efficiently direct human pluripotent stem cells (hPSCs) differentiation into self-renewing epicardial cells in a completely defined, xeno-free system by temporal modulation of regulators of canonical Wnt signaling. Appropriat