Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Tongcheng Dai"'
Autor:
Tongcheng Dai, Hao Sun, Tyler Liban, Ildefonso Vicente-Suarez, Bin Zhang, Yongping Song, Zhongxing Jiang, Jifeng Yu, Jackie Sheng, Binhua Lv
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract We report the generation of a novel anti-LAG-3/TIGIT bispecific IgG4 antibody, ZGGS15, and evaluated its anti-tumor efficacy in mouse models as monotherapy or in combination with a PD-1 antibody. ZGGS15 exhibited strong affinities for human
Externí odkaz:
https://doaj.org/article/0562a51f66094c5ca19d04378fc77382
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 8, Iss 2, Pp 261-271 (2018)
The blood–brain barrier (BBB) and the blood–brain tumor barrier (BBTB) prevent drug and nano-drug delivery systems from entering the brain. However, ligand-mediated nano-drug delivery systems have significantly enhanced the therapeutic treatment
Externí odkaz:
https://doaj.org/article/029feaf76a0c4b55b54e3dc18eed30f0
Publikováno v:
Nanoscale Research Letters, Vol 12, Iss 1, Pp 1-10 (2017)
Abstract Many anti-cancer drugs have a common problem of poor solubility. Increasing the solubility of the drugs is very important for its clinical applications. In the present study, we revealed that the solubility of insoluble drugs was significant
Externí odkaz:
https://doaj.org/article/17a74f520cf640d08fa5e53a3222b6a0
Autor:
Ruifeng Liu, Alfonso Suarez, Tyler Liban, Bin Zhang, Tongcheng Dai, Margaret Karow, Jackie Sheng, Zelin Sheng, Binhua Lv, Bing Zhu
Publikováno v:
Cancer Research. 83:2323-2323
ZGGS18 is a bifunctional fusion protein targeting both human vascular endothelial growth factor (VEGF) and transforming growth factor-β (TGF-β), which consist of a monoclonal antibody against VEGF and an engineered extracellular domain of TGF-β re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb835773dea4997a123847df9ec7e16a
https://doi.org/10.1158/1538-7445.am2023-2323
https://doi.org/10.1158/1538-7445.am2023-2323
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 8, Iss 2, Pp 261-271 (2018)
Acta Pharmaceutica Sinica B, Vol 8, Iss 2, Pp 261-271 (2018)
The blood–brain barrier (BBB) and the blood–brain tumor barrier (BBTB) prevent drug and nano-drug delivery systems from entering the brain. However, ligand-mediated nano-drug delivery systems have significantly enhanced the therapeutic treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::052645828193a7850a136f5e81de3f4d
https://doi.org/10.1016/j.apsb.2018.01.004
https://doi.org/10.1016/j.apsb.2018.01.004
Autor:
Qin Liu, Yuanxing Zhang, Qiyao Wang, Chunshan Ni, Dahai Yang, Lingzhi Zhang, Tongcheng Dai, Wenting Xu
Publikováno v:
Journal of Bacteriology. 198:1534-1542
Edwardsiella tarda is an important pathogenic bacterium that can replicate in macrophages. However, how the intramacrophage infection process affects the virulence of this bacterium is essentially unknown. Here, we show that E. tarda replicates and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e04f362f2a3623c1fea4ee465cac4a3
https://doi.org/10.1128/jb.00978-15
https://doi.org/10.1128/jb.00978-15
The structure of ginsenoside (a) and silymarin (b). Figure S2. Topograph AFM images (a) and height profile (b) of RUB-based nanoparticles. Figure S3. Cell uptake of free C6 and RUB/C6 micelles in Caco-2 cells was imaged by confocal laser scanning mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58cf7f6b388e358182aa03b773d8b889
Publikováno v:
International Journal of Nanomedicine
Tongcheng Dai,1 Na Li,1 Lingzhi Zhang,1 Yuanxing Zhang,1,2 Qin Liu1,2 1State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 2Shanghai Collaborative Innovation Center for Biomanufacturing Technology, Shangha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b55a6804bf9b8b1694cc6f02e797849b
https://pubmed.ncbi.nlm.nih.gov/26811678
https://pubmed.ncbi.nlm.nih.gov/26811678
Publikováno v:
Biomaterials. 83
Active targeting-ligands have been increasingly used to functionalize nanoparticles for tumour-specific clinical applications. Here we utilize nucleotide adenosine 5'-monophosphate (AMP) as a novel ligand to functionalize polymer-based fluorescent na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::582effd136b3add1a331e3396c94ec46
https://pubmed.ncbi.nlm.nih.gov/26773664
https://pubmed.ncbi.nlm.nih.gov/26773664
Intracellular Cd2+ concentrations in macrophage J774A.1 cells incubated with quantum dots (50 nM) for 12 h were measured. Data are presented as means ± s.d. (n = 6). Figure S2. Colloidal stability of AMP-QDs in physiological media. AMP-QDs were incu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42449e50c60d77ef55ab3c9c6fe081bf